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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| closedAccess |  | 2003 | Amifostine impairs p53-mediated apoptosis of human myeloid leukemia cells | Acosta, Juan C. CSIC ORCID; Richard, C.; Delgado, M. Dolores CSIC ORCID; Horita, M.; Rizzo, M. G.; Fernández-Luna, J. L.; León, Javier CSIC ORCID CVN | artículo |
| openAccess |  | 2022 | Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence | Fernández-Duran, Irene; Quintanilla, Andrea CSIC; Tarrats, Núria CSIC; Birch, Jodie; Hari, Priya; Millar, Fraser R.; Lagnado, Anthony B.; Smer-Barreto, Vanessa; Muir, Morwenna; Brunton, Valerie G.; Passos, João F.; Acosta, Juan C. CSIC ORCID | artículo |
| openAccess |  | 27-abr-2022 | Discovery of new senolytics using machine learning | Smer-Barreto, Vanessa; Quintanilla, Andrea CSIC; Elliot, Richard J. R.; Dawson, John C.; Sun, Jiugeng; Carragher, Neil O.; Acosta, Juan C. CSIC ORCID; Oyarzún, Diego A. | preprint |
| openAccess |  | 10-jun-2023 | Discovery of senolytics using machine learning | Smer-Barreto, Vanessa; Quintanilla, Andrea CSIC; Elliott, Richard J. R.; Dawson, John C.; Sun, Jiugeng; Campa, Víctor M. CSIC ORCID; Lorente-Macías, Álvaro; Unciti-Broceta, Asier; Carragher, Neil O.; Acosta, Juan C. CSIC ORCID; Oyarzún, Diego A. | artículo |
| openAccess |  | 2014 | High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycle | Caraballo, Juan M. CSIC; Acosta, Juan C. CSIC ORCID; Albajar, Marta CSIC; Gómez-Casares, M. Teresa; Batlle-López, Ana; Cuadrado, M. Ángeles CSIC; Bretones, Gabriel CSIC ORCID; Llorca, Javier; León, Javier CSIC ORCID CVN | artículo |
| openAccess |  | 15-abr-2022 | In vivo modeling of patient genetic heterogeneity identifies new ways to target cholangiocarcinoma | Younger, Nicholas T.; Wilson, Mollie L.; Martinez Lyons, Anabel; Jarman, Edward J.; Meynert, Alison M.; Grimes, Graeme R.; Gournopanos, Konstantinos; Waddell, Scott H.; Tennant, Peter A.; Wilson, David H.; Guest, Rachel V.; Wigmore, Stephen J.; Acosta, Juan C. CSIC ORCID; Kendall, Timothy J.; Taylor, Martin S.; Sproul, Duncan; Mill, Pleasantine; Boulter, Luke | artículo |
| closedAccess |  | 2009 | Inhibition of cell differentiation: A critical mechanism for MYC-mediated carcinogenesis? | León, Javier CSIC ORCID CVN; Ferrándiz, Nuria CSIC; Acosta, Juan C. CSIC ORCID; Delgado, M. Dolores CSIC ORCID | artículo de revisión |
| closedAccess |  | 2023 | MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells | Molina Hoyo, Ester CSIC ORCID; García-Gutiérrez, Lucía CSIC ORCID; Junco, Vanessa CSIC; Perez-Olivares, Mercedes; Yébenes, Virginia G. de; Blanco, Rosa CSIC; Quevedo, Laura CSIC ORCID; Acosta, Juan C. CSIC ORCID; Marín, Ana V.; Ulgiati, Daniela; Merino, Ramón CSIC ORCID; Delgado, M. Dolores CSIC ORCID; Varela, Ignacio CSIC ORCID; Regueiro, José R.; Moreno de Alborán, Ignacio; Ramiro, Almudena R.; León, Javier CSIC ORCID CVN | artículo |
| openAccess | | 2011 | MYC in chronic myeloid leukemia: Induction of aberrant DNA synthesis and association with poor response to imatinib | Albajar, Marta CSIC; Gómez-Casares, M. Teresa; Mauleon, Itaso; Vaqué, José P. CSIC ORCID; Acosta, Juan C. CSIC ORCID; Delgado, M. Dolores CSIC ORCID; León, Javier CSIC ORCID CVN | artículo |
| openAccess |  | 2008 | Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest | Acosta, Juan C. CSIC ORCID; Ferrándiz, Nuria CSIC; Bretones, Gabriel CSIC ORCID; Torrano, Verónica; Blanco, Rosa CSIC; Richard, C.; Delgado, M. Dolores CSIC ORCID; León, Javier CSIC ORCID CVN | artículo |
