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openAccess1-s2.0-S2213231721002111-main.pdf.jpgsep-2021Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulationTorres, Sandra CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Matías, Nuria CSIC; Insausti, Naroa CSIC ORCID; Castro, Fernanda; Casasempere, Mireia; Fabriàs, Gemma CSIC ORCID ; Casas, Josefina CSIC ORCID ; Enrich, Carlos; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
openAccessAnnexin A6 modulates TBC1D15 Rab7 StARD3 axis to control.pdf.jpg29-oct-2019Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cellsMeneses-Salas, Elsa; García-Melero, Ana; Kanerva, Kristiina; Blanco-Muñoz, Patricia; Morales-Paytuvi, Frederic; Bonjoch, Júlia; Casas, Josefina CSIC ORCID ; Egert, Antonia; Beevi, Syed S.; Jose, Jaimy; Llorente-Cortés, Vicenta CSIC ORCID; Rye, Kerry-Anne; Heeren, Joerg; Lu, Albert; Pol, Albert; Tebar, Francesc; Ikonen, Elina; Grewal, Thomas; Enrich, Carlos; Rentero, Carlesartículo
openAccesss41467-023-43896-7.pdf.jpg14-dic-2023Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulationMartinez-Campanario, M. C.; Cortés, Marlies; Moreno-Lanceta, Alazne; Han, Lu; Ninfali, Chiara; Domínguez, Verónica; Andrés-Manzano, María J.; Farràs, Marta; Esteve-Codina, Anna; Enrich, Carlos; Díaz-Crespo, Francisco J.; Pintado, Belén; Escolà-Gil, Joan Carles; García de Frutos, Pablo CSIC ORCID ; Andrés, Vicente CSIC ORCID; Melgar-Lesmes, Pedro; Postigo, Antonioartículo
closedAccessaccesoRestringido.pdf.jpgabr-2010Caveolin-1 regulates mitochondrial cholesterol and hepatocellular susceptibility to TNF/FASMarí, Montserrat CSIC ORCID ; Bosch, Marta; Fernández, Anna; Kassan, A.; Colell Riera, Anna CSIC ORCID; Enrich, Carlos; García-Ruiz, Carmen CSIC ORCID ; Pol, Albert; Fernández-Checa, José C. CSIC ORCIDcomunicación de congreso
openAccessCholesterolenrichme_Solsona.pdf.jpgjun-2019Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexesSolsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Nuñez, Susana CSIC; Nuño-Lámbarri, Natalia; Enrich, Carlos; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
openAccess1-s2.0-S2213231722000039-main.pdf.jpgabr-2022Corrigendum to “Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation” [Redox Biol. 2021 45 102052]Torres, Sandra CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Matías, Nuria CSIC; Insausti, Naroa CSIC ORCID; Castro, Fernanda; Casasempere, Mireia; Fabriàs, Gemma CSIC ORCID ; Casas, Josefina CSIC ORCID ; Enrich, Carlos; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID corrigenda
openAccessdefective.pdf.jpg15-ene-2003Defective TNF-α–mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout miceGarcía-Ruiz, Carmen CSIC ORCID ; Colell Riera, Anna CSIC ORCID; Marí, Montserrat CSIC ORCID ; Morales, Albert CSIC ORCID; Calvo, María; Enrich, Carlos; Fernández-Checa, José C. CSIC ORCIDartículo
openAccessGD3 synthase.pdf.jpg26-nov-2009GD3 synthase overexpression sensitizes hepatocarcinoma cells to hypoxia and reduces tumor growth by suppressing the cSrc/NF-κB survival pathwayLluis, Josep M. CSIC; Llacuna Duran, Laura CSIC; Montfort, Claudia von CSIC; Bárcena, Cristina CSIC ORCID; Enrich, Carlos; Morales, Albert CSIC ORCID; Fernández-Checa, José C. CSIC ORCIDartículo
openAccess5-oct-2023Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translationCortés, Marlies; Brischetto, Agnese; Martinez-Campanario, M. C; Ninfali, Chiara; Domínguez, Verónica; Fernández, Sara; Celis, Raquel; Esteve-Codina, Anna; Lozano, Juan J.; Sidorova, Julia; Garrabou, Gloria; Siegert, Anna-Maria; Enrich, Carlos; Pintado, Belén; Morales-Ruiz, Manuel; Castro, Pedro; Cañete, Juan D.; Postigo, Antonioartículo
samouillan-et-al-2023-inhibitory-effects-of-lrp1-based-immunotherapy-on-cardiac-extracellular-matrix-biophysical.pdf.jpg28-abr-2023Inhibitory Effects of LRP1-Based Immunotherapy on Cardiac Extracellular Matrix Biophysical Alterations Induced by HypercholesterolemiaSamouillan, Valerie; García, Eduardo; Benitez-Amaro, Aleyda CSIC ORCID; LaChica Lhoëst, Maria Teresa; Dandurand, Jany; Actis Dato, Virginia; Guerra Ramos, José María; Escolà-Gil, Joan Carles; Chiabrando, Gustavo Alberto; Enrich, Carlos; Llorente-Cortés, Vicenta CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg20-oct-2022La inmunoterapia basada en LRP1 como estrategia eficaz para inhibir las alteraciones metabólicas en el sistema cardiovascularActis Dato, Virginia; Benitez-Amaro, Aleyda CSIC ORCID; García, Eduardo; Claudi, Lene; LaChica Lhoëst, Maria Teresa; Iborra, Antoni; Escolà-Gil, Joan Carles; Guerra Ramos, José María; Samouillan, Valerie; Enrich, Carlos; Chiabrando, Gustavo Alberto; Llorente-Cortés, Vicenta CSIC ORCIDcomunicación de congreso
