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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
closedAccess21-jun-2023Cathepsin D expressed in hepatocytes does not participate in the development of liver fibrosis after chronic CCl4 administrationRuiz-Blázquez, Paloma CSIC ORCID; Fernández-Fernández, María CSIC; Pistorio, Valeria CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID; Fernández-Checa, José C. CSIC ORCID; Moles, Anna CSIC ORCIDpóster de congreso
openAccess25-may-2022Cathepsin D is essential for the correct collagenolytic activity of macrophages during cholestatic-induced liver fibrosisRuiz-Blázquez, Paloma CSIC ORCID; Fernández-Fernández, María CSIC; Pistorio, Valeria CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Pavone, Luigi Michele; Fernández-Checa, José C. CSIC ORCID; Moles, Anna CSIC ORCIDcomunicación de congreso
openAccess8-nov-2021Cathepsin D is essential for the correct collagenolytic activity of macrophages during cholestatic-induced liver fibrosisFernández-Fernández, María CSIC; Pistorio, Valeria CSIC ORCID; Ruiz-Blázquez, Paloma CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCID; Moles, Anna CSIC ORCIDpóster de congreso
openAccessCholesterolenrichme_Solsona.pdf.jpgjun-2019Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexesSolsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Nuñez, Susana CSIC; Nuño-Lámbarri, Natalia; Enrich, Carlos; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg9-nov-2018Cholesterol loading in liver mitochondria alters mitochondrial morphology, respiration and respiratory supercomplexes assemblySolsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDcomunicación de congreso
closedAccessaccesoRestringido.pdf.jpg9-nov-2018Chronic alcohol feeding increases mitochondrial respiration in frg mice with humanized liverInsausti, Naroa CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Alarcón-Vila, Cristina CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDpóster de congreso
openAccessCheca - Extracellular Matrix Pharmacology Symposium (2021) - Collagenolytic activity in macrophages is dependent on lysosomal protease cathepsin D during liver fibrosis.pdf.jpg24-mar-2021Collagenolytic activity in macrophages is dependent on lysosomal protease cathepsin D during liver fibrosisPistorio, Valeria CSIC ORCID; Ruiz-Blázquez, Paloma CSIC ORCID; Fernández-Fernández, María CSIC; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCID; Moles, Anna CSIC ORCIDcomunicación de congreso
openAccess1-s2.0-S2213231722000039-main.pdf.jpgabr-2022Corrigendum to “Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation” [Redox Biol. 2021 45 102052]Torres, Sandra CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Matías, Nuria CSIC; Insausti, Naroa CSIC ORCID; Castro, Fernanda; Casasempere, Mireia; Fabriàs, Gemma CSIC ORCID ; Casas, Josefina CSIC ORCID ; Enrich, Carlos; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID corrigenda
openAccessCtsD deficient macrophages display altered proteolytic profile and dysregulated collagen recycling, resulting in increased liver fibrosis.pdf.jpg23-jun-2021CtsD deficient macrophages display altered proteolytic profile and dysregulated collagen recycling, resulting in increased liver fibrosisRuiz-Blázquez, Paloma CSIC ORCID; Pistorio, Valeria CSIC ORCID; Fernández-Fernández, María CSIC; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Pavone, Luigi Michele; Fernández-Checa, José C. CSIC ORCID; Moles, Anna CSIC ORCIDcomunicación de congreso
openAccessA.Moles - International Workshop on Liver and Gut Fibrosis (2021) - Defective proteolytic processing of collagen in macrophages enhances liver fibrosis.pdf.jpg7-oct-2021Defective proteolytic processing of collagen in macrophages enhances liver fibrosisRuiz-Blázquez, Paloma CSIC ORCID; Pistorio, Valeria CSIC ORCID; Fernández-Fernández, María CSIC; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Pavone, Luigi Michele; Fernández-Checa, José C. CSIC ORCID; Moles, Anna CSIC ORCIDcomunicación de congreso
