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Browsing by Author Altmann, Karl-Heinz

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Showing results 1 to 11 of 11
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ijms-20-01392.pdf.jpg20-Mar-2019Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site LigandsBalaguer, Francisco de Asís; Mühlethaler, Tobias; Estévez-Gallego, Juan ; Calvo, Enrique; Giménez-Abián, Juan F.  ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. ; Prota, Andrea E.; Díaz, José Fernando  artículo
closedAccessrestringido.pdf.jpg5-Oct-2009Epothilone Analogs with Benzimidazole and Quinoline Side Chains: Chemical Synthesis, Antiproliferative Activity, and Interactions with TubulinDietrich, Silvia Anthoine; Lindauer, Renate; Stierling, Claire; Gertsch, Jürg; Matesanz, Ruth ; Notararigo, Sara ; Díaz, José Fernando  ; Altmann, Karl-Heinzartículo
openAccessPera et al 2015.pdf.jpg1-Nov-2015High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cellsPera, Benet ; Calvo, María Nieves; Ambati, Srikanth; Jordi, Michel; Kahn, Alissa; Díaz, José Fernando  ; Fang, Wei-shuo S.; Altmann, Karl-Heinz; Cerchietti, ,Leandro; Moore, Malcolm A. S.artículo
closedAccessrestringido.pdf.jpg1-Feb-2013Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer AgentsProta, Andrea E.; Bargsten, Katja; Zurwerra, Didier; Field, Jessica J.; Díaz, José Fernando  ; Altmann, Karl-Heinz; Steinmetz, Michel O.artículo
openAccessImportance_Edenharter_Art2020.pdf.jpg2020On the Importance of the Thiazole Nitrogen in Epothilones: Semisynthesis and Microtubule-Binding Affinity of Deaza-Epothilone CEdenharter, Adriana; Ryckewaert, Lucie; Cintulová, Daniela; Estévez-Gallego, Juan ; Díaz, José Fernando  ; Altmann, Karl-Heinzartículo
openAccessmolecules-21-01010.pdf.jpg3-Aug-2016Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando  ; Canales, Ángeles ; Altmann, Karl-Heinzartículo
openAccessmolecules-2016.pdf.jpg3-Aug-2016Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones)Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando  ; Canales, Ángeles ; Altmann, Karl-Heinzartículo
openAccessijms-20-01113.pdf.jpg5-Mar-2019Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide ConjugateGaugaz, Fabienne Z.; Chicca, Andrea; Redondo-Horcajo, Mariano  ; Barasoain, Isabel ; Díaz, José Fernando  ; Altmann, Karl-Heinzartículo
closedAccessrestringido.pdf.jpg3-Apr-2019Synthesis, profiling, and bioactive conformation of trans-Cyclopropyl EpothilonesKuzniewski, Christian N.; Glauser, Simon; Gaugaz, Fabienne Z.; Schiess, Raphael; Rodríguez-Salarichs, Javier; Vetterli, Stefan; Horlacher, Oliver P.; Gertsch, Jürg; Redondo-Horcajo, Mariano  ; Canales, Ángeles ; Jiménez-Barbero, Jesús ; Díaz, José Fernando  ; Altmann, Karl-Heinzartículo
openAccessijms-18-00971-v2.pdf.jpg3-May-2017Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell MigrationField, Jessica J.; Northcote, Peter; Paterson, Ian; Altmann, Karl-Heinz; Díaz, José Fernando  ; Miller, John H.artículo
openAccessField et al 2012_Chemistry and Biology.pdf.jpg22-Jun-2012Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubulesField, Jessica J.; Pera, Benet ; Calvo, Enrique; Canales, Ángeles ; Zurwerra, Didier; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús ; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel ; Altmann, Karl-Heinz; Díaz, José Fernando  artículo