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openAccessraloxifene_n-Acetylcysteine_ameliorate_epidermolysis_bullosa.pdf.jpg16-sep-2020Raloxifene and n-acetylcysteine ameliorate TGF-signalling in fibroblasts from patients with recessive dominant epidermolysis bullosaAguado, Tania CSIC ORCID; García, Marta; García, Adela; Ferrer-Mayorga, Gemma CSIC; Martínez-Santamaría, Lucía; Río, Marcela del; Botella, Luisa María CSIC ORCID ; Sánchez-Puelles, José María CSIC ORCID artículo
closedAccessabr-2010Reduced plasma levels of Ang-2 and sEng as novel biomarkers in Hereditary Hemorrhagic Telangiectasia (HHT)Ojeda-Fernández, María Luisa CSIC; Barrios, Laura CSIC ORCID; Rodríguez-Barbero, Alicia; Recio-Poveda, Lucía ; Bernabéu, Carmelo CSIC ORCID ; Botella, Luisa María CSIC ORCID artículo
openAccess13023_2017_Article_664.pdf.jpg29-jun-2017Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau diseaseAlbiñana, Virginia CSIC; Jiménez Escribano, Rosa María; Soler, Isabel; Rodríguez Padial, Luis; Recio-Poveda, Lucía ; Villar Gómez de las Heras, Karina; Botella, Luisa María CSIC ORCID artículo
openAccessfgene_C. Bernabeu_2015.pdf.jpg31-mar-2015Research on potential biomarkers in hereditary hemorrhagic telangiectasiaBotella, Luisa María CSIC ORCID ; Albiñana, Virginia CSIC; Ojeda-Fernández, María Luisa CSIC; Recio-Poveda, Lucía ; Bernabéu, Carmelo CSIC ORCID artículo
openAccessReview_Albiñana_Art2020.pdf.jpg2020Review of Pharmacological Strategies with Repurposed Drugs for Hereditary Hemorrhagic Telangiectasia Related BleedingAlbiñana, Virginia CSIC; Cuesta, Ángel M. CSIC ORCID ; Rojas-P, Isabel de CSIC; Gallardo-Vara, Eunate CSIC ORCID; Recio-Poveda, Lucía ; Bernabéu, Carmelo CSIC ORCID ; Botella, Luisa María CSIC ORCID artículo
openAccessJ. Biol. Chem.-1998-Letamend__a-33011-9.pdf.jpg4-dic-1998Role of endoglin in cellular responses to transforming growth factor-beta. A comparative study with betaglycanLetamendía, Ainhoa CSIC; Lastres, Pedro ; Botella, Luisa María CSIC ORCID ; Raab, Ulla; Langa, Carmen CSIC; Velasco, Beatriz CSIC; Attisano, Liliana; Bernabéu, Carmelo CSIC ORCID artículo
openAccess13023_2018_Article_982.pdf.jpg4-feb-2019Safety of thalidomide and bevacizumab in patients with hereditary hemorrhagic telangiectasiaBuscarini, Elisabetta; Botella, Luisa María CSIC ORCID ; Geisthoff, Urban; Kjeldsen, Anette D.; Mager, Hans J.; Pagella, Fabio; Suppressa, Patrizia; Zarrabeitia, Roberto; Dupuis-Girod, Sophie; Shovlin, Claire L.artículo
openAccessjcm-10-01884.pdf.jpg27-abr-2021SARS-CoV-2 Infection in Hereditary Hemorrhagic Telangiectasia Patients Suggests Less Clinical Impact Than in the General PopulationMarcos, Sol; Albiñana, Virginia CSIC; Recio-Poveda, Lucía ; Tarazona, Belisa; Verde-González, María Patrocinio; Ojeda-Fernández, María Luisa CSIC; Botella, Luisa María CSIC ORCID artículo
openAccessjcm_marcos_2021.pdf.jpg27-ago-2021Sclerotherapy on demand with polidocanol to treat HHT nosebleedsMarcos, Sol; Botella, Luisa María CSIC ORCID ; Albiñana, Virginia CSIC; Arbia, Agustina; De Rosales, Anna Maríaartículo
openAccessInt. J. Cardiology_Luisa Botella_2016.pdf.jpg1-sep-2016Screening pulmonary arteriovenous malformations in a large cohort of Spanish patients with hemorrhagic hereditary telangiectasiaParra, José A.; Cuesta, José María; Zarrabeitia, Roberto; Fariñas-Álvarez, Concepción; Bueno, Jesús; Marqués, Sarah; Parra-Fariñas, Carmen; Botella, Luisa María CSIC ORCID ; Bernabéu, Carmelo CSIC ORCID ; Zarauza, Jesúsartículo
openAccessdmm_Gallardo-Vara_2018.pdf.jpg14-ago-2018Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasiaGallardo-Vara, Eunate CSIC ORCID; Tual-Chalot, Simon; Botella, Luisa María CSIC ORCID ; Arthur, Helen M.; Bernabéu, Carmelo CSIC ORCID artículo
openAccessJ. Biol. Chem.-2001-Sánchez-Elsner-38527-35.pdf.jpg19-oct-2001Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expressionSánchez-Elsner, Tilman CSIC ORCID; Botella, Luisa María CSIC ORCID ; Velasco, Beatriz CSIC; Corbí, Angel L. ; Attisano, Liliana; Bernabéu, Carmelo CSIC ORCID artículo
openAccessjcm_álvarez-hernández_2023.pdf.jpg29-nov-2023Tacrolimus as a promising drug for epistaxis and gastrointestinal bleeding in HHTÁlvarez-Hernández, Paloma; Patier, José-Luis; Marcos, Sol; Gómez del Olmo, Vicente; Lorente-Herraiz, Laura; Recio-Poveda, Lucía ; Botella, Luisa María CSIC ORCID ; Viteri-Noël, Adrián; Albiñana, Virginia CSICartículo
openAccessβ2-adrenergic_Von_Hippel–Lindau_disease.pdf.jpg25-ago-2020Targeting β2-adrenergic receptors shows therapeutical benefits in clear cell renal cell carcinoma from Von Hippel–Lindau diseaseAlbiñana, