Mostrando resultados 17 a 32 de 32
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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| closedAccess |  | 2014 | Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors | García, Ana M. CSIC ORCID; Brea, José Manuel; Morales-García, José A. CSIC ORCID; Pérez, Daniel I. CSIC ORCID; González, Alejandro CSIC ORCID; Alonso-Gil, Sandra CSIC; Conde, Santiago CSIC; Cadavid, María Isabel; Loza, María Isabel; Pérez Castillo, Ana CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID | artículo |
| closedAccess |  | 2001 | Multiple conformations of native and recombinant human 5-hydroxytryptamine2A receptors are labeled by agonists and discriminated by antagonists | López-Giménez, Juan F. CSIC ORCID; Villazón, María; Brea, José Manuel; Loza, María Isabel; Palacios, José M.; Mengod Los Arcos, Guadalupe CSIC ORCID; Vilaró, Maria Teresa CSIC ORCID | artículo |
| closedAccess |  | 2012 | Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model | Redondo, Miriam CSIC; Zarruk, Juan G.; Ceballos, Placido CSIC; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Pérez Castillo, Ana CSIC ORCID; Moro, María A.; Brea, José Manuel; Val, Cristina; Cadavid, María Isabel; Loza, María Isabel; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID | artículo |
| closedAccess |  | 8-dic-2001 | New serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonists: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones | Brea, José Manuel; Mengod Los Arcos, Guadalupe CSIC ORCID; Loza, María Isabel | artículo |
| openAccess |  | 2023 | Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models | Costa-Machado, Luis Filipe; García-Domínguez, Esther; McIntyre, Rebecca L.; López-Aceituno, José Luis; Ballesteros-González, Álvaro; Tapia-González, Andrea; Fabregat-Safont, David; Eisenberg, Tobias; Gómez, Jesús; Plaza, Adrian; Sierra-Ramírez, Aranzazu; Pérez, Manuel; Villanueva-Bermejo, David CSIC ORCID; Fornari, Tiziana CSIC ; Loza, María Isabel; Herradón, Gonzalo; Hofer, Sebastian J.; Magnes, Christoph; Madeo, Frank; Duerr, Janet S.; Pozo, Oscar J.; Galindo, Maximo-Ibo; Pino, Isabel del CSIC ORCID; Houtkooper, Riekelt H.; Megías, Diego; Viña, José; Gómez-Cabrera, Mari Carmen; Fernández-Marcos, Pablo José | artículo |
| closedAccess |  | 2-jun-2020 | Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease | Griñán-Ferré, Christian; Codony, Sandra; Pujol, Eugènia; Yang, Jun; Leiva, Rosana; Escolano, Carmen; Puigoriol-Illamola, Dolors; Companys-Alemany, Júlia; Corpas, Rubén CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Pérez, Belén CSIC ORCID; Loza, María Isabel; Brea, José Manuel; Morisseau, Christophe; Hammock, Bruce D.; Vázquez, Santiago; Pallàs, Mercè; Galdeano, Carles | artículo |
| closedAccess |  | 2017 | Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson’s disease | García, Ana M. CSIC ORCID; Salado, Irene G. CSIC; Pérez, Daniel I. CSIC ORCID; Brea, José Manuel; Morales-García, José A. CSIC ORCID; González-García, Alejandro; Cadavid, María Isabel; Loza, María Isabel; Luque, F. Javier; Pérez Castillo, Ana CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID | artículo |
| closedAccess |  | 2020 | Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M | Aragó, M.; Moreno-Felici, J.; Abás, S.; Rodríguez-Arévalo, S.; Hyroššová, P.; Figueras, A.; Viñals, F.; Pérez, B.; Loza, María Isabel; Brea, J.; Latorre, P.; Carrodeguas, José A. CSIC ORCID; García-Rovés, Pablo M.; Galdeano, Carles; Ginex, Tiziana CSIC ORCID ; Luque, F. Javier; Escolano, Carmen; Perales, J.C | artículo |
