English   español  

Browsing by Author Fang, Wei-shuo S.

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 11 of 11
RightsPreviewIssue DateTitleAuthor(s)Type
openAccesstubulin_binding_Coderch.pdf.jpgMar-2013A structure-based design of new C2- and C13-substituted taxanes: Tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysisCoderch, Claire; Tang, Yong; Klett, Javier CSIC ORCID; Zhang, Shu-En; Ma, Yung-Tao; Shaorong, Wang; Matesanz, Ruth CSIC ; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Morreale, Antonio; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.; Gago, Federico CSIC ORCIDartículo
closedAccess15-Aug-2011Effects of C7 Substitutions in a High Affinity Microtubule-Binding Taxane on Antitumor Activity and Drug TransportXiao, Xi; Wu, Ju; Trigili, Chiara CSIC; Chen, Hui; Chu, Joseph W.K.; Zhao, Ying; Lu, Peihua; Sheng, Li; Li, Yan; Sharom, Frances J.; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.artículo
openAccessPera et al 2015.pdf.jpg1-Nov-2015High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cellsPera, Benet CSIC; Calvo, María Nieves; Ambati, Srikanth; Jordi, Michel; Kahn, Alissa; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.; Altmann, Karl-Heinz; Cerchietti, ,Leandro; Moore, Malcolm A. S.artículo
openAccess2017 Tang et al.pdf.jpg3-Jun-2017Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.Tang, Yong; Rodríguez-Salarichs, Javier; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.artículo
openAccessMatesanz_et_al_2011 Biophysical Journal.pdf.jpg21-Dec-2011Modulation of microtubule interprotofilament interactions by modified taxanesMatesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID; Bras, Wim; Nogales, Aurora CSIC ORCID; Fang, Wei-shuo S.; Díaz, José Fernando CSIC ORCID artículo
closedAccessMatesanz et al-2008_Chemistry and Biology.pdf.jpg23-Jun-2008Optimization of Taxane Binding to Microtubules: Binding Affinity Dissection and Incremental Construction of a High-Affinity Analog of PaclitaxelMatesanz, Ruth CSIC ; Barasoain, Isabel CSIC ; Yang, Chun-Gang; Wan, L.; Li, Xuan; Inés, Concepción de; Coderch, Claire; Gago, Federico CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Fang, Wei-shuo S.; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg14-May-2007Overcoming tumor drug resistance with high-affinity taxanes: A SAR study of C2-modified 7-acyl-10-deacetyl cephalomanninesYang, Chun-Gang; Barasoain, Isabel CSIC ; Li, Xuan; Matesanz, Ruth CSIC ; Liu, Ronghua; Sharom, Frances J.; Yin, Da-Li; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.artículo
closedAccessaccesoRestringido.pdf.jpg26-Mar-2010Probing the Pore Drug Binding Site of Microtubules with Fluorescent Taxanes: Evidence of Two Binding PosesBarasoain, Isabel CSIC ; García-Carril, Ana M.; Matesanz, Ruth CSIC ; Maccari, Giorgio; Trigili, Chiara CSIC; Mori, Mattia; Shi, Jing-Zhe; Fang, Wei-shuo S.; Andreu, José Manuel CSIC ORCID ; Botta, Maurizio; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg1-Feb-2009Synthesis and biological activities of high affinity taxane-based fluorescent probesLi, Xuan; Barasoain, Isabel CSIC ; Matesanz, Ruth CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.artículo
closedAccessrestringido.pdf.jpg2012Synthesis and Biological Evaluation of Colchicine B‑Ring Analogues Tethered with Halogenated Benzyl MoietiesCosentino, Laura; Redondo-Horcajo, Mariano CSIC ORCID ; Zhao, Ying; Santos, Ana Rita; Chowdury, Kaniz F.; Vinader, Victoria; Abdallah, Qasem M. A.; Abdel-Rahman, Hamdy; Fournier-Dit-Chabert, Jérémie; Shnyder, Steven D.; Loadman, Paul M.; Fang, Wei-shuo S.; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Burns, Philip A.; Pors, Klausartículo
closedAccessaccesoRestringido.pdf.jpg1-Jun-2007Synthesis, biological evaluations, and tubulin binding poses of C-2α sulfur linked taxol analoguesWang, Lei; Alcaraz, Ana A.; Matesanz, Ruth CSIC ; Yang, Chun-Gang; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Li, Ye-Zhi; Snyder, James P.; Fang, Wei-shuo S.artículo