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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| closedAccess |  | 2020 | Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization | Michalska, Patrycja; Buendía Abaitua, Izaskun; Duarte, Pablo; Fernández-Mendívil, Cristina; Negredo, Pilar; Cuadrado, Antonio CSIC ORCID; López, Manuela G.; León, Rafael CSIC ORCID | artículo |
| openAccess |  | may-2021 | Mine waters as a secondary source of rare earth elements worldwide: The case of the Iberian Pyrite Belt | León, Rafael CSIC ORCID ; Macías, F. CSIC ORCID; Cánovas, Carlos R.; Pérez-López, Rafael; Ayora, Carlos CSIC ORCID; Nieto, José Miguel; Olías, Manuel | artículo |
| closedAccess |  | 2021 | Monoamine Oxidase Inhibitors: from classic to new clinical approaches | Cuadrado, Antonio CSIC ORCID; León, Rafael CSIC ORCID | capítulo de libro |
| closedAccess |  | 2017 | Mortality Associated with Bacteremia Due to Colistin-Resistant Klebsiella pneumoniae with High-Level Meropenem Resistance: Importance of Combination Therapy without Colistin and Carbapenems | Machuca, Isabel; Gutiérrez-Gutiérrez, Belén CSIC ORCID; Gracia-Ahufinger, Irene; Rivera-Espinar, Francisco; Cano, Ángela; Guzmán-Puche, Julia; Pérez-Nadales, Elena; Natera, Clara; Rodríguez, Marina; León, Rafael CSIC ORCID ; Castón, Juan José; Rodríguez-López, Fernando; Rodríguez-Baño, Jesús CSIC ORCID; Torre-Cisneros, Julián | artículo |
| openAccess |  | 2018 | Multitarget compounds for the treatment of neurodegenerative diseases: Nrf2-EpRE pathway as key target | Michalska, Patrycja; Buendía Abaitua, Izaskun; Duarte, Pablo; Luengo, Enrique; Fernández-Mendívil, Cristina; Morales-García, José A. CSIC ORCID; Pérez Castillo, Ana CSIC ORCID; García López, Manuela; León, Rafael CSIC ORCID | comunicación de congreso |
| openAccess |  | 17-jul-2020 | Multitarget Virtual Screening for Drug Repurposing in COVID19 | Sorzano, Carlos Óscar S.; Crisman, Enrique CSIC; Carazo, José M.; León, Rafael CSIC ORCID | artículo |
| closedAccess | | 2011 | N-Acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer’s disease | González Muñoz, Gema C.; Arce, Mariana P. CSIC; López, Beatriz; López, Beatriz; Romero Jódar, Alejandro CSIC ORCID; del Barrio, Laura; Martín de Saavedra, María Dolores; Egea, Javier; León, Rafael CSIC ORCID ; Villarroya, Mercedes; López, Manuela G.; García, Antonio G.; Conde, Santiago CSIC; Rodríguez-Franco, María Isabel CSIC ORCID | artículo |
| openAccess |  | 8-jul-2019 | New neurogenic inducers with combined activities in key targets related to Alzheimer¿s disease | Herrera-Arozamena, Clara CSIC ORCID CVN; Estrada-Valencia, M.; Pérez, Concepción CSIC ORCID; Viña, D.; Michalska, Patrycja; León, Rafael CSIC ORCID ; López, M. G.; Morales-García, J. A.; Pérez-Castillo, Amalia; Rodríguez-Franco, María Isabel CSIC ORCID | comunicación de congreso |
| openAccess | | 4-nov-2019 | Non conventional targets for the treatment of Alzheimer's disease | López, M. G.; Luengo, E.; Trigo, P.; Fernández-Mendívil, Cristina; Franco, F.; Sastre, Eric del; Cuadrado, Antonio CSIC ORCID; Rodríguez-Franco, María Isabel CSIC ORCID ; León, Rafael CSIC ORCID | comunicación de congreso |
| closedAccess |  | 2013 | Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia | Lorrio, Silvia; Gómez-Rangel, Vanessa; Negredo, Pilar; Egea, Javier; León, Rafael CSIC ORCID ; Romero Jódar, Alejandro CSIC ORCID; Dal-Cim, Tharine.; Villarroya, Mercedes; Rodríguez-Franco, María Isabel CSIC ORCID ; Conde, Santiago CSIC; Arce, Mariana P. CSIC; Roda, José María; García, Antonio G.; López, Manuela G. | artículo |
| openAccess |  | 2022 | Novel Series of Dual NRF2 Inducers and Selective MAO-B Inhibitors for the Treatment of Parkinson's Disease | Duarte, Pablo; Michalska, Patrycja; Crisman, Enrique CSIC; Cuadrado, Antonio CSIC ORCID; León, Rafael CSIC ORCID | artículo de revisión |
