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openAccessijms-20-01392.pdf.jpg20-mar-2019Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site LigandsBalaguer, Francisco de Asís CSIC ORCID; Mühlethaler, Tobias; Estévez-Gallego, Juan CSIC ORCID ; Calvo, Enrique; Giménez-Abián, Juan F. CSIC ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. CSIC ORCID ; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
openAccess12-jul-2021CTP promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional diffusion from parSBalaguer, Francisco de Asís CSIC ORCID; Aicart-Ramos, Clara; Fisher, Gemma LM; Bragança, Sara de; Martín-Cuevas, Eva María; Pastrana, César L.; Dillingham, Mark Simon; Moreno-Herrero, Fernandoartículo
openAccess2017 Tang et al.pdf.jpg3-jun-2017Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.Tang, Yong; Rodríguez-Salarichs, Javier CSIC; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuoartículo
openAccessPóster_González Rodríguez_2022.pdf.jpgjun-2022Molecular architecture and oligomerization of C. glabrata Cdc13 underpin its telomeric DNA binding and unfolding activityGonzalez-Rodriguez, Nayim; Coloma, Javier; Balaguer, Francisco de Asís CSIC ORCID; Gmurczyk, Karolina; Aicart-Ramos, Clara; Nuero, Óscar M. CSIC; Luque-Ortega, Juan Román CSIC ORCID ; Lue, Neal F.; Moreno-Herrero, Fernandopóster de congreso
openAccessMolecular architecture_Coloma_PV_Art2022.pdf.jpg2023Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activityColoma, Javier; Gonzalez-Rodriguez, Nayim; Balaguer, Francisco de Asís CSIC ORCID; Gmurczyk, Karolina; Aicart-Ramos, Clara; Nuero, Óscar M. CSIC; Luque-Ortega, Juan Román CSIC ORCID; Calugaru, Kimberly; Lue, Neal F.; Moreno-Herrero, Fernando; Llorca, Óscar CSIC ORCIDartículo
openAccessijms-18-01336.pdf.jpg22-jun-2017Quinolin-6-yloxyacetamides are microtubule destabilizing agents that bind to the colchicine site of tubulinSharma, Ashwani; Sáez-Calvo, Gonzalo CSIC; Olieric, Natacha; Balaguer, Francisco de Asís CSIC ORCID; Barasoain, Isabel CSIC ; Lamberth, Clemens; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.artículo
openAccesselife-Estévez-Gallego-2020.pdf.jpg10-mar-2020Structural model for differential cap maturation at growing microtubule endsEstévez-Gallego, Juan CSIC ORCID ; Josa-Prado, Fernando CSIC ORCID; Ku, Siou; Martínez Buey, Rubén CSIC ORCID; Balaguer, Francisco de Asís CSIC ORCID; Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Kamma-Lorger, C.S.; Yagi, Toshiki; Iwamoto, Hiroyuki; Duchesne, Laurence; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Chrétien, Denis; Kamimura, Shinji; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID artículo
openAccess14-nov-2019Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin IsotypesLa Sala, Giuseppina; Olieric, Natacha; Sharma, Ashwani; Viti, Federica; Balaguer, Francisco de Asís CSIC ORCID; Huang, Lan; Tonra, James R.; Lloyd, George Kenneth; Decherchi, Sergio; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.; Cavalli, Andreaartículo
closedAccessaccesoRestringido.pdf.jpg15-ene-2019Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agentsBrindisi, Margherita; Ulivieri, Cristina; Alfano, Gloria; Gemma, Sandra; Balaguer, Francisco de Asís CSIC ORCID; Khan, Tuhina; Grillo, Alessandro; Chemi, Giulia; Menchon, Grégory; Prota, Andrea E.; Olieric, Natacha; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Nebbioso, Angela; Conte, Mariarosaria; Lopresti, Ludovica; Magnano, Stefania; Amet, Rebecca; Kinsella, Paula; Zisterer, Daniela M.; Ibrahim, Ola; O'Sullivan, Jeff; Morbidelli, Lucia; Spaccapelo, Roberta; Baldari, Cosima T.; Butini, Stefania; Novellino, Ettore; Campiani, Giuseppe; Altucci, Lucia; Steinmetz, Michel O.; Brogi, Simoneartículo
openAccess4-ene-2019Synthesis of thicolchicine‐based conjugates: investigation towards bivalent tubulin/microtubules bindersBonandi, Elisa; Foschi, Francesca; Marucci, Cristina; Dapiaggi, Federico; Sironi, Maurizio; Pieraccini, Stefano; Christodoulou, M. S.; Balaguer, Francisco de Asís CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Zidar, Nace; Passarella, D.artículo
openAccessSaez-Calvo-et-al.2017.pdf.jpg22-jun-2017Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of TubulinSáez-Calvo, Gonzalo CSIC; Balaguer, Francisco de Asís CSIC ORCID; Barasoain, Isabel CSIC ; Rodríguez-Salarichs, Javier CSIC; Muñoz-Hernández, Hugo CSIC ORCID; Berbís, Manuel Álvaro CSIC; Peñalva, Miguel Ángel CSIC ORCID ; Matesanz, Ruth CSIC ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID artículo