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RightsPreviewIssue DateTitleAuthor(s)Type
closedAccess13-May-20096-Amino-6-deoxy-5,6-di-N-(N′-octyliminomethylidene)nojirimycin: Synthesis, Biological Evaluation, and Crystal Structure in Complex with Acid β-GlucosidaseBrumshtein, Boris; Aguilar Moncayo, Matilde ; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García-Fernández, José Manuel; Silman, Israel; Shaaltiel, Yoseph; Aviezer, David; Sussman, Joel L.; Futerman, Anthony H.Artículo
closedAccess9-Nov-2010A Fluorescent sp2-Iminosugar With Pharmacological Chaperone Activity for Gaucher Disease: Synthesis and Intracellular Distribution StudiesLuan, Zhuo; Higaki, Katsumi; Aguilar Moncayo, Matilde ; Li, Linjing; Ninomiya, Haruaki; Nanba, Eiji; Ohno, Kousaku; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García-Fernández, José Manuel; Suzuki, YoshiyukiArtículo
openAccessc5ra02627j.pdf.jpg2015Antileishmanial activity of sp2-iminosugar derivativesSánchez-Fernández, Elena M. ; Gómez-Pérez, Veronica; García-Hernández, Raquel; García-Fernández, José Manuel; Plata, Gabriela B.; Padrón, José M.; Ortiz-Mellet, Carmen; Catanys, Santiago; Gamarro, FranciscoArtículo
openAccessBicyclic (galacto)nojirimycin analogues as glycosidase inhibitors.pdf.jpg2011Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: Effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidaseAguilar Moncayo, Matilde ; García-Moreno, M. Isabel; Trapero, Ana; Egido-Gabás, Meritxell; Llebaria, Amadeu; García Fernández, José Manuel ; Ortiz-Mellet, CarmenArtículo
openAccessUS2010086648A1-1.pdf.jpg8-Apr-2010Caramels with high content in prebiotic oligosaccharides, procedure of preparation and useRubio Castillo, Enrique Miguel ; Gómez García, Marta ; Ortiz-Mellet, Carmen; García-Fernández, José Manuel; Zarzuelo Zurita, Antonio; Gálvez Peralta, Juan Julio; Duval, RaphaëlSolicitud de patente
closedAccess14-Oct-2009Chaperone Activity of Bicyclic Nojirimycin Analogues for Gaucher Mutations in Comparison with N-(n-nonyl)DeoxynojirimycinLuan, Zhuo; Higaki, Katsumi; Aguilar Moncayo, Matilde ; Ninomiya, Haruaki; Ohno, Kousaku; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García-Fernández, José Manuel; Suzuki, YoshiyukiArtículo
openAccessChemical_2008.pdf.jpg12-Aug-2008Chemical and Enzymatic Approaches to Carbohydrate-Derived Spiroketals: Di-D-Fructose Dianhydrides (DFAs)García Moreno, María Isabel; Benito, Juan M. ; Ortiz-Mellet, Carmen; García-Fernández, José ManuelArtículo
openAccess2346506_A1.pdf.jpg15-Oct-2010Ciclooligosacáridos anfifílicos policatiónicos y su uso como transportadores molecularesOrtiz-Mellet, Carmen; Méndez-Ardoy, Alejandro ; Gómez García, Marta ; Sevillano Trapero, Natalia; Girón González, María Dolores; Salto González, Rafael; Santoyo-González, F.; García-Fernández, José ManuelSolicitud de patente
closedAccess24-Feb-2010Comparative studies on lectin–carbohydrate interactions in low and high density homo- and heteroglycoclustersGómez García, Marta ; Benito, Juan M. ; Gutiérrez-Gallego, Ricardo; Maestre, Alfredo; Ortiz-Mellet, Carmen; García-Fernández, José Manuel; Jiménez Blanco, José L.Artículo
