Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 17-ago-2017 | Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses | Cortegano, Isabel CSIC; Rodriguez, Mercedes; Martin, Isabel; Prado, Maria Carmen; Ruiz, Carolina; Hortigüela, Rafael CSIC ORCID; Alía, Mario; Vilar, Marçal CSIC ORCID ; Mira, Helena CSIC ORCID ; Cano, Eva; Domínguez, Mercedes; de Andrés, Belén; Gaspar, María Luisa | artículo |
openAccess | | 15-oct-2009 | Apolipoprotein E genotyping method by real time PCR, a fast and cost-effective alternative to the TaqMan and FRET assays | Calero-Rueda, Olga CSIC; Hortigüela, Rafael CSIC ORCID; Bullido, María Jesús CSIC ORCID; Calero, Miguel | artículo |
openAccess | | 18-jun-2018 | BMP and WNT signalling cooperate through LEF1 in the neuronal specification of adult hippocampal neural stem and progenitor cells. | Armenteros, Tomás CSIC; Andreu, Zoraida; Hortigüela, Rafael CSIC ORCID; Lie, D. Chichung; Mira, Helena CSIC ORCID | artículo |
closedAccess | | 6-oct-2021 | Design, synthesis, and in vitro evaluation of tubulin-targeting dibenzothiazines with antiproliferative activity as a novel heterocycle building block | Guerra, Walter D.; Lucena-Agell, Daniel CSIC ORCID ; Hortigüela, Rafael CSIC ORCID; Rossi, Roberto A.; Díaz, José Fernando CSIC ORCID ; Padrón, José M.; Barolo, Silvia M. | artículo |
openAccess | | 31-ene-2022 | IDP-410: a novel therapeutic peptide that alters N-MYC stability and reduces angiogenesis and tumor progression in glioblastomas | Gargini, Ricardo CSIC ORCID; Segura-Collar, Berta; Garranzo Asensio, María; Hortigüela, Rafael CSIC ORCID; Iglesias-Hernández, Patricia; Lobato-Alonso, Daniel CSIC; Moreno-Raja, Miguel; Esteban-Martin, Santiago; Sepúlveda-Sánchez, Juan Manuel; Nevola, Laura; Sánchez-Gómez, Pilar CSIC | artículo |
embargoedAccess | | 5-nov-2023 | Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency | Ma, Yuntao; Josa-Prado, Fernando CSIC ORCID; Essif, Jacob Nathaniel; Liu, Shuqi; Li, Shuo; Lucena-Agell, Daniel CSIC ORCID ; Chan, Peter; Goossens, Kenneth; Hortigüela, Rafael CSIC ORCID; Matesanz, Ruth CSIC ; Wang, Yingjie; Gago, Federico CSIC ORCID; Wang, Hongbo; Risinger, April L.; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuo | artículo |
openAccess | | 6-nov-2018 | Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology | Díaz-Moreno, María; Armenteros, Tomás CSIC; Gradari, Simona CSIC; Hortigüela, Rafael CSIC ORCID; García-Corzo, Laura CSIC ORCID CVN; Fontán-Lozano, Ángela CSIC ORCID; Trejo, José L. CSIC ORCID; Mira, Helena CSIC ORCID | artículo |
openAccess | | 5-ago-2019 | Ocoxin Modulates Cancer Stem Cells and M2 Macrophage Polarization in Glioblastoma | Hernández-San Miguel, Esther; Gargini, Ricardo CSIC ORCID; Cejalvo, Teresa; Segura-Collar, Berta; Níñez-Hervada, Paula; Hortigüela, Rafael CSIC ORCID; Sepúlveda-Sánchez, Juan M.; Hernández-Laín, Aurelio; Pérez-Núñez, Angel; Sanz, Eduardo; Sánchez-Gómez, Pilar CSIC | artículo |
openAccess | | 31-ene-2024 | PM534, an optimized target-protein interaction strategy through the colchicine site of tubulin | Lucena-Agell, Daniel CSIC ORCID ; Guillén, María José; Matesanz, Ruth CSIC ; Álvarez-Bernad, Beatriz CSIC; Hortigüela, Rafael CSIC ORCID; Avilés, Pablo; Martínez-Díez, Marta; Santamaría, Gema; Contreras, Julia CSIC; Plaza-Menacho, Iván; Giménez-Abián, Juan F. CSIC ; Oliva, María A. CSIC ORCID ; Cuevas, Carmen; Díaz, José Fernando CSIC ORCID | artículo |
openAccess | | 21-oct-2023 | Probing a distinct druggable tubulin binding site with gatorbulins 1–7, their metabolic and physicochemical properties, and pharmacological consequences | Chen, Qi-Yin; Ratnayake, R.; Hortigüela, Rafael CSIC ORCID; Seabra, Gustavo M.; Cameron, Michael D.; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID ; Luesch, H. | artículo |
openAccess | | 28-nov-2022 | Targeting the tubulin C-terminal tail by charged small molecules | Li, Shuo; Mori, Mattia; Yang, Mingyan; Elfazazi, Soumia; Hortigüela, Rafael CSIC ORCID; Chan, Peter; Feng, Xinyue; Risinger, April L.; Yang, Zhiyou; Oliva, María A. CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuo | artículo |
openAccess | | 22-jul-2022 | The transcription factor LEF1 interacts with NFIX and switches isoforms during adult hippocampal neural stem cell quiescence | García-Corzo, Laura CSIC ORCID CVN; Calatayud-Baselga, Isabel CSIC ORCID; Casares-Crespo, Lucía CSIC; Mora-Martínez, Carlos CSIC; Escribano-Saiz, Juan Julián CSIC; Hortigüela, Rafael CSIC ORCID; Asenjo-Martinez, Andrea; Jordán-Pla, Antonio CSIC ORCID; Ercoli, Stefano CSIC; Flames, Nuria CSIC ORCID ; López-Alonso, Victoria; Vilar, Marçal CSIC ORCID | artículo |