Rights | Preview | Issue Date | Title | Author(s) | Type |
|  | 20-Mar-2019 | Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands | Balaguer, Francisco de Asís; Mühlethaler, Tobias; Estévez-Gallego, Juan ; Calvo, Enrique; Giménez-Abián, Juan F. ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. ; Prota, Andrea E.; Díaz, José Fernando | artículo |
closedAccess |  | 5-Oct-2009 | Epothilone Analogs with Benzimidazole and Quinoline Side Chains: Chemical Synthesis, Antiproliferative Activity, and Interactions with Tubulin | Dietrich, Silvia Anthoine; Lindauer, Renate; Stierling, Claire; Gertsch, Jürg; Matesanz, Ruth ; Notararigo, Sara ; Díaz, José Fernando ; Altmann, Karl-Heinz | artículo |
openAccess |  | 1-Nov-2015 | High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells | Pera, Benet ; Calvo, María Nieves; Ambati, Srikanth; Jordi, Michel; Kahn, Alissa; Díaz, José Fernando ; Fang, Wei-shuo S.; Altmann, Karl-Heinz; Cerchietti, ,Leandro; Moore, Malcolm A. S. | artículo |
closedAccess |  | 1-Feb-2013 | Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents | Prota, Andrea E.; Bargsten, Katja; Zurwerra, Didier; Field, Jessica J.; Díaz, José Fernando ; Altmann, Karl-Heinz; Steinmetz, Michel O. | artículo |
openAccess |  | 2020 | On the Importance of the Thiazole Nitrogen in Epothilones: Semisynthesis and Microtubule-Binding Affinity of Deaza-Epothilone C | Edenharter, Adriana; Ryckewaert, Lucie; Cintulová, Daniela; Estévez-Gallego, Juan ; Díaz, José Fernando ; Altmann, Karl-Heinz | artículo |
openAccess |  | 3-Aug-2016 | Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones) | Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Canales, Ángeles ; Altmann, Karl-Heinz | artículo |
openAccess |  | 3-Aug-2016 | Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones) | Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Canales, Ángeles ; Altmann, Karl-Heinz | artículo |
openAccess |  | 5-Mar-2019 | Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate | Gaugaz, Fabienne Z.; Chicca, Andrea; Redondo-Horcajo, Mariano ; Barasoain, Isabel ; Díaz, José Fernando ; Altmann, Karl-Heinz | artículo |
closedAccess |  | 3-Apr-2019 | Synthesis, profiling, and bioactive conformation of trans-Cyclopropyl Epothilones | Kuzniewski, Christian N.; Glauser, Simon; Gaugaz, Fabienne Z.; Schiess, Raphael; Rodríguez-Salarichs, Javier; Vetterli, Stefan; Horlacher, Oliver P.; Gertsch, Jürg; Redondo-Horcajo, Mariano ; Canales, Ángeles ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Altmann, Karl-Heinz | artículo |
openAccess |  | 3-May-2017 | Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration | Field, Jessica J.; Northcote, Peter; Paterson, Ian; Altmann, Karl-Heinz; Díaz, José Fernando ; Miller, John H. | artículo |
openAccess |  | 22-Jun-2012 | Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubules | Field, Jessica J.; Pera, Benet ; Calvo, Enrique; Canales, Ángeles ; Zurwerra, Didier; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús ; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel ; Altmann, Karl-Heinz; Díaz, José Fernando | artículo |