Mostrando resultados 13 a 27 de 27
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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| closedAccess |  | 16-jul-2013 | New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism | Pera, Benet CSIC; Barasoain, Isabel CSIC ; Pantazopoulou, Areti CSIC ORCID; Canales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier CSIC; García-Fernández, Luis F. CSIC; Moneo, Victoria; Jiménez-Barbero, Jesús CSIC ORCID; Galmarini, Carlos M.; Cuevas, Carmen; Peñalva, Miguel Ángel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Andreu, José Manuel CSIC ORCID | artículo |
| openAccess |  | 2009 | Optimización de la interacción microtúbulo-taxol: Diseño de taxanos de alta afinidad | Matesanz, Ruth CSIC | tesis doctoral |
| closedAccess |  | 23-jun-2008 | Optimization of Taxane Binding to Microtubules: Binding Affinity Dissection and Incremental Construction of a High-Affinity Analog of Paclitaxel | Matesanz, Ruth CSIC ; Barasoain, Isabel CSIC ; Yang, Chun-Gang; Wan, L.; Li, Xuan; Inés, Concepción de CSIC; Coderch, Claire; Gago, Federico CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID | artículo |
| closedAccess |  | 14-may-2007 | Overcoming tumor drug resistance with high-affinity taxanes: A SAR study of C2-modified 7-acyl-10-deacetyl cephalomannines | Yang, Chun-Gang; Barasoain, Isabel CSIC ; Li, Xuan; Matesanz, Ruth CSIC ; Liu, Ronghua; Sharom, Frances J.; Yin, Da-Li; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuo | artículo |
| openAccess |  | 31-ene-2024 | PM534, an optimized target-protein interaction strategy through the colchicine site of tubulin | Lucena-Agell, Daniel CSIC ORCID ; Guillén, María José; Matesanz, Ruth CSIC ; Álvarez-Bernad, Beatriz CSIC; Hortigüela, Rafael CSIC ORCID; Avilés, Pablo; Martínez-Díez, Marta; Santamaría, Gema; Contreras, Julia CSIC; Plaza-Menacho, Iván; Giménez-Abián, Juan F. CSIC ; Oliva, María A. CSIC ORCID ; Cuevas, Carmen; Díaz, José Fernando CSIC ORCID | artículo |
| closedAccess |  | 26-mar-2010 | Probing the Pore Drug Binding Site of Microtubules with Fluorescent Taxanes: Evidence of Two Binding Poses | Barasoain, Isabel CSIC ; García-Carril, Ana M.; Matesanz, Ruth CSIC ; Maccari, Giorgio; Trigili, Chiara CSIC; Mori, Mattia; Shi, Jing-Zhe; Fang, Wei-Shuo; Andreu, José Manuel CSIC ORCID ; Botta, Maurizio; Díaz, José Fernando CSIC ORCID | artículo |
| closedAccess |  | 1-feb-2009 | Synthesis and biological activities of high affinity taxane-based fluorescent probes | Li, Xuan; Barasoain, Isabel CSIC ; Matesanz, Ruth CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuo | artículo |
| closedAccess |  | 1-jun-2007 | Synthesis, biological evaluations, and tubulin binding poses of C-2α sulfur linked taxol analogues | Wang, Lei; Alcaraz, Ana A.; Matesanz, Ruth CSIC ; Yang, Chun-Gang; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Li, Ye-Zhi; Snyder, James P.; Fang, Wei-Shuo | artículo |
| openAccess |  | 3-ago-2016 | Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones) | Jantsch, Andrea; Nieto, Lidia CSIC; Gertsch, Jürg; Rodríguez-Salarichs, Javier CSIC; Matesanz, Ruth CSIC ; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Canales, Ángeles CSIC ORCID; Altmann, Karl-Heinz | artículo |
| openAccess |  | 19-jun-2014 | Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances | Matesanz, Ruth CSIC ; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier CSIC; Pera, Benet CSIC; Jiménez-Barbero, Jesús CSIC ORCID; Canales, Ángeles CSIC ORCID; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID | artículo |
| closedAccess |  | ago-2008 | The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatin | Canales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Gardner, Nicola M.; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Díaz, José Fernando CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID | artículo |
| closedAccess |  | 15-jun-2007 | The Total Synthesis and Biological Properties of the Cytotoxic Macrolide FD-891 and Its Non-Natural (Z)-C12 Isomer | García-Fortanet, Jorge; Murga, Juan; Carda, Miguel; Marco, J. Alberto; Matesanz, Ruth CSIC ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC | artículo |
| openAccess |  | nov-2011 | Thermodynamics as a Tool for the Optimization of Drug Binding, Thermodynamics - Interaction Studies - Solids, Liquids and Gases | Matesanz, Ruth CSIC ; Pera, Benet CSIC; Díaz, José Fernando CSIC ORCID | capítulo de libro |
| openAccess |  | 22-jun-2017 | Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin | Sáez-Calvo, Gonzalo CSIC; Balaguer, Francisco de Asís CSIC ORCID; Barasoain, Isabel CSIC ; Rodríguez-Salarichs, Javier CSIC; Muñoz-Hernández, Hugo CSIC ORCID; Berbís, Manuel Álvaro CSIC; Peñalva, Miguel Ángel CSIC ORCID ; Matesanz, Ruth CSIC ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID | artículo |
| openAccess |  | 22-jun-2012 | Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubules | Field, Jessica J.; Pera, Benet CSIC; Calvo, Enrique; Canales, Ángeles CSIC ORCID; Zurwerra, Didier; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier CSIC; Matesanz, Ruth CSIC ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID | artículo |