| openAccess |  | 3-abr-2022 | Soluble epoxide hydrolase inhibitors: design, synthesis, in vitro profiling and in vivo evaluation in murine models of pain | Vázquez, Santiago; Codony, Sandra; Entrena, José M.; Jora, Beatrice; González-Cano, Rafael; Loza, María Isabel; Brea, José Manuel; Morisseau, Christophe; Bartra Cabré, Clara CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Hammock, Bruce D.; Cobos, Enrique J. | póster de congreso |
| closedAccess |  | may-2022 | Soluble Epoxide Hydrolase Inhibitors: Design, Synthesis, in vitro Profiling and in vivo Evaluation in Murine Models of Pain | Vázquez, Santiago; Codony, Sandra; Entrena, José M.; Jora, Beatrice; González-Cano, Rafael; Loza, María Isabel; Brea, José Manuel; Morisseau, Christophe; Bartra Cabré, Clara CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Hammock, Bruce D.; Cobos, Enrique J. | artículo |
| openAccess |  | 7-abr-2011 | Substituted 5-IMINO-1,2,4-THIADIAZOLES that can be used to treat neurodegenerative diseases | Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Palomo, Valle CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Pérez Castillo, Ana CSIC ORCID; Loza, María Isabel; Cadavid, María Isabel; Brea, José Manuel | solicitud de patente |
| openAccess |  | 2022 | Supporting information Discovery and in Vivo Proof-of-Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer’s Disease | Codony, Sandra; Pont, Caterina; Griñán-Ferré, Christian; Di Pede-Mattatelli, Ania CSIC ORCID; Calvó-Tusell, Carla; Feixas, Ferran; Osuna, Sílvia; Jarné-Ferrer, Júlia; Naldi, Marina; Bartolini, Manuela; Loza, María Isabel; Brea, José Manuel; Pérez, Belén CSIC ORCID; Bartra Cabré, Clara CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Juárez-Jiménez, Jordi; Morisseau, Christophe; Hammock, Bruce D.; Pallàs, Mercè; Vázquez, Santiago; Muñoz-Torrero, Diego | dataset |
| closedAccess | | 2010 | Synthesis, biological activity and molecular docking analysis of new A2A adenosine receptor agonists | Rodríguez, Anna M.; Rosell, Gloria CSIC; Bujons, Jordi CSIC ORCID; Gutiérrez-de-Terán, Hugo; Rodríguez, David; Brea, José Manuel; Loza, María Isabel; Guerrero, Ángel CSIC ORCID; Bosch, María Pilar CSIC | artículo |
| openAccess |  | 2022 | Synthesis, in vitro profiling and in vivo evaluation of benzohomoadamantane-based ureas for visceral pain: a new indication for soluble epoxide hydrolase inhibitors | Codony, Sandra; Entrena, José M.; Calvó-Tusell, Carla; Osuna, Sílvia; Jora, Beatrice; González-Cano, Rafael; Corpas, Rubén CSIC ORCID; Morisseau, Christophe; Pérez, Belén CSIC ORCID; Barniol-Xicota, Marta; Griñán-Ferré, Christian; Pérez, Concepción CSIC ORCID; Rodríguez-Franco, María Isabel CSIC ORCID ; Martínez, Antón L.; Loza, María Isabel; Pallàs, Mercè; Verhelst, Steven H. L.; Sanfeliu, Coral CSIC ORCID; Feixas, Ferran; Hammock, Bruce D.; Brea, José Manuel; Cobos, Enrique J.; Vázquez, Santiago | artículo |
| closedAccess |  | 6-ene-2021 | Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML) | Sampaio-Dias, Ivo E.; Rodríguez-Borges, José E.; Yáñez-Pérez, Víctor; Arrasate, Sonia; Llorente, Javier; Brea, José M.; Bediaga, Harbil; Viña, Dolores; Loza, María Isabel; Caamaño, Olga; García-Mera, Xerardo; González-Díaz, Humberto CSIC ORCID | artículo |
| closedAccess |  | 2013 | Unraveling phosphodiesterase surfaces. Identification of phosphodiesterase 7 allosteric modulation cavities | Redondo, Miriam CSIC; Soteras, Ignacio CSIC ORCID; Brea, José Manuel; González-García, A.; Cadavid, María Isabel; Loza, María Isabel; Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Campillo, Nuria E. CSIC ORCID | artículo |
