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closedAccess7-Jul-2011A rigid lanthanide binding tag for NMR structural analysis of carbohydratesMallagaray, Alvaro CSIC ORCID; Canales, Ángeles CSIC ORCID; Domínguez, Gemma; Jiménez-Barbero, Jesús CSIC ORCID; Pérez-Castells, Javierartículo
openAccesstubulin_binding_Coderch.pdf.jpgMar-2013A structure-based design of new C2- and C13-substituted taxanes: Tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysisCoderch, Claire; Tang, Yong; Klett, Javier CSIC ORCID; Zhang, Shu-En; Ma, Yung-Tao; Shaorong, Wang; Matesanz, Ruth CSIC ; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Morreale, Antonio; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.; Gago, Federico CSIC ORCIDartículo
closedAccess22-Nov-2010Antimicrobial peptides and their superior fluorinated analogues: structure-activity relationships as revealed by NMR spectroscopy and MD calculationsDíaz, Dolores CSIC ORCID; Palomino-Schätzlein, M.; Corzana, Francisco; Andreu, C.; Carbajo, Rodrigo J.; Olmo, M. del; Canales, Ángeles CSIC ORCID; Pineda-Lucena, Antonio CSIC ORCID; Asensio, Gregorio; Jiménez-Barbero, Jesús CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg25-Jun-2017Applications of NMR to the development of novel protein ligands using dynamic combinatorial chemistrySastre Martinez J.; Martínez-González L.; Roca Carlos Pascual N.; Baldominos S.; Sánchez-Barrena, María José CSIC ORCID; Canales, Ángeles CSIC ORCID; Cañada, F. Javier ; Jiménez-Barbero, Jesús CSIC ORCID; Martínez, A.; Pérez-Fernández, Ruth CSIC ORCID póster de congreso
openAccessToro_et_al-2018-Angewandte_Chemie_International_Edition.pdf.jpg12-Nov-2018Avenues to characterize the interactions of extended N-Glycans with proteins by NMR spectroscopy: The influenza hemagglutinin caseFernández de Toro, Beatriz CSIC ; Peng, Wenjie; Thompson, Andrew J.; Domínguez, Gemma; Cañada, F. Javier ; Pérez-Castells, Javier; Paulson, James C.; Jiménez-Barbero, Jesús CSIC ORCID; Canales, Ángeles CSIC ORCIDartículo
closedAccess2006Backbone dynamics of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue, by 15N NMR relaxation methodsCanales, Ángeles CSIC ORCID; Fayos, Rosa CSIC; Angulo, Jesús CSIC ORCID ; Ojeda, Rafael; Martín-Pastor, Manuel; Nieto, Pedro M. CSIC ORCID ; Martín-Lomas, Manuel CSIC; Lozano, R.M. CSIC ORCID ; Giménez-Gallego, Guillermo CSIC; Jiménez-Barbero, Jesús CSIC ORCIDartículo
closedAccessrestringido.pdf.jpgNov-2009Cell wall polysaccharides isolated from the fungus Neotestudina rosatii, one of the etiologic agents of mycetoma in manLeal, J.A. CSIC; Giménez-Abián, M. I. CSIC; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Bernabé, Manuel CSIC; Prieto Orzanco, Alicia CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2018Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitorsChierrito, Talita P. C.; Pedersoli-Mantoani, S.; Roca, Carlos CSIC ORCID; Sebastián-Pérez, Víctor; Martínez-González, Loreto CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Canales, Ángeles CSIC ORCID; Cañada, F. Javier ; Campillo, Nuria E. CSIC ORCID ; Carvalho, Ivone; Martínez Gil, Ana CSIC ORCID artículo
openAccessNucl. Acids Res.-2011-Fernández-347-58.pdf.jpg2011Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complexFernández, Israel S. CSIC ORCID; Yamashita, Akio; Arias-Palomo, Ernesto CSIC ORCID ; Bamba, Yumi; Bartolomé, Rubén Álvaro CSIC ORCID ; Canales, Ángeles CSIC ORCID; Teixidó, Joaquín CSIC ORCID ; Ohno, Shigeo; Llorca, Óscar CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg5-Jul-2021Conformational and structural characterization of carbohydrates and their interactions studied by NMRCañada, F. Javier ; Canales, Ángeles CSIC ORCID; Valverde Vaquero, Pablo María; Fernández de Toro, Beatriz CSIC ; Martínez-Orts, M. CSIC; Oquist Phillips, Mayra Paola; Pereda, Amaia CSICartículo