openAccessLysosomal_Torres.pdf.jpg30-nov-2017Lysosomal and mitochondrial liaisons in niemann-pick diseaseTorres, Sandra CSIC ORCID; Balboa, Elisa; Zanlungo, Silvana; Enrich, Carlos; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
openAccessMammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense.PDF.jpg16-oct-2020Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defenseBosch, Marta; Sánchez-Álvarez, Miguel; Fajardo, Alba; Kapetanovic, Ronan; Steiner, Bernhard; Dutra, Filipe; Moreira, Luciana; López, Juan Antonio; Campo, Rocío; Marí, Montserrat CSIC ORCID ; Morales-Paytuvi, Frederic; Tort, Olivia; Gubern, Albert; Templin, Rachel M.; Curson, James E. B.; Martel, Nick; Catalá, Cristina; Lozano, Francisco; Tebar, Francesc; Enrich, Carlos; Vázquez, Jesús CSIC ORCID CVN; Pozo Barriuso, Miguel Ángel del; Sweet, Matthew J.; Bozza, Patricia T.; Gross, Steven P.; Parton, Robert G.; Pol, Albertartículo
openAccessijms-23-07257-v2.pdf.jpg29-jun-2022Methuosis Contributes to Jaspine-B-Induced Cell DeathBielsa, Núria; Casasampere, Mireia CSIC ORCID; Abad, José Luis CSIC ORCID ; Enrich, Carlos; Delgado Cirilo, Antonio CSIC ORCID; Fabriàs, Gemma CSIC ORCID ; Lizcano, José M.; Casas, Josefina CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpgsep-2006Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitisMarí, Montserrat CSIC ORCID ; Caballero, Francisco CSIC; Colell Riera, Anna CSIC ORCID; Morales, Albert CSIC ORCID; Fernández, Anna; Enrich, Carlos; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
openAccessMitochondrial_Torres.pdf.jpgabr-2017Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C diseaseTorres, Sandra CSIC ORCID; Matías, Nuria CSIC; Baulies, Anna CSIC ORCID; Nuñez, Susana CSIC; Alarcón-Vila, Cristina CSIC ORCID; Martínez, Laura CSIC; Nuño-Lámbarri, Natalia; Fernández, Anna; Caballería, Juan; Levade, Thierry; Gonzalez-Franquesa, Alba; García-Rovés, Pablo M.; Balboa, Elisa; Zanlungo, Silvana; Fabriàs, Gemma CSIC ORCID ; Casas, Josefina CSIC ORCID ; Enrich, Carlos; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
openAccessAlonsoMA_MBoC_1252.pdf.jpg8-feb-2011MYADM regulates Rac1 targeting to ordered membranes required for cell spreading and migrationAranda, Juan Francisco CSIC ORCID; Reglero-Real, Natalia CSIC; Kremer, Leonor CSIC ORCID ; Marcos Ramiro, Beatriz CSIC; Ruiz-Sáenz, Ana CSIC ORCID; Calvo, Maria; Enrich, Carlos; Correas, Isabel CSIC ORCID; Millán, Jaime CSIC ORCID; Alonso, Miguel A. CSIC ORCIDartículo
openAccessTargeting cholesteryl ester accumulation in the heart improves cardiac insulin response.pdf.jpgago-2022Targeting cholesteryl ester accumulation in the heart improves cardiac insulin responseActis Dato, Virginia; Benitez-Amaro, Aleyda CSIC ORCID; García, Eduardo; Claudi, Lene; LaChica Lhoëst, Maria Teresa; Iborra, Antoni; Escolà-Gil, Joan Carles; Guerra Ramos, José María; Samouillan, Valerie; Enrich, Carlos; Chiabrando, Gustavo Alberto; Llorente-Cortés, Vicenta CSIC ORCIDartículo
openAccessAlonso M The MAL.pdf.jpg30-abr-2015The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongationReales, Elena CSIC; Bernabé-Rubio, Miguel CSIC ORCID; Casares-Arias, Javier CSIC ORCID; Rentero, Carles; Fernández-Barrera, Jaime CSIC ORCID; Rangel, Laura CSIC ORCID; Correas, Isabel CSIC ORCID; Enrich, Carlos; Andrés, Germán CSIC ORCID; Alonso, Miguel A. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpgjul-2021The role of the calmodulin-binding and calmodulin-like domains of the epidermal growth factor receptor in tyrosine kinase activationAbdelli, Faten; Jellali, Karim CSIC; Anguita, Estefanía CSIC; González-Muñoz, María CSIC; Villalobo, Eduardo CSIC ORCID; Madroñal, Iván; Alcalde Gómez, Juan; Ben Ali, Mamdouh; Elloumi-Mseddi, Jihene; Jemel, Ikram; Tebar, Francesc; Enrich, Carlos; Aifa, Sami; Villalobo, Antonio CSIC ORCIDartículo