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Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
closedAccess | | 2000 | H-, K- and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism | Delgado, M. Dolores CSIC ORCID; Vaqué, José P. CSIC ORCID; Arozarena, Imanol CSIC ORCID; López-Ilasaca, Marco A.; Martínez, Carlos; Crespo, Piero CSIC ORCID; León, Javier CSIC ORCID CVN | artículo |
openAccess | | 2009 | HCT116 cells deficient in p21Waf1 are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53 | Ferrándiz, Nuria CSIC; Martín-Pérez, Jorge CSIC ORCID ; Blanco, Rosa CSIC; Donertas, Derya; Delgado, M. Dolores CSIC ORCID; León, Javier CSIC ORCID CVN | artículo |
closedAccess | | 2014 | High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression and confer resistannce to apoptosis | León, Javier CSIC ORCID CVN | póster de congreso |
openAccess | | 2014 | High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycle | Caraballo, Juan M. CSIC; Acosta, Juan C. CSIC ORCID; Albajar, Marta CSIC; Gómez-Casares, M. Teresa; Batlle-López, Ana; Cuadrado, M. Ángeles CSIC; Bretones, Gabriel CSIC ORCID; Llorca, Javier; León, Javier CSIC ORCID CVN | artículo |
openAccess | | 17-jun-2012 | Inaugurado el Instituto de Biomedicina y Biotecnología de Cantabria | León, Javier CSIC ORCID CVN; Cruz, Fernando de la CSIC ORCID; Gabinete de Presidencia CSIC; Departamento de Comunicación CSIC | vídeo |
closedAccess | | 2014 | Induction of p27 degradation by Myc through CyclinA/CDK1 complexes | García-Gutiérrez, Lucía CSIC ORCID; Bretones, Gabriel CSIC ORCID; Arechaga, Ignacio CSIC ORCID; Santamaría, David; Barbacid, Mariano CSIC; León, Javier CSIC ORCID CVN | póster de congreso |
closedAccess | | 2009 | Inhibition of cell differentiation: A critical mechanism for MYC-mediated carcinogenesis? | León, Javier CSIC ORCID CVN; Ferrándiz, Nuria CSIC; Acosta, Juan C. CSIC ORCID; Delgado, M. Dolores CSIC ORCID | artículo de revisión |
closedAccess | | 2017 | Innovative methods for teaching molecular biology of the cell to medical students | Vaqué, José P. CSIC ORCID; Delgado, M. Dolores CSIC ORCID; Foltman, Magdalena CSIC ORCID; Navas Méndez, Jesús; Varela, Ignacio CSIC ORCID; León, Javier CSIC ORCID CVN; Sánchez-Díaz, Alberto CSIC ORCID | póster de congreso |
openAccess | | dic-2021 | JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia | Aranda-Tavío, Haidée; Recio, Carlota; Martín-Acosta, Pedro; Guerra-Rodríguez, Miguel; Brito-Casillas, Yeray; Blanco, Rosa CSIC; Junco, Vanessa CSIC; León, Javier CSIC ORCID CVN; Montero, Juan Carlos CSIC ORCID; Gandullo-Sánchez, Lucía CSIC ORCID; Grant McNaughton-Smith; Zapata, Juan M. CSIC ORCID ; Pandiella, Atanasio CSIC ORCID CVN ; Amesty, Ángel; Estévez-Braun, Ana; Fernández-Pérez, Leandro CSIC ORCID; Guerra, Borja CSIC ORCID | artículo |
openAccess | | 28-oct-2010 | Mecanismos moleculares responsables de la transformación en la leucemia mieloide crónica | León, Javier CSIC ORCID CVN; Albajar, Marta CSIC | comunicación de congreso |
