Mostrando resultados 2 a 12 de 12
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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| | 2020 | Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy | Bautista-Aguilera, Óscar M. CSIC ORCID; Ismaili, Lhassane; Chioua, Mourad CSIC ORCID ; Andrys, R.; Schmidt, Monika; Bzonek, Petr; Martínez-Grau, Angeles; Beadle, C. D.; Vetman, T.; López-Muñoz, Francisco; Iriepa, Isabel; Refouvelet, Bernard; Musilek, Kamil; Marco-Contelles, José CSIC ORCID | artículo |
| openAccess |  | 2023 | Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation | Malek, R.; Simakov, Alexey; Davis, A.; Maj, Maciej; Bernard, P. J.; Wnorowski, Artur; Martin, Helene; Marco-Contelles, José CSIC ORCID; Chabchoub, Fakher; Dallemagne, Patrick; Rochais, C.; Józwiak, K.; Ismaili, Lhassane | artículo |
|  | 17-ene-2024 | Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties | Pachón-Angona, Irene; Bernard, Paul J.; Simakov, Alexey; Maj, Maciej; Jozwiak, Krzysztof; Novotna, Anna; Lemke, Carina; Gütschow, Michael; Martin, Helene; Oset-Gasque, María-Jesús; Contelles, José-Marco; Ismaili, Lhassane | artículo |
| openAccess |  | 14-mar-2020 | Design, synthesis and biological evaluation of new antioxidant and neuroprotective multitarget directed ligands able to block calcium channels | Pachòn Angona, Irene; Daniel, Solene; Martin, Hélène; Bonet, Alexandre; Wnorowski, Artur; Maj, Maciej; Jóźwiak, Krzysztof; Silva, Tiago Barros; Refouvelet, Bernard; Borges, Fernanda; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassane | artículo |
| openAccess |  | 4-jun-2023 | Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment | Dakhlaoui, I.; Bernard, P. J.; Pietrzak, Diana; Simakov, Alexey; Maj, Maciej; Refouvelet, Bernard; Béduneau, Arnaud; Cornu, Raphaël; Józwiak, K.; Chabchoub, Fakher; Iriepa, Isabel; Martin, Hélène; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassane | artículo |
| openAccess |  | 2019 | Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy | Dgachi, Youssef; Martin, Helene; Martin, Hélène; Malek, R; Jun, D.; Janockova, Jana; Sepsova, Vendula; Soukup, Ondrej; Iriepa, Isabel; Moraleda, Ignacio; Maalej, Enma; Carreiras, M. Carmo; Refouvelet, B.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassane | artículo |
| closedAccess |  | 2017 | Synthesis and biological assessment of racemic benzochromenopyrimidinetriones as promising agents for Alzheimer's disease therapy | Dgachi, Youssef; Martin, Hélène; Bonet, Alexandre; Chioua, Mourad CSIC ORCID ; Iriepa, Isabel; Moraleda, Ignacio; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassane | artículo |
| closedAccess | | 2024 | Synthesis and Biological Evaluation of New Benzochromenopyrimidines for the Therapy of Colon and Lung Cancer | Choura, Emna; El Ghali, Fares; Bernard, Paul J.; Marco-Contelles, José CSIC ORCID; Aifa, Sami; Ismaili, Lhassane; Chabchoub, Fakher | artículo |
| closedAccess |  | 2018 | Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, asmulti-target-directed ligands for Alzheimer's disease | Chioua, Mourad CSIC ORCID ; Buzzi, Eleonora; Moraleda, Ignacio; Iriepa, Isabel; Maj, Maciej; Wnorowski, Artur; Giovannini, Catia; Tamarin, Anna; Portali, Federica; Ismaili, Lhassane; López-Alvarado, Pilar; Bolognesi, Maria Laura; Jóźwiak, Krzysztof; Menéndez, J. Carlos; Marco-Contelles, José CSIC ORCID; Bartolini, Manuela | artículo |
| openAccess |  | ago-2023 | The Proof-of-Concept of MBA121, a Tacrine-Ferulic Acid Hybrid, for Alzheimer’s Disease Therapy | Rodríguez-Ruiz, Emelina R.; Herrero-Labrador, Raquel CSIC ORCID; Fernández Fernández, Ana Patricia CSIC; Serrano, Julia CSIC ORCID CVN; Martínez, José Antonio; González-Nieto, Daniel; Hana-Vaish, Mayuri; Benchekroun, Mohamed; Ismaili, Lhassane; Marco-Contelles, José CSIC ORCID; Martínez-Murillo, Ricardo CSIC ORCID | artículo |
| openAccess | | 2023 | The Proof-of-Concept of MBA121, a Tacrine¿Ferulic Acid Hybrid, for Alzheimer¿s Disease Therapy | Rodríguez-Ruiz, Emelina R.; Herrero-Labrador, Raquel CSIC ORCID; Fernández-Fernández, Ana P.; Serrano-Masa, Julia; Martínez-Montero, José A.; González-Nieto, Daniel; Hana-Vaish, Mayuri; Benchekroun, Mohamed; Ismaili, Lhassane; Marco-Contelles, José CSIC ORCID; Martínez-Murillo, Ricardo CSIC ORCID | artículo |
