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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
openAccess15-dic-2017Structural basis of membrane disruption and cellular toxicity by a-synuclein oligomersFusco, Giuliana; Chen, Serene W.; Williamson, Philip T. F.; Cascella, Roberta; Perni, Michele; Jarvis, James A.; Cecchi, Cristina; Vendruscolo, Michele; Chiti, Fabrizio; Cremades, Nunilo; Ying, Liming; Dobson, Christopher M.; De Simone, Alfonsoartículo
closedAccessaccesoRestringido.pdf.jpg2018The contribution of biophysical and structural studies of protein self-assembly to the design of therapeutic strategies for amyloid diseasesCremades, Nunilo; Dobson, C.M.artículo
openAccessThe extent of protein hydration.pdf.jpg15-oct-2020The extent of protein hydration dictates the preference for heterogeneous or homogeneous nucleation generating either parallel or antiparallel β-sheet α-synuclein aggregatesCamino, José D.; Gracia, Pablo; Chen, S.W.; Sot, Jesús CSIC ORCID; Arada, Igor de la CSIC ORCID; Sebastián, Víctor CSIC ORCID; Arrondo, José Luis R.; Goñi, Félix M. CSIC ORCID; Dobson, Christopher M.; Cremades, Nuniloartículo
openAccessα-synuclein.pdf.jpg22-mar-2021The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cellsCascella, Roberta; Chen, Serene W.; Bigi, A.; Camino, José D.; Xu, C.K.; Dobson, Christopher M.; Chiti, Fabrizio; Cremades, Nunilo; Cecchi, Cristinaartículo
openAccessα-synuclein.pdf.jpg22-mar-2021The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cellsCascella, Roberta; Chen, Serene W.; Bigi, A.; Camino, José D.; Xu, C.K.; Dobson, Christopher M.; Chiti, Fabrizio; Cremades, Nunilo; Cecchi, Cristinaartículo
openAccessThe release of toxic oligomers.pdf.jpg22-mar-2021The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cellsCascella, Roberta; Chen, Serene W.; Bigi, A.; Camino, José D.; Xu, C.K.; Dobson, Christopher M.; Chiti, Fabrizio; Cremades, Nunilo; Cecchi, Cristinaartículo
openAccessThe role of water.pdf.jpgfeb-2021The role of water in the primary nucleation of protein amyloid aggregationCamino, José D.; Gracia, Pablo; Cremades, Nuniloartículo
openAccessTrodusquemine displaces.pdf.jpg13-ago-2020Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanismLimbocker, Ryan; Mannini, Benedetta; Ruggeri, F.S.; Cascella, R.; Xu, C.K.; Perni, M.; Chia, S.; Chen, S.W.; Habchi, J.; Bigi, A.; Kreiser, R.P.; Wright, A.K.; Albright, J.A.; Kartanas, T.; Kumita, J.R.; Cremades, Nunilo; Zasloff, M.; Cecchi, C.; Knowles, T.P.J.; Chiti, Fabrizio; Vendruscolo, M.; Dobson, Christopher M.artículo
openAccessα-Helical peptidic scaffolds.pdf.jpg18-jun-2021α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinitySantos, Jaime; Gracia, Pablo; Navarro, Susanna; Peña-Díaz, Samuel; Pujols, Jordi; Cremades, Nunilo; Pallarés, Irantzu; Ventura, Salvadorartículo