closedAccess | | 16-nov-2022 | MNT knockdown effect on transcriptome and cell functions | Junco, Vanessa CSIC; Liaño-Pons, Judith CSIC ORCID; Lafita, M. Carmen CSIC ORCID; Delgado, M. Dolores CSIC ORCID; León, Javier CSIC ORCID CVN | póster de congreso |
openAccess | | 2016 | MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis | Lafita, M. Carmen CSIC ORCID; Blanco, Rosa CSIC; Mata-Garrido, Jorge; Liaño-Pons, Judith CSIC ORCID; Tapia, Olga; García-Gutiérrez, Lucía CSIC ORCID; García-Alegría, Eva CSIC; Berciano, María T.; Lafarga, Miguel; León, Javier CSIC ORCID CVN | artículo |
closedAccess | | may-2012 | MYC accelerates p21CIP-induced megakaryocytic differentiation involving early mitosis arrest in leukemia cells | Muñoz-Alonso, María J. CSIC; Ceballos, Laura; Bretones, Gabriel CSIC ORCID; Frade, Pilar; León, Javier CSIC ORCID CVN; Gandarillas, Alberto | artículo |
closedAccess | | 2015 | Myc and cell cycle control | Bretones, Gabriel CSIC ORCID; Delgado, M. Dolores CSIC ORCID; León, Javier CSIC ORCID CVN | artículo |
closedAccess | | 2013 | MYC antagonizes imatinib-induced differentiation in chronic myeloid leukemia cells through downregulation of p27KIP1 | Gómez-Casares, M. T.; García-Alegría, Eva CSIC; López-Jorge, C. E.; Ferrándiz, Nuria CSIC; Blanco, Rosa CSIC; Álvarez, S.; Vaqué, J. P.; Bretones, Gabriel CSIC ORCID; Caraballo, J. M.; Sánchez-Bailón, María Pilar CSIC ORCID; Delgado, M. Dolores CSIC ORCID; Martín-Pérez, Jorge CSIC ORCID ; Cigudosa, Juan C.; León, Javier CSIC ORCID CVN | artículo |
closedAccess | | 2023 | MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells | Molina Hoyo, Ester CSIC ORCID; García-Gutiérrez, Lucía CSIC ORCID; Junco, Vanessa CSIC; Perez-Olivares, Mercedes; Yébenes, Virginia G. de; Blanco, Rosa CSIC; Quevedo, Laura CSIC ORCID; Acosta, Juan C. CSIC ORCID; Marín, Ana V.; Ulgiati, Daniela; Merino, Ramón CSIC ORCID; Delgado, M. Dolores CSIC ORCID; Varela, Ignacio CSIC ORCID; Regueiro, José R.; Moreno de Alborán, Ignacio; Ramiro, Almudena R.; León, Javier CSIC ORCID CVN | artículo |
closedAccess | | 2012 | MYC impairs the diferentiation but not the growth arrest induced by Bcr-Abl through p27KIP1 down-regulation | García-Alegría, Eva CSIC; Gómez-Casares, M. Teresa; Delgado, M. Dolores CSIC ORCID; León, Javier CSIC ORCID CVN | comunicación de congreso |
openAccess | | 2011 | MYC in chronic myeloid leukemia: Induction of aberrant DNA synthesis and association with poor response to imatinib | Albajar, Marta CSIC; Gómez-Casares, M. Teresa; Mauleon, Itaso; Vaqué, José P. CSIC ORCID; Acosta, Juan C. CSIC ORCID; Delgado, M. Dolores CSIC ORCID; León, Javier CSIC ORCID CVN | artículo |
openAccess | | 2008 | Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest | Acosta, Juan C. CSIC ORCID; Ferrándiz, Nuria CSIC; Bretones, Gabriel CSIC ORCID; Torrano, Verónica; Blanco, Rosa CSIC; Richard, C.; Delgado, M. Dolores CSIC ORCID; León, Javier CSIC ORCID CVN | artículo |
closedAccess | | 2014 | Myc mediates the phosphorylation and degradation of p27 through activation of Cyclin A/CDK1 | García-Gutiérrez, Lucía CSIC ORCID; Bretones, Gabriel CSIC ORCID; Arechaga, Ignacio CSIC ORCID; Santamaría, David; Barbacid, Mariano CSIC; León, Javier CSIC ORCID CVN | póster de congreso |