Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 5-ene-2023 | Chemical modulation of microtubule structure through the laulimalide/peloruside site | Estévez-Gallego, Juan CSIC ORCID ; Álvarez-Bernad, Beatriz CSIC; Benet, Pera; Wullschleger, Christoph; Raes, Olivier; Menche, Dirk; Martínez, Juan Carlos; Lucena-Agell, Daniel CSIC ORCID ; Prota, Andrea E.; Bonato, Francesca CSIC ORCID; Bargsten, Katja; Cornelus, Jelle; Giménez-Abián, Juan F. CSIC ; Northcote, Peter; Steinmetz, Michel O.; Kamimura, Shinji; Altmann, Karl-Heinz; Paterson, Ian; Gago, Federico CSIC ORCID; Van der Eycken, Johan; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID | artículo |
closedAccess | | 2-may-2005 | Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: Modification of the side chain | Paterson, Ian; Menche, Dirk; Håkansson, Anders E.; Longstaff, Adrian; Wong, David; Barasoain, Isabel CSIC ; Martínez Buey, Rubén CSIC ORCID; Díaz, José Fernando CSIC ORCID | artículo |
openAccess | | 19-ago-2011 | Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach | Canales, Ángeles CSIC ORCID; Rodríguez-Salarichs, Javier CSIC; Trigili, Chiara CSIC; Nieto, Lidia CSIC; Coderch, Claire; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID | artículo |
openAccess | | 16-dic-2021 | Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes | Rai, Ankit; Liu, Tianyang; Katrukha, Eugene A.; Estévez-Gallego, Juan CSIC ORCID ; Manka, Szymon W.; Paterson, Ian; Díaz, José Fernando CSIC ORCID ; Kapitein, Lukas C.; Moores, Carolyn A.; Akhmanova, Anna | artículo |
closedAccess | | 2005 | Microtubule interactions with chemically diverse stabilizing agents: Thermodynamics of binding to the paclitaxel site predicts cytotoxicity | Martínez Buey, Rubén CSIC ORCID; Barasoain, Isabel CSIC ; Jackson, Evelyn; Meyer, Arndt; Giannakakou, Paraskevi; Paterson, Ian; Mooberry, Susan; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID | artículo |
closedAccess | | 16-ago-2010 | Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity. | Pera, Benet CSIC; Razzak, Mina; Trigili, Chiara CSIC; Pineda, Oriol; Canales, Ángeles CSIC ORCID; Martínez Buey, Rubén CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Paterson, Ian; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID | artículo |
openAccess | | 16-feb-2017 | Structural basis of microtubule stabilization by discodermolide | Prota, Andrea E.; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Smith III, Amos B.; Yang, Chia-Ping H.; McDaid, Hayley M.; Paterson, Ian; Horwitz, Susan; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O. | artículo |
openAccess | | 13-dic-2016 | Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells | Trigili, Chiara CSIC; Barasoain, Isabel CSIC ; Sánchez-Murcia, Pedro A. CSIC ORCID; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Nogales, Aurora CSIC ORCID; Gardner, Nicola M.; Meyer, Arndt; Naylor, Guy J.; Gomez-Rubio, Elena CSIC ORCID; Gago, Federico CSIC ORCID; Steinmetz, Michel O.; Paterson, Ian; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID | artículo |
closedAccess | | ago-2008 | The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatin | Canales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Gardner, Nicola M.; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Díaz, José Fernando CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID | artículo |
openAccess | | 3-may-2017 | Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration | Field, Jessica J.; Northcote, Peter; Paterson, Ian; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID ; Miller, John H. | artículo |