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RightsPreviewIssue DateTitleAuthor(s)Type
closedAccess16-Dec-19943'-->5' exonuclease active site of ø29 DNA polymerase. Evidence favoring a metal-ion-assisted reaction mechanismEsteban, José A. CSIC ORCID; Soenga, María S.; Salas, Margarita CSIC ORCID ; Blanco, Luis CSIC ORCIDartículo
openAccessBlancoL_ACancer-Associated.pdf.jpg4-Feb-2019A cancer-associated point mutation disables the steric gate of human PrimPolDíaz-Talavera, Alberto CSIC; Calvo, Patricia A.; González-Acosta, Daniel; Diaz, Marcos; Sastre-Moreno, Guillermo; Blanco-Franco, Luis; Guerra, Susana CSIC; Martínez-Jiménez, María I. CSIC ORCID ; Mendez, Juan; Blanco, Luis CSIC ORCIDartículo
closedAccess6-Oct-1989A conserved 3′→5′ exonuclease active site in prokaryotic and eukaryotic DNA polymerasesBernad, Antonio; Blanco, Luis CSIC ORCID; Lázaro, José M. CSIC; Martín, Gil; Salas, Margarita CSIC ORCID artículo
closedAccess1996A DNA binding motif coordinating synthesis and degradation in proofreading DNA polymerasesTruniger, Verónica CSIC ORCID ; Lázaro, José M. CSIC; Salas, Margarita CSIC ORCID ; Blanco, Luis CSIC ORCIDartículo
closedAccessApr-1991A general structure for DNA-dependent DNA polymerasesBlanco, Luis CSIC ORCID; Bernad, Antonio; Blasco, María A.; Salas, Margarita CSIC ORCID artículo
closedAccess19-Apr-2002A Highly Conserved Lysine Residue in φ29 DNA Polymerase is Important for Correct Binding of the Templating Nucleotide during Initiation of φ29 DNA ReplicationTruniger, Verónica CSIC ORCID ; Lázaro, José M. CSIC; Blanco, Luis CSIC ORCID; Salas, Margarita CSIC ORCID artículo
closedAccess29-Dec-1995A novel kinetic analysis to calculate nucleotide affinity of proofreading DNA polymerases. Application to ø29 DNA polymerase fidelity mutantsSaturno, Javier; Blanco, Luis CSIC ORCID; Salas, Margarita CSIC ORCID ; Esteban, José A. CSIC ORCIDartículo
openAccess14-Apr-2016A putative Leishmania DNA polymerase theta protects the parasite against oxidative damageFernández-Orgiler, Abel; Martínez-JimCrossed, María I.; Alonso, Ana CSIC ; Alcolea, Pedro J. CSIC ORCID ; Requena, José María CSIC ORCID CVN ; Thomas, María del Carmen; Blanco, Luis CSIC ORCID; Larraga, Vicente CSIC ORCID artículo
closedAccess2-Jul-1999A single tyrosine prevents insertion of ribonucleotides in the eukaryotic-type φ29 DNA polymeraseBonnin, Ana; Lázaro, José M. CSIC; Blanco, Luis CSIC ORCID; Salas, Margarita CSIC ORCID artículo
openAccessPNAS-2005-Rodríguez-6407-12[1].pdf.jpg3-May-2005A specific subdomain in 29 DNA polymerase confers both processivity and strand displacement capacityRodríguez García, Irene CSIC; Lázaro, José M. CSIC; Blanco, Luis CSIC ORCID; Kamtekar, S.; Berman, Andrea J.; Wang, J.; Steitz, T. A.; Salas, Margarita CSIC ORCID ; Vega, Miguel de CSIC ORCIDartículo
openAccessJAEsteban_NucleicAcidResearch_4932.pdf.jpg25-Sep-1992Activation of S1 nuclease at neutral pHEsteban, José A. CSIC ORCID; Salas, Margarita CSIC ORCID ; Blanco, Luis CSIC ORCIDartículo
openAccessjournal.pgen.1000389.pdf.jpgFeb-2009Altered Hematopoiesis in Mice Lacking DNA Polymerase μ Is Due to Inefficient Double-Strand Break RepairLucas, Daniel; Escudero, Beatriz; Ligos, José Manuel; Segovia, José Carlos; Estrada, Juan Camilo; Terrados, Gloria; Blanco, Luis CSIC ORCID; Samper, Enrique; Bernad, Antonioartículo
openAccessBlanco L Alternative solutions.pdf.jpg23-Feb-2015Alternative solutions and new scenarios for translesion DNA synthesis by human PrimPolMartínez-Jiménez, María I. CSIC ORCID ; García-Gómez, Sara CSIC; Bebenek, Katarzyna; Sastre-Moreno, Guillermo; Calvo, Patricia A.; Díaz-Talavera, Alberto CSIC; Kunkel, Thomas A.; Blanco, Luis CSIC ORCIDartículo
closedAccess1-Dec-2000An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminalDufour, Emmanuelle; Méndez, Juan; Lázaro, José M. CSIC; Vega, Miguel de CSIC ORCID; Blanco, Luis CSIC ORCID; Salas, Margarita CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg19-Sep-2005An intrinsic 5'-deoxyribose-5-phosphate lyase activity in DNA polymerase beta from Leishmania infantum supports a role in DNA repairAlonso, Ana CSIC ; Terrados, Gloria; Picher, Ángel J.; Giraldo, R. CSIC ORCID; Blanco, Luis CSIC ORCID; Larraga, Vicente CSIC ORCID artículo
closedAccess4-Jul-1997An invariant lysine residue is involved in catalysis at the 3′-5′ exonuclease active site of eukaryotic-type DNA polymerases1Vega, Miguel de CSIC ORCID; Ilyna, Tatjana; Lázaro, José M. CSIC; Salas, Margarita CSIC ORCID ; Blanco, Luis CSIC ORCIDartículo
closedAccess21-Jan-2000Analysis of Ø29 DNA polymerase by partial proteolysis: binding of terminal protein in the double-stranded DNA channelTruniger, Verónica CSIC ORCID ; Blanco, Luis CSIC ORCID; Salas, Margarita CSIC ORCID artículo
openAccessPNAS-1984-Blanco-5325-9.pdf.jpg1-Sep-1984Characterization and purification of a phage ø29 coded DNA polymerase required for the initiation of replicationBlanco, Luis CSIC ORCID; Salas, Margarita CSIC ORCID artículo
openAccessreferencia93.pdf.jpg1985Characterization of a 3'->5' exonuclease activity in the phage ø29-encoded DNA polymeraseBlanco, Luis CSIC ORCID; Salas, Margarita CSIC ORCID artículo
openAccessGTerrados_PlosOne_7290.pdf.jpg10-Jun-2009Characterization of a Natural Mutator Variant of Human DNA Polymerase l which Promotes Chromosomal Instability by Compromising NHEJTerrados, Gloria; Gapp, Jean-Pascal; Canitrot, Yvan; García, Miguel Ángel; Bebenek, Katarzyna; Kirchhoff, Tomas; Villanueva, Alberto; Boudsocq, François; Bergoglio, Valerie; Cazaux, Christophe; Kunkel, Thomas A.; Hoffmann, Jean-Sebastien; Blanco, Luis CSIC ORCIDartículo