| openAccess |  | 2022 | MYC sensitises cells to apoptosis by driving energetic demand | Edwards-Hicks, Joy; Su, Huizhong; Mangolini, Maurizio; Yoneten, Kubra K.; Wills, Jimi; Rodriguez-Blanco, Giovanny; Young, Christine; Cho, Kevin; Barker, Heather; Muir, Morwenna; Guerrieri, Ania Naila; Li, Xue-Feng; White, Rachel; Manasterski, Piotr; Mandrou, Elena; Wills, Karen; Chen, Jingyu; Abraham, Emily; Sateri, Kianoosh; Qian, Bin-Zhi; Bankhead, Peter; Arends, Mark; Gammoh, Noor; Kriegsheim, Alexvon; Patti, Gary J.; Sim, Andrew H.; Acosta, Juan C. CSIC ORCID; Brunton, Valerie G.; Kranc, Kamil R.; Christophorou, Maria; Pearce, Erika L.; Ringshausen, Ingo; Finch, Andrew J. | artículo |
| openAccess |  | 2019 | Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27 | García-Gutiérrez, Lucía CSIC ORCID; Bretones, Gabriel CSIC ORCID; Molina Hoyo, Ester CSIC ORCID; Arechaga, Ignacio CSIC ORCID; Symonds, Catherine; Acosta, Juan C. CSIC ORCID; Blanco, Rosa CSIC; Fernández, Adrián; Alonso, Leticia; Sicinski, Piotr; Barbacid, Mariano CSIC; Santamaría, David; León, Javier CSIC ORCID CVN | artículo |
| closedAccess | | 29-abr-2022 | Regulation of the senescence-associated secretory phenotype by the nucleoporin TPR | Bartlett, Bethany; Kumar, Yatendra; Boumendil, Charlene; Acosta, Juan C. CSIC ORCID; Bickmore, Wendy | comunicación de congreso |
| openAccess |  | 1-dic-2022 | Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells | Altea-Manzano, Patricia; Vandekeere, Anke; Edwards-Hicks, Joy; Roldan, Mar; Abraham, Emily; Lleshi, Xhordi; Guerrieri, Ania Naila; Berardi, Domenica; Wills, Jimi; Marques Junior, Jair; Pantazi, Asimina; Acosta, Juan C. CSIC ORCID; Sanchez-Martin, Rosario M.; Fendt, Sarah-Maria; Martín-Hernández, Miguel; Finch, Andrew J. | artículo |
| openAccess |  | 7-dic-2022 | Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage | Ferreira-González , Sofía; Yung Man, Tak; Esser, Hannah; Aird, Rhona; Kilpatrick, Alastair M.; Rodrigo-Torres, Daniel; Younger, Nicholas T.; Campana, Lara; Gadd, Victoria L.; Dwyer, Benjamin; Aleksieva, Niya; Boulter, Luke; Macmillan, Mark T.; Wang, Yinmiao; Mylonas, Katie J.; Ferenbach, David A.; Kendall, Timothy J.; Lu, Wei-Yu; Acosta, Juan C. CSIC ORCID; Kurian, Dominic; O’Neill, Stephen; Oniscu, Gabriel C.; Banales, Jesús M.; Krimpenfort, Paul J.; Forbes, Stuart J. | artículo |
| closedAccess |  | ene-2011 | SKP2 oncogene is a direct MYC target gene and MYC downregulates p27KIP1 through SKP2 in human leukemia cells | Bretones, Gabriel CSIC ORCID; Acosta, Juan C. CSIC ORCID; Caraballo, Juan M. CSIC; Ferrándiz, Nuria CSIC; Gómez-Casares, M. Teresa; Albajar, Marta CSIC; Blanco, Rosa CSIC; Ruiz, Paula; León, Javier CSIC ORCID CVN | artículo |
| closedAccess |  | 2010 | SKP2 oncogene is a MYC target gene in human leukemia cells | León, Javier CSIC ORCID CVN; Bretones, Gabriel CSIC ORCID; Acosta, Juan C. CSIC ORCID; Caraballo, Juan M. CSIC; Ferrándiz, Nuria CSIC | comunicación de congreso |
| closedAccess |  | 6-sep-2022 | Supresión de tumores, senescencia celular, SASP y terapias innovadoras | Acosta, Juan C. CSIC ORCID | comunicación de congreso |
| closedAccess |  | 11-nov-2021 | The senescence-associated innate immune sensors in early-stage lung cancer treatment and diagnostics | Acosta, Juan C. CSIC ORCID | comunicación de congreso |
| closedAccess |  | 16-nov-2022 | Toll like receptor 2 orchestrates a potent tumor suppressor response in non small cell lung cancer | Acosta, Juan C. CSIC ORCID | póster de congreso |
