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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| openAccess |  | 24-jul-2020 | Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6 | Pérez-Areales, F. Javier; Garrido, María CSIC; Aso, Ester; Bartolini, Manuela; De Simone, Angela; Espargaró, Alba; Ginex, Tiziana CSIC ORCID ; Sabate, Raimon; Pérez, Belén CSIC ORCID; Andrisano, Vincenza; Puigoriol-Illamola, Dolors; Pallàs, Mercè; Luque, F. Javier; Loza, María Isabel; Brea, José Manuel; Ferrer, Isidro; Ciruela, Francisco; Messeguer Peypoch, Ángel CSIC ORCID; Muñoz-Torrero, Diego | artículo |
| openAccess |  | 29-nov-2012 | Derivados heterocíclicos inhibidores de fosfodiesterasa 7 | Gil, Carmen CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Redondo, Miriam CSIC; Campillo, Nuria E. CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Loza, María Isabel; Cadavid, María Isabel; Brea, José Manuel; Pérez Castillo, Ana CSIC ORCID | solicitud de patente |
| openAccess |  | 24-mar-2022 | Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease | Codony, Sandra; Pont, Caterina; Griñán-Ferré, Christian; Di Pede-Mattatelli, Ania CSIC ORCID; Calvó-Tusell, Carla; Feixas, Ferran; Osuna, Sílvia; Jarné-Ferrer, Júlia; Naldi, Marina; Bartolini, Manuela; Loza, María Isabel; Brea, José Manuel; Pérez, Belén CSIC ORCID; Bartra Cabré, Clara CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Juárez-Jiménez, Jordi; Morisseau, Christophe; Hammock, Bruce D.; Pallàs, Mercè; Vázquez, Santiago; Muñoz-Torrero, Diego | artículo |
| openAccess |  | 2012 | Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds | Redondo, Miriam CSIC; Brea, José Manuel; Pérez, Daniel I. CSIC ORCID; Soteras, Ignacio CSIC ORCID; Val, Cristina; Pérez, Concepción CSIC ORCID; Morales-García, José A. CSIC ORCID; Alonso-Gil, Sandra CSIC; Paul-Fernández, Nuria CSIC; Martín-Álvarez, Rocío CSIC; Cadavid, María Isabel; Loza, María Isabel; Pérez Castillo, Ana CSIC ORCID; Mengod Los Arcos, Guadalupe CSIC ORCID; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID | artículo |
| closedAccess |  | 2020 | Essential role of the C148–C227 disulphide bridge in the human 5-HT2A homodimeric receptor | Cimadevila, M.; Gómez-García, L.; Martínez, A.L.; Iglesias, A.; López-Giménez, Juan F. CSIC ORCID; Castro, M.; Cadavid, María Isabel; Loza, María Isabel; Brea, J. | artículo |
| closedAccess |  | 11-mar-2009 | Evidence for distinct antagonist-revealed functional states of 5-hydroxytryptamine(2A) receptor homodimers | Vilaró, Maria Teresa CSIC ORCID; Mengod Los Arcos, Guadalupe CSIC ORCID; Loza, María Isabel | artículo |
| closedAccess |  | 2021 | His452Tyr polymorphism in the human 5-HT2A receptor affects clozapine-induced signaling networks revealed by quantitative phosphoproteomics | Martín-Guerrero, S.M.; Alonso, P.; Iglesias, A.; Cimadevila, M.; Brea, J.; Loza, María Isabel; Casado, Pedro; Martín-Oliva, David; Cutillas, Pedro; González-Maeso, Javier; López-Giménez, Juan F. CSIC ORCID | artículo |
| openAccess | | 7-sep-2023 | Hitting a new combination of biological targets to cope with Alzheimer's disease | Martínez-Conde, Noemí; Granje, Marc; Digito, Francesca; Mullins, Joseph J.; Griñán-Ferré, Christian; Jarne-Ferrer, Júlia; Naldi, Marina; Bartolini, Manuela; Loza, María Isabel; Brea, José Manuel; Pérez, Belén CSIC ORCID; Bartra Cabré, Clara CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Morisseau, Christophe; Hammock, Bruce D.; Pallàs, Mercè; Vázquez, Santiago; Muñoz-Torrero, Diego | comunicación de congreso |
| closedAccess |  | 7-mar-2023 | In vivo evaluation of soluble epoxide hydrolase inhibitors in murine models of allodynia, chemotherapy-induced neuropathic pain and visceral pain | Vázquez, Santiago; Codony, Sandra; Jora, Beatrice; Entrena, José M.; Santos-Caballero, M.; Turcu, Andreea L.; Calvó-Tusell, Carla; González-Cano, Rafael; Morisseau, Christophe; Martínez, Antón L.; Bartra Cabré, Clara CSIC ORCID; Corpas, Rubén CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Pérez, Belén CSIC ORCID; Hammock, Bruce D.; Pérez, Concepción CSIC ORCID ; Rodríguez-Franco, María Isabel CSIC ORCID ; Griñán-Ferré, Christian; Pallàs, Mercè; Osuna, Sílvia; Feixas, Ferran; Loza, María Isabel; Brea, José Manuel; Cobos, Enrique J. | póster de congreso |
| closedAccess |  | 2014 | Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors | García, Ana M. CSIC ORCID; Brea, José Manuel; Morales-García, José A. CSIC ORCID; Pérez, Daniel I. CSIC ORCID; González, Alejandro CSIC ORCID; Alonso-Gil, Sandra CSIC; Conde, Santiago CSIC; Cadavid, María Isabel; Loza, María Isabel; Pérez Castillo, Ana CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID | artículo |