openAccessWO2010046517A1.pdf.jpg29-Apr-2010Compounds promoting the activity of mutant glycosidasesGarcía-Fernández, José Manuel; Ortiz-Mellet, Carmen; García Moncayo, M. Isabel; Suzuki, Yoshiyuki; Ohno, Kousaku; Aguilar Moreno, MatildeSolicitud de patente
openAccess2337435_A1.pdf.jpg23-Apr-2010Compuestos potenciadores de la actividad de glicosidasas mutantesGarcía-Fernández, José Manuel; Ortiz-Mellet, Carmen; García Moreno, María Isabel; Aguilar Moncayo, Matilde ; Suzuki, Yoshiyuki; Ohno, KousakuSolicitud de patente
openAccess2337435_B2.pdf.jpg25-Jan-2011Compuestos potenciadores de la actividad de glicosidasas mutantesGarcía Moreno, María Isabel; Ohno, Kousaku; García Fernández, José Manuel ; Suzuki, Yoshiyuki; Ortiz-Mellet, Carmen; Aguilar Moncayo, Matilde Patente
openAccessN-glycoside chaperones.pdf.jpg2015Conformationally-locked N -glycosides: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher diseaseCastilla, Javier; Rísquez-Cuadro, Rocio; Higaki, Katsumi; Nanba, Eiji; Ohno, Kousaku; Diaz, Yolanda; Ortiz-Mellet, Carmen; García-Fernández, José Manuel; Castillón, SergioArtículo
openAccessOB ART 10 2014 002204 R1.pdf.jpg2015Cyclodextrin- and calixarene-based polycationic amphiphiles as gene delivery systems: A structure-activity relationship studyGallego-Yerga, Laura; Lomazzi, Michela; Franceschi, Valentina; Sansone, Francesco; Ortiz-Mellet, Carmen; Donofrio, Gaetano; Canasti, Alessandro; García-Fernández, José ManuelArtículo
openAccess2011Cyclodextrin-based gene delivery systemsOrtiz-Mellet, Carmen; García Fernández, José Manuel ; Benito, Juan M. Artículo
openAccess2011Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analoguesBrumshtein, Boris; Aguilar Moncayo, Matilde ; Benito, Juan M. ; García Fernández, José Manuel ; Silman, Israel; Shaaltiel, Yoseph; Aviezer, David; Sussman, Joel L.; Futerman, Anthony H.; Ortiz-Mellet, CarmenArtículo
openAccessc4nj00700j.pdf.jpg2014Cyclodextrin-scaffolded amphiphilic aminoglucoside clusters: Self-assembling and gene delivery capabilitiesAguilar Moncayo, Matilde ; Guilloteau, M.; Bienvenu, Céline; Jiménez Blanco, José L.; Di Giorgio, Christophe; Vierling, Pierre; Benito, Juan M. ; Ortiz-Mellet, Carmen; García-Fernández, José ManuelArtículo
openAccessES2370852A1.pdf.jpg23-Dec-2011Derivados Sp2 imnoazúcar como inhibidores de las a-glicosidasasGarcía Fernández, José Manuel ; Sánchez, Elena; Ortiz-Mellet, Carmen; Rísquez-Cuadro, RocioSolicitud de patente
closedAccess28-Apr-2010Di-d-fructose Dianhydride-Enriched Caramels: Effect on Colon Microbiota, Inflammation, and Tissue Damage in Trinitrobenzenesulfonic Acid-Induced Colitic RatsArribas, Belén; Suárez Pereira, Elena; Ortiz-Mellet, Carmen; García-Fernández, José Manuel; Buttersack, Christoph; Rodríguez Cabezas, María Elena; Garrido Mesa, Natividad; Bailon, Elvira; Guerra Hernández, Eduardo; Zarzuelo Zurita, Antonio; Gálvez Peralta, Juan JulioArtículo
closedAccess29-Dec-2009Di-d-fructose Dianhydride-Enriched Products by Acid Ion-Exchange Resin-Promoted Caramelization of d-Fructose: Chemical AnalysesSuárez Pereira, Elena; Rubio Castillo, Enrique Miguel ; Pilard, Serge; Ortiz-Mellet, Carmen; García-Fernández, José ManuelArtículo