| closedAccess |  | 2017 | Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices | Punzón, Eva; García-Alvarado, F.; Maroto, Marcos; Fernández-Mendívil, Cristina; Michalska, P.; García-Álvarez, Isabel; Arranz-Tagarro, J. A.; Buendía, Izaskun; López, M. G.; León, Rafael CSIC ORCID ; Gandía, Luis; Fernández-Mayoralas, Alfonso CSIC ORCID ; García, Antonio G. | artículo |
| openAccess |  | 3-jul-2019 | Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury | Rubio-Navarro, Alfonso; Vázquez-Carballo, Cristina; Guerrero-Hue, Melania; García-Caballero, Cristina; Herencia, Carmen; Gutiérrez, Eduardo; Yuste, Claudia; Sevillano, Ángel; Praga, Manuel; Egea, Javier; Cannata, Pablo; Cortegano, Isabel CSIC; Andrés, Belén de; Gaspar, María Luisa; Cadenas, Susana CSIC ORCID; Michalska, Patrycja; León, Rafael CSIC ORCID ; Ortiz, Alberto; Egido, Jesús; Moreno, Juan Antonio | artículo |
| closedAccess |  | 2013 | Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease | León, Rafael CSIC ORCID ; García, Antonio G.; Marco-Contelles, José CSIC ORCID | artículo |
| openAccess |  | mar-2022 | Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades | Herrera-Arozamena, Clara CSIC ORCID CVN; Estrada-Valencia, M.; López-Caballero, Patricia CSIC ORCID; Pérez, Concepción CSIC ORCID; Morales-García, José A. CSIC ORCID; Pérez-Castillo, Ana; Sastre, Eric del; Fernández-Mendívil, Cristina; Duarte, Pablo; Michalska, Patrycja; Lombardía, José; Senar, Sergio; León, Rafael CSIC ORCID ; López, Manuela G.; Rodríguez-Franco, María Isabel CSIC ORCID | artículo |
| closedAccess | | 2009 | Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer’s disease | Marco-Contelles, José CSIC ORCID; León, Rafael CSIC ORCID ; de los Ríos, Cristóbal; Samadi, Abdelouahid CSIC ORCID; Bartolini, Manuela; Andrisano, Vincenza; Huertas, Óscar; Barril, Xavier; Luque Garriga, Francisco Javier; Rodríguez-Franco, María Isabel CSIC ORCID ; López, Beatriz; López, Manuela G.; García, Antonio G.; do Carmo Carreiras, María; Villarroya, Mercedes | artículo |
| openAccess |  | 21-jul-2022 | Tetrahydro-spiroindoline-pyrrolopyrrole-triones inhibitors of the NRF2-Beta-TRCP interaction for use in the treatment of fatty liver disease | Cuadrado, Antonio CSIC ORCID; Fernández-Ginés, Raquel CSIC; Encinar, José Antonio; León, Rafael CSIC ORCID ; Franco-Gonzalez, Juan Felipe CSIC ORCID ; García López, Manuela; Rodríguez-Franco, María Isabel CSIC ORCID ; Rojo, Ana I. CSIC ORCID | solicitud de patente |
| openAccess |  | 20-jul-2022 | Tetrahydro-spiroindoline-pyrrolopyrrole-triones inhibitors of the NRF2-Beta-TRCP interaction for use in the treatment of NRF2-related diseases | Cuadrado, Antonio CSIC ORCID; Fernández-Ginés, Raquel CSIC; Encinar, José Antonio; León, Rafael CSIC ORCID ; Franco-Gonzalez, Juan Felipe CSIC ORCID ; García López, Manuela; Rodríguez-Franco, María Isabel CSIC ORCID ; Rojo, Ana I. CSIC ORCID | solicitud de patente |
| openAccess |  | 2019 | The angiotensin‐(1‐7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation | Romero, Alejandra; San Hipólito‐Luengo, Álvaro; Villalobos, Laura A.; Vallejo, Susana; Valencia, Inés; Michalska, Patrycja; Pajuelo-Lozano, Natalia CSIC; Sánchez-Pérez, Isabel CSIC ORCID; León, Rafael CSIC ORCID ; Bartha, José Luis; Sanz, Maria-Jesús; Erusalimsky, Jorge D.; Sánchez‐Ferrer, Carlos F.; Romacho, Tania; Peiró, Concepción | artículo |
| closedAccess |  | 2016 | The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators | Benchekroun, Mohamed; Romero Jódar, Alejandro CSIC ORCID; Egea, Javier; León, Rafael CSIC ORCID ; Michalska, P.; Buendía, I.; Jimeno, M. Luisa CSIC ORCID; Jun, Daniel; Janockova, Jana; Sepsova, V.; Soukup, Ondrej; Bautista-Aguilera, Óscar M. CSIC ORCID; Refouvelet, B.; Ouari, O.; Marco-Contelles, José CSIC ORCID; Ismaili, L. | artículo |