openAccess13-ago-2021Dietary and Genetic Cholesterol Loading Rather Than Steatosis Promotes Liver Tumorigenesis and NASH-Driven HCCRibas, Vicent CSIC ORCID; Conde de la Rosa, Laura CSIC ORCID ; Robles, David CSIC; Nuñez, Susana CSIC; Segalés, Paula CSIC; Insausti, Naroa CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
openAccess1-s2.0-S2213231722003688-main.pdf.jpgfeb-2023Dietary and genetic disruption of hepatic methionine metabolism induce acid sphingomyelinase to promote steatohepatitisAlarcón-Vila, Cristina CSIC ORCID; Insausti, Naroa CSIC ORCID; Torres, Sandra CSIC ORCID; Segalés, Paula CSIC; Conde de la Rosa, Laura CSIC ORCID ; Nuñez, Susana CSIC; Fucho, Raquel CSIC ORCID; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
openAccess25-nov-2019Dietary cholesterol and overfeeding synergistically induce NASH and hepatocellular carcinoma in miceRobles, David CSIC; Vallejo, Carmen CSIC; Moles, Anna CSIC ORCID; Nuñez, Susana CSIC; Fucho, Raquel CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Insausti, Naroa CSIC ORCID; Ribas, Vicent CSIC ORCID; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID póster de congreso
openAccessEndoplasmic Reticulum_Torres.pdf.jpgago-2019Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver FailureTorres, Sandra CSIC ORCID; Baulies, Anna CSIC ORCID; Insausti, Naroa CSIC ORCID; Alarcón-Vila, Cristina CSIC ORCID; Fucho, Raquel CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Robles, David CSIC; Ribas, Vicent CSIC ORCID; Wakefield, Leslie; Grompe, Markus; Lucena, M. Isabel; Andrade, Raúl J.; Win, Sanda; Aung, Tin; Kaplowitz, Neil; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg10-abr-2019FRI-098-Targeting cholesterol with atorvastatin protects against valproic acid-induced sensitization to acetaminophen hepatotoxicityTorres, Sandra CSIC ORCID; Nuñez, Susana CSIC; Insausti, Naroa CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Ribas, Vicent CSIC ORCID; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDpóster de congreso
openAccess18-mar-2022GST-Perfringolysin O production for the localization and quantification of membrane cholesterol in human and mouse brain and liverGoicoechea, Leire CSIC ORCID; Arenas, Fabian CSIC ORCID; Castro, Fernanda; Nuñez, Susana CSIC; Torres, Sandra CSIC ORCID; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
openAccessHepatocyte cell-specific deletion of cathepsin D does not affect liver inflammation and fibrosis during cholestatic-induced liver fibrosis.pdf.jpg22-jun-2022Hepatocyte cell-specific deletion of cathepsin D does not affect liver inflammation and fibrosis during cholestatic-induced liver fibrosisFernández-Fernández, María CSIC; Ruiz-Blázquez, Paloma CSIC ORCID; Pistorio, Valeria CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCID; Moles, Anna CSIC ORCIDpóster de congreso
openAccess25-ene-2023Hepatocyte-associated cathepsin D does not contribute to the development of liver fibrosis.Ruiz-Blázquez, Paloma CSIC ORCID; Fernández-Fernández, María CSIC; Pistorio, Valeria CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID; Fernández-Checa, José C. CSIC ORCID; Moles, Anna CSIC ORCIDpóster de congreso
closedAccessaccesoRestringido.pdf.jpg13-nov-2015Key role of ASMase in the susceptibility of MAT1A deficient mice to choline deficient diet-induced steatohepatitisAlarcón-Vila, Cristina CSIC ORCID; Ribas, Vicent CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDpóster de congreso
openAccess9-nov-2020Macrophage cell-specific deletion of cathepsin D amplifies liver inflammation and fibrosisPistorio, Valeria CSIC ORCID; Ruiz-Blázquez, Paloma CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Fernández, María CSIC; Pavone, Luigi Michele; Fernández-Checa, José C. CSIC ORCID; Moles, Anna CSIC ORCIDpóster de congreso