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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| closedAccess |  | 12-oct-2020 | A method for the stereoselective construction of the hemiaminal center in zampanolides | Brütsch, Tobias M.; Berardozzi, Simone; Rothe, Marlene L.; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
| openAccess |  | 5-ene-2023 | Chemical modulation of microtubule structure through the laulimalide/peloruside site | Estévez-Gallego, Juan CSIC ORCID ; Álvarez-Bernad, Beatriz CSIC; Benet, Pera; Wullschleger, Christoph; Raes, Olivier; Menche, Dirk; Martínez, Juan Carlos; Lucena-Agell, Daniel CSIC ORCID ; Prota, Andrea E.; Bonato, Francesca CSIC ORCID; Bargsten, Katja; Cornelus, Jelle; Giménez-Abián, Juan F. CSIC ; Northcote, Peter; Steinmetz, Michel O.; Kamimura, Shinji; Altmann, Karl-Heinz; Paterson, Ian; Gago, Federico CSIC ORCID; Van der Eycken, Johan; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID | artículo |
| openAccess |  | 20-mar-2019 | Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands | Balaguer, Francisco de Asís CSIC ORCID; Mühlethaler, Tobias; Estévez-Gallego, Juan CSIC ORCID ; Calvo, Enrique; Giménez-Abián, Juan F. CSIC ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. CSIC ORCID ; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID | artículo |
| openAccess |  | 2021 | Crystal structures of taxane-tubulin complexes: Implications for the mechanism of microtubule stabilization by Taxol | Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Ma, Yuntao; Estévez-Gallego, Juan CSIC ORCID ; Roca, Carlos CSIC ORCID; Josa-Prado, Fernando CSIC ORCID; Goossens, Kenneth; Giménez-Abián, Juan F. CSIC ; Li, Shuo; Canales, Ángeles CSIC ORCID; Bargsten, Katja; Andreu, José Manuel CSIC ORCID ; Altmann, Karl-Heinz; Olieric, Natacha; Kamimura, Shinji; Mühlethaler, Tobias; Oliva, María A. CSIC ORCID ; Steinmetz, Michel O.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID | preprint |
| closedAccess |  | 5-oct-2009 | Epothilone Analogs with Benzimidazole and Quinoline Side Chains: Chemical Synthesis, Antiproliferative Activity, and Interactions with Tubulin | Dietrich, Silvia Anthoine; Lindauer, Renate; Stierling, Claire; Gertsch, Jürg; Matesanz, Ruth CSIC ; Notararigo, Sara CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
| openAccess |  | 1-nov-2015 | High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells | Pera, Benet CSIC; Calvo, María Nieves; Ambati, Srikanth; Jordi, Michel; Kahn, Alissa; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuo; Altmann, Karl-Heinz; Cerchietti, ,Leandro; Moore, Malcolm A. S. | artículo |
| openAccess |  | nov-2021 | Maytansinol derivatives: side reactions as a chance for new tubulin binders | Marzullo, Paola; Boiarska, Zlata; Pérez-Peña, Helena; Abel, Anne-Catherine; Álvarez-Bernad, Beatriz CSIC; Lucena-Agell, Daniel CSIC ORCID ; Vasile, Francesca; Sironi, Maurizio; Altmann, Karl-Heinz; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID ; Pieraccini, Stefano; Passarella, D. | artículo |
| closedAccess |  | 1-feb-2013 | Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents | Prota, Andrea E.; Bargsten, Katja; Zurwerra, Didier; Field, Jessica J.; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz; Steinmetz, Michel O. | artículo |
| openAccess |  | 2020 | On the Importance of the Thiazole Nitrogen in Epothilones: Semisynthesis and Microtubule-Binding Affinity of Deaza-Epothilone C | Edenharter, Adriana; Ryckewaert, Lucie; Cintulová, Daniela; Estévez-Gallego, Juan CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
| openAccess |  | 2011 | Shotgun and targeted MS analyses pinpoint the zampanolide-tubulin interacting site | Calvo, Enrique; Field, Jessica J.; Pera, Benet CSIC; Zuwerra, D.; López, Juan Antonio; Camafeita, Emilio; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID | póster de congreso |
| openAccess |  | 6-mar-2023 | Structural insight into the stabilization of microtubules by taxanes | Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Ma, Yuntao; Estévez-Gallego, Juan CSIC ORCID ; Li, Shuo; Bargsten, Katja; Josa-Prado, Fernando CSIC ORCID; Altmann, Karl-Heinz; Gaillard, Natacha; Kamimura, Shinji; Mühlethaler, Tobias; Gago, Federico CSIC ORCID; Oliva, María A. CSIC ORCID ; Steinmetz, Michel O.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID | artículo |
| closedAccess |  | 26-feb-2021 | Studies toward the synthesis of an oxazole-based analog of (−)-zampanolide | Bold, Christian Paul; Klaus, Cindy; Pfeiffer, Bernhard; Schürmann, Jasmine; Lombardi, Rafael; Lucena-Agell, Daniel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
| openAccess |  | 25-oct-2022 | Synthesis and biological evaluation of C(13)/C(13′)-Bis(desmethyl)disorazole Z** | Bold, Christian Paul; Lucena-Agell, Daniel CSIC ORCID ; Oliva, María A. CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
| openAccess |  | 2023 | Synthesis and structure-activity relationship studies of C(13)-desmethylene-(−)-zampanolide analogs | Brütsch, Tobias M.; Cotter, Etienne; Lucena-Agell, Daniel CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Davies, Carolina; Pfeiffer, Bernhard; Pagani, Sandro; Berardozzi, Simone; Díaz, José Fernando CSIC ORCID ; Miller, John H.; Altmann, Karl-Heinz | artículo |
| closedAccess |  | 1-abr-2021 | Synthesis of morpholine‐based analogues of (−)‐zampanolide and their biological activity | Bold, Christian Paul; Gut, Melanie; Schürmann, Jasmine; Lucena-Agell, Daniel CSIC ORCID ; Gertsch, Jürg; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
| openAccess |  | 3-ago-2016 | Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones) | Jantsch, Andrea; Nieto, Lidia CSIC; Gertsch, Jürg; Rodríguez-Salarichs, Javier CSIC; Matesanz, Ruth CSIC ; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Canales, Ángeles CSIC ORCID; Altmann, Karl-Heinz | artículo |
| openAccess |  | 5-mar-2019 | Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate | Gaugaz, Fabienne Z.; Chicca, Andrea; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
| closedAccess |  | 3-abr-2019 | Synthesis, profiling, and bioactive conformation of trans-Cyclopropyl Epothilones | Kuzniewski, Christian N.; Glauser, Simon; Gaugaz, Fabienne Z.; Schiess, Raphael; Rodríguez-Salarichs, Javier CSIC; Vetterli, Stefan; Horlacher, Oliver P.; Gertsch, Jürg; Redondo-Horcajo, Mariano CSIC ORCID ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
| closedAccess |  | mar-2020 | Taxanes convert regions of perturbed microtubule growth into rescue sites | Rai, Ankit; Liu, Tianyang; Glauser, Simon; Katrukha, Eugene A.; Estévez-Gallego, Juan CSIC ORCID ; Rodríguez-García, Ruddi; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.; Altmann, Karl-Heinz; Kapitein, Lukas C.; Moores, Carolyn A.; Akhmanova, Anna | artículo |
| closedAccess |  | oct-2014 | The impact of cyclopropane configuration on the biological activity of cyclopropyl-epothilones | Gaugaz, Fabienne Z.; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Cobos-Correa, Amanda; Kaufmann, Markus; Altmann, Karl-Heinz | artículo |
