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openAccessG5K_JMB2007.pdf.jpg13-abr-2007A Novel Two-domain Architecture Within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia coli Glutamate 5-kinaseMarco-Marín, Clara CSIC ORCID; Gil-Ortiz, Fernando CSIC ORCID; Pérez-Arellano, Isabel CSIC; Cervera, Javier; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
openAccessInsight.pdf.jpg18-abr-2012Insight on an arginine synthesis metabolon from the tetrameric structure of yeast acetylglutamate kinaseCima, Sergio de CSIC ORCID; Gil-Ortiz, Fernando CSIC ORCID; Crabeel, Marjolaine; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
openAccessgil.pdf.jpg2003N-Acetil-L-Glutamato quinasa de escherichia coli: Estructura tridimensional e implicaciones funcionalesGil-Ortiz, Fernando CSIC ORCIDtesis doctoral
openAccessGil-Acta-D-1999-v55-n7-p1350.pdf.jpg1999N-acetyi-L-glutamate kinase from Escherichia coli: Cloning of the gene, purification and crystallization of the recombinant enzyme and preliminary X-ray analysis of the free and ligand-bound formsGil-Ortiz, Fernando CSIC ORCID; Ramón-Maiques, Santiago CSIC ORCID ; Marina, Alberto CSIC ORCID ; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
openAccessPLoS ONE 2012-7- e31528.pdf.jpg20-feb-2012New Insight into the Transcarbamylase Family: The Structure of Putrescine Transcarbamylase, a Key Catalyst for Fermentative Utilization of AgmatinePolo, Luis Mariano CSIC ORCID; Gil-Ortiz, Fernando CSIC ORCID; Cantín, Ángel CSIC ORCID; Rubio, Vicente CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg24-feb-2006Structural bases of feed-back control of arginine biosynthesis, revealed by the structures of two hexameric N-acetylglutamate kinases, from Thermotoga maritima and Pseudomonas aeruginosaRamón-Maiques, Santiago CSIC ORCID ; Fernández-Murga, María Leonor CSIC; Gil-Ortiz, Fernando CSIC ORCID; Vagin, Alexei; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2002Structure of acetylglutamate kinase, a key enzyme for arginine biosynthesis and a prototype for the amino acid kinase enzyme family, during catalysisRamón-Maiques, Santiago CSIC ORCID ; Marina, Alberto CSIC ORCID ; Gil-Ortiz, Fernando CSIC ORCID; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2010Substrate binding and catalysis in carbamate kinase ascertained by crystallographic and site-directed mutagenesis studies: movements and significance of a unique globular subdomain of this key enzyme for fermentative ATP production in bacteriaRamón-Maiques, Santiago CSIC ORCID ; Marina, Alberto CSIC ORCID ; Guinot, Anna CSIC; Gil-Ortiz, Fernando CSIC ORCID; Uriarte, Matxalen; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg1-ago-2003The course of phosphorus in the reaction of N-Acetyl-L-glutamate kinase, determined from the structures of crystalline complexes, including a complex with an AlF4 - transition state mimicGil-Ortiz, Fernando CSIC ORCID; Ramón-Maiques, Santiago CSIC ORCID ; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
openAccess2007 PNAS 104-17644_vers aut.pdf.jpg6-nov-2007The crystal structure of the complex of PII and acetylglutamate kinase reveals how PII controls the storage of nitrogen as arginineLlácer, José Luis CSIC ORCID ; Contreras, Asunción; Forchhammer, Karl; Marco-Marín, Clara CSIC ORCID; Gil-Ortiz, Fernando CSIC ORCID; Maldonado, R.; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2010Two crystal structures of Escherichia coli N-acetyl-l-glutamate kinase demonstrate the cycling between open and closed conformationsGil-Ortiz, Fernando CSIC ORCID; Ramón-Maiques, Santiago CSIC ORCID ; Fernández-Murga, María Leonor CSIC; Rubio, Vicente CSIC ORCID artículo