| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| openAccess | | ene-2023 | Chemical modulation of microtubule structure as a tool to target different diseases | Estévez-Gallego, Juan CSIC ORCID ; Álvarez-Bernad, Beatriz CSIC; Lucena-Agell, Daniel CSIC ORCID ; Bonato, Francesca CSIC ORCID; Giménez-Abián, Juan F. CSIC ; Blanco, Óscar; París, Rebeca; Fuertes, L.; Martínez, J. C.; Kamimura, Shinji; Gago, Federico CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID | comunicación de congreso |
| openAccess |  | 5-ene-2023 | Chemical modulation of microtubule structure through the laulimalide/peloruside site | Estévez-Gallego, Juan CSIC ORCID ; Álvarez-Bernad, Beatriz CSIC; Benet, Pera; Wullschleger, Christoph; Raes, Olivier; Menche, Dirk; Martínez, Juan Carlos; Lucena-Agell, Daniel CSIC ORCID ; Prota, Andrea E.; Bonato, Francesca CSIC ORCID; Bargsten, Katja; Cornelus, Jelle; Giménez-Abián, Juan F. CSIC ; Northcote, Peter; Steinmetz, Michel O.; Kamimura, Shinji; Altmann, Karl-Heinz; Paterson, Ian; Gago, Federico CSIC ORCID; Van der Eycken, Johan; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID | artículo |
| openAccess |  | 2018 | Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity | Bueno, Oskia CSIC; Tobajas, Gloria; Quesada, Ernesto CSIC ORCID ; Estévez-Gallego, Juan CSIC ORCID ; Noppen, Sam; Camarasa Rius, María José CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Liekens, Sandra; Priego, Eva María CSIC ORCID; Peréz-Pérez, María-Jesús CSIC ORCID | artículo |
| openAccess |  | 20-mar-2019 | Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands | Balaguer, Francisco de Asís CSIC ORCID; Mühlethaler, Tobias; Estévez-Gallego, Juan CSIC ORCID ; Calvo, Enrique; Giménez-Abián, Juan F. CSIC ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. CSIC ORCID ; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID | artículo |
| openAccess |  | 2021 | Crystal structures of taxane-tubulin complexes: Implications for the mechanism of microtubule stabilization by Taxol | Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Ma, Yuntao; Estévez-Gallego, Juan CSIC ORCID ; Roca, Carlos CSIC ORCID; Josa-Prado, Fernando CSIC ORCID; Goossens, Kenneth; Giménez-Abián, Juan F. CSIC ; Li, Shuo; Canales, Ángeles CSIC ORCID; Bargsten, Katja; Andreu, José Manuel CSIC ORCID ; Altmann, Karl-Heinz; Olieric, Natacha; Kamimura, Shinji; Mühlethaler, Tobias; Oliva, María A. CSIC ORCID ; Steinmetz, Michel O.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID | preprint |
| closedAccess |  | jun-2019 | Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the aT5 loop | Bueno, Oskia CSIC; Gargantilla, Marta CSIC ORCID; Estévez-Gallego, Juan CSIC ORCID ; Martins, Solange; Díaz, José Fernando CSIC ORCID ; Camarasa Rius, María José CSIC ORCID; Liekens, Sandra; Peréz-Pérez, María-Jesús CSIC ORCID ; Priego, Eva María CSIC ORCID | artículo |
| openAccess |  | 2018 | High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design | Bueno, Oskia CSIC; Estévez-Gallego, Juan CSIC ORCID ; Martins, S.; Prota, Andrea E.; Gago, Federico CSIC ORCID; Gómez-SanJuan, Asier CSIC; Camarasa Rius, María José CSIC ORCID; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID ; Peréz-Pérez, María-Jesús CSIC ORCID ; Liekens, Sandra; Priego, Eva María CSIC ORCID | artículo |
| openAccess |  | 16-dic-2021 | Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes | Rai, Ankit; Liu, Tianyang; Katrukha, Eugene A.; Estévez-Gallego, Juan CSIC ORCID ; Manka, Szymon W.; Paterson, Ian; Díaz, José Fernando CSIC ORCID ; Kapitein, Lukas C.; Moores, Carolyn A.; Akhmanova, Anna | artículo |
| openAccess |  | 3-jun-2017 | Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions. | Tang, Yong; Rodríguez-Salarichs, Javier CSIC; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuo | artículo |
| openAccess |  | 2020 | On the Importance of the Thiazole Nitrogen in Epothilones: Semisynthesis and Microtubule-Binding Affinity of Deaza-Epothilone C | Edenharter, Adriana; Ryckewaert, Lucie; Cintulová, Daniela; Estévez-Gallego, Juan CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
| openAccess |  | 23-ene-2018 | Protein-ligand complex for structure-based design: impact on the affinity and antitumor activity of new tubulin ligands | Bueno, Oskia CSIC; Estévez-Gallego, Juan CSIC ORCID ; Martins, S.; Prota, Andrea E.; Gago, Federico CSIC ORCID; Gómez-SanJuan, Asier CSIC; Camarasa Rius, María José CSIC ORCID; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID ; Liekens, Sandra; Peréz-Pérez, María-Jesús CSIC ORCID ; Priego, Eva María CSIC ORCID | comunicación de congreso |
| openAccess |  | 6-mar-2023 | Structural insight into the stabilization of microtubules by taxanes | Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Ma, Yuntao; Estévez-Gallego, Juan CSIC ORCID ; Li, Shuo; Bargsten, Katja; Josa-Prado, Fernando CSIC ORCID; Altmann, Karl-Heinz; Gaillard, Natacha; Kamimura, Shinji; Mühlethaler, Tobias; Gago, Federico CSIC ORCID; Oliva, María A. CSIC ORCID ; Steinmetz, Michel O.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID | artículo |
| openAccess |  | 10-mar-2020 | Structural model for differential cap maturation at growing microtubule ends | Estévez-Gallego, Juan CSIC ORCID ; Josa-Prado, Fernando CSIC ORCID; Ku, Siou; Martínez Buey, Rubén CSIC ORCID; Balaguer, Francisco de Asís CSIC ORCID; Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Kamma-Lorger, C.S.; Yagi, Toshiki; Iwamoto, Hiroyuki; Duchesne, Laurence; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Chrétien, Denis; Kamimura, Shinji; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID | artículo |
| closedAccess |  | 2016 | Targeting the colchicine site in tubulin through cyclohexanedione derivatives | Canela, María-Dolores CSIC; Bueno, Oskia CSIC; Noppen, Sam; Sáez-Calvo, Gonzalo CSIC; Estévez-Gallego, Juan CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Camarasa Rius, María José CSIC ORCID; Liekens, Sandra; Peréz-Pérez, María-Jesús CSIC ORCID ; Priego, Eva María CSIC ORCID | artículo |
| closedAccess |  | mar-2020 | Taxanes convert regions of perturbed microtubule growth into rescue sites | Rai, Ankit; Liu, Tianyang; Glauser, Simon; Katrukha, Eugene A.; Estévez-Gallego, Juan CSIC ORCID ; Rodríguez-García, Ruddi; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.; Altmann, Karl-Heinz; Kapitein, Lukas C.; Moores, Carolyn A.; Akhmanova, Anna | artículo |
| openAccess |  | 12-oct-2017 | Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sites | Field, Jessica J.; Pera, Benet CSIC; Estévez-Gallego, Juan CSIC ORCID ; Rodríguez-Salarichs, Javier CSIC; Sáez-Calvo, Gonzalo CSIC; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID | artículo |