| closedAccess |  | 2001 | Multiple conformations of native and recombinant human 5-hydroxytryptamine2A receptors are labeled by agonists and discriminated by antagonists | López-Giménez, Juan F. CSIC ORCID; Villazón, María; Brea, José Manuel; Loza, María Isabel; Palacios, José M.; Mengod Los Arcos, Guadalupe CSIC ORCID; Vilaró, Maria Teresa CSIC ORCID | artículo |
| closedAccess |  | 2012 | Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model | Redondo, Miriam CSIC; Zarruk, Juan G.; Ceballos, Placido CSIC; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Pérez Castillo, Ana CSIC ORCID; Moro, María A.; Brea, José Manuel; Val, Cristina; Cadavid, María Isabel; Loza, María Isabel; Campillo, Nuria E. CSIC ORCID ; Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID | artículo |
| closedAccess |  | 8-dic-2001 | New serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonists: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones | Brea, José Manuel; Mengod Los Arcos, Guadalupe CSIC ORCID; Loza, María Isabel | artículo |
| openAccess |  | 2023 | Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models | Costa-Machado, Luis Filipe; García-Domínguez, Esther; McIntyre, Rebecca L.; López-Aceituno, José Luis; Ballesteros-González, Álvaro; Tapia-González, Andrea; Fabregat-Safont, David; Eisenberg, Tobias; Gómez, Jesús; Plaza, Adrian; Sierra-Ramírez, Aranzazu; Pérez, Manuel; Villanueva-Bermejo, David CSIC ORCID; Fornari, Tiziana CSIC ; Loza, María Isabel; Herradón, Gonzalo; Hofer, Sebastian J.; Magnes, Christoph; Madeo, Frank; Duerr, Janet S.; Pozo, Oscar J.; Galindo, Maximo-Ibo; Pino, Isabel del CSIC ORCID; Houtkooper, Riekelt H.; Megías, Diego; Viña, José; Gómez-Cabrera, Mari Carmen; Fernández-Marcos, Pablo José | artículo |
| closedAccess |  | 2-jun-2020 | Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease | Griñán-Ferré, Christian; Codony, Sandra; Pujol, Eugènia; Yang, Jun; Leiva, Rosana; Escolano, Carmen; Puigoriol-Illamola, Dolors; Companys-Alemany, Júlia; Corpas, Rubén CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Pérez, Belén CSIC ORCID; Loza, María Isabel; Brea, José Manuel; Morisseau, Christophe; Hammock, Bruce D.; Vázquez, Santiago; Pallàs, Mercè; Galdeano, Carles | artículo |
| closedAccess |  | 2017 | Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson’s disease | García, Ana M. CSIC ORCID; Salado, Irene G. CSIC; Pérez, Daniel I. CSIC ORCID; Brea, José Manuel; Morales-García, José A. CSIC ORCID; González-García, Alejandro; Cadavid, María Isabel; Loza, María Isabel; Luque, F. Javier; Pérez Castillo, Ana CSIC ORCID; Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID | artículo |
| closedAccess |  | 2020 | Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M | Aragó, M.; Moreno-Felici, J.; Abás, S.; Rodríguez-Arévalo, S.; Hyroššová, P.; Figueras, A.; Viñals, F.; Pérez, B.; Loza, María Isabel; Brea, J.; Latorre, P.; Carrodeguas, José A. CSIC ORCID; García-Rovés, Pablo M.; Galdeano, Carles; Ginex, Tiziana CSIC ORCID ; Luque, F. Javier; Escolano, Carmen; Perales, J.C | artículo |
| openAccess |  | 3-abr-2022 | Soluble epoxide hydrolase inhibitors: design, synthesis, in vitro profiling and in vivo evaluation in murine models of pain | Vázquez, Santiago; Codony, Sandra; Entrena, José M.; Jora, Beatrice; González-Cano, Rafael; Loza, María Isabel; Brea, José Manuel; Morisseau, Christophe; Bartra Cabré, Clara CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Hammock, Bruce D.; Cobos, Enrique J. | póster de congreso |
| closedAccess |  | may-2022 | Soluble Epoxide Hydrolase Inhibitors: Design, Synthesis, in vitro Profiling and in vivo Evaluation in Murine Models of Pain | Vázquez, Santiago; Codony, Sandra; Entrena, José M.; Jora, Beatrice; González-Cano, Rafael; Loza, María Isabel; Brea, José Manuel; Morisseau, Christophe; Bartra Cabré, Clara CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Hammock, Bruce D.; Cobos, Enrique J. | artículo |
| openAccess |  | 7-abr-2011 | Substituted 5-IMINO-1,2,4-THIADIAZOLES that can be used to treat neurodegenerative diseases | Martínez Gil, Ana CSIC ORCID ; Gil, Carmen CSIC ORCID ; Palomo, Valle CSIC ORCID ; Pérez, Daniel I. CSIC ORCID; Pérez, Concepción CSIC ORCID; Pérez Castillo, Ana CSIC ORCID; Loza, María Isabel; Cadavid, María Isabel; Brea, José Manuel | solicitud de patente |