closedAccess2-Apr-2005Conformational Flexibility of a Synthetic Glycosylaminoglycan Bound to a Fibroblast Growth Factor. FGF-1 Recognizes Both the 1C4 and 2SO Conformations of a Bioactive Heparin-like HexasaccharideCanales, Ángeles CSIC ORCID; Angulo, Jesús CSIC ORCID ; Ojeda, Rafael; Bruix, M. CSIC ORCID ; Fayos, Rosa CSIC; Lozano, R.M. CSIC ORCID ; Giménez-Gallego, Guillermo CSIC; Martín-Lomas, Manuel CSIC; Nieto, Pedro M. CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCIDartículo
closedAccess26-Sep-2011Conformational Selection of the AGA*IA(M) Heparin Pentasaccharide when Bound to the Fibroblast Growth Factor ReceptorNieto, Lidia CSIC; Canales, Ángeles CSIC ORCID; Giménez-Gallego, Guillermo CSIC; Nieto, Pedro M. CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCIDartículo
openAccessPREPRINTCrystal_structures_of_taxane-tubulin_complexes_Imp.pdf.jpg2021Crystal structures of taxane-tubulin complexes: Implications for the mechanism of microtubule stabilization by TaxolProta, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Ma, Yuntao; Estévez-Gallego, Juan CSIC ORCID ; Roca, Carlos CSIC ORCID; Josa-Prado, Fernando CSIC ORCID; Goossens, Kenneth; Giménez-Abián, Juan F. CSIC ; Li, Shuo; Canales, Ángeles CSIC ORCID; Bargsten, Katja; Andreu, José Manuel CSIC ORCID ; Altmann, Karl-Heinz; Olieric, Natacha; Kamimura, Shinji; Mühlethaler, Tobias; Oliva, María A. CSIC ORCID ; Steinmetz, Michel O.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID preprint
closedAccessrestringido.pdf.jpg12-Aug-2008Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440Jiménez, José Ignacio; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Ginalski, K.; Rychlewski, L.; García, José Luis CSIC ORCID ; Díaz, Eduardo CSIC ORCID artículo
openAccess2017 CEJ RAS.pdf.jpg2017Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic SignalingMarín-Ramos, Nagore I.; Piñar, Carmen; Vazquez-Villa, Henar; Martín-Fontecha, Mar; González, Ángel; Canales, Ángeles CSIC ORCID; Algar, S.; Mayo, Paloma P.; Jiménez-Barbero, Jesús CSIC ORCID; Gajate, Consuelo CSIC ORCID ; Mollinedo, Faustino CSIC ORCID ; Pardo, Leonardo; Ortega-Gutiérrez, S.; Viso, Alma CSIC ORCID ; López-Rodríguez, María L.artículo
openAccessCarbohy. Polym.Nácher-Vázquez_2015.pdf.jpg25-Jun-2015Dextrans produced by lactic acid bacteria exhibit antiviral and immunomodulatory activity against salmonid virusesNácher-Vázquez, Montserrat CSIC ORCID; Ballesteros, Natalia CSIC ORCID; Canales, Ángeles CSIC ORCID; Rodríguez Saint-Jean, Sylvia CSIC ; Pérez Prieto, Sara I. CSIC ; Prieto Orzanco, Alicia CSIC ORCID ; Aznar, Rosa CSIC ORCID; López García, Paloma CSIC ORCID artículo
openAccessCell Reports_G. Giménez Gallego_2015.pdf.jpg5-May-2015Discovery and characterization of an endogenous CXCR4 antagonist.Zirafi, O.; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Giménez-Gallego, Guillermo CSIC; Münch, Janartículo
openAccess2005 17 marzo Tesis Angeles Canales.pdf.jpg17-Mar-2005Estudios sobre el complejo monomérico, con actividad mitogénica, formado por el factor de crecimiento para fibroblastos ácido (FGF1) y un hexasacárido de diseño, análogo de heparina. Una visión estructural y dinámica utilizando RMN.Canales, Ángeles CSIC ORCIDtesis doctoral
closedAccessaccesoRestringido.pdf.jpg2021Genetic relationships among Canarian, African, and European goats using SNPsMacri, Martina; Martínez, Amparo; Luigi-Sierra, Maria Gracia CSIC ORCID; Capote, Juan; Canales, Ángeles CSIC ORCID; Amills, Marcel CSIC ORCID; Delgado, Juan Vicente; Fresno, M. R.póster de congreso
openAccessJ. Biol. Chem.-2010-Fernández-11714-29.pdf.jpg9-Apr-2010Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitorsFernández, Israel S. CSIC ORCID; López-Navajas, Pilar CSIC ; Canales, Ángeles CSIC ORCID; González-Corrochano, Rocío CSIC; Lozano, R.M. CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID; Romero, Antonio CSIC ORCID ; Giménez-Gallego, Guillermo CSICartículo