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Browsing by Author Agudo, Rubén

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Showing results 1 to 12 of 12
RightsPreviewIssue DateTitleAuthor(s)Type
openAccessAmulti_step_ProcessOfViralAdaptation.pdf.jpg2010A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escapeAgudo, Rubén ; Ferrer-Orta, Cristina  ; Arias, Armando ; Higuera, Ignacio de la ; Perales, Celia ; Pérez-Luque, Rosa  ; Verdaguer, Núria  ; Domingo, Esteban artículo
openAccessEDomingo_PlosOne_5554.pdf.jpg14-May-2009Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic TreatmentPerales, Celia ; Agudo, Rubén ; Domingo, Esteban artículo
openAccessBlancoL_EngineeringHUmanPrimpol.pdf.jpg12-Jul-2017Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymeraseAgudo, Rubén ; Calvo, Patricia A. ; Martínez-Jiménez, María I.  ; Blanco, Luis artículo
closedAccessaccesoRestringido.pdf.jpg10-Oct-2008Molecular Characterization of a Dual Inhibitory and Mutagenic Activity of 5-Fluorouridine Triphosphate on Viral RNA Synthesis. Implications for Lethal MutagenesisAgudo, Rubén ; Arias, Armando ; Pariente, Nonia; Perales, Celia ; Escarmís, Cristina; Jorge, Alberto; Marina, Anabel ; Domingo, Esteban artículo
closedAccessaccesoRestringido.pdf.jpg2013Molecular dissection of a viral quasispecies under mutagenic treatment: Positive correlation between fitness loss and mutational loadArias, Armando ; Ávila Lucas, Ana Isabel de ; Sanz-Ramos Rojo, Marta; Agudo, Rubén ; Escarmís, Cristina; Domingo, Esteban artículo
closedAccessaccesoRestringido.pdf.jpg11-Nov-2005Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA bindingArias, Armando ; Agudo, Rubén ; Ferrer-Orta, Cristina  ; Pérez-Luque, Rosa  ; Airaksinen, Antero; Brocchi, Emiliana; Domingo, Esteban ; Verdaguer, Núria  ; Escarmís, Cristinaartículo
closedAccessaccesoRestringido.pdf.jpg2010Mutation, quasispecies and lethal mutagenesisDomingo, Esteban ; Perales, Celia ; Agudo, Rubén ; Arias, Armando ; Escarmís, Cristina; Ferrer-Orta, Cristina  ; Verdaguer, Núria  capítulo de libro
openAccessEDomingo_PlosPath_1000658.pdf.jpg13-Nov-2009Potential Benefits of Sequential Inhibitor-Mutagen Treatments of RNA Virus InfectionsPerales, Celia ; Agudo, Rubén ; Tejero, Héctor; Manrubia Cuevas, Susanna; Domingo, Esteban artículo
closedAccessaccesoRestringido.pdf.jpgDec-2009Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymeraseFerrer-Orta, Cristina  ; Agudo, Rubén ; Domingo, Esteban ; Verdaguer, Núria  artículo
openAccessStructure of foot.pdf.jpg2010Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirinFerrer-Orta, Cristina  ; Sierra García, Macarena ; Agudo, Rubén ; Higuera, Ignacio de la ; Arias, Armando ; Pérez-Luque, Rosa  ; Escarmís, Cristina; Domingo, Esteban ; Verdaguer, Núria  artículo
closedAccessaccesoRestringido.pdf.jpg2-Feb-2006The structure of a protein primer-polymerase complex in the initiation of genome replicationFerrer-Orta, Cristina  ; Arias, Armando ; Agudo, Rubén ; Pérez-Luque, Rosa  ; Escarmís, Cristina; Domingo, Esteban ; Verdaguer, Núria  artículo
openAccess1471-2148-8-207.pdf.jpg17-Jul-2008Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selectionOjosnegros Martos, Samuel ; Agudo, Rubén ; Sierra García, Macarena ; Briones, Carlos ; Sierra, Saleta; González-López, Claudia; Domingo, Esteban ; Cristina, Juan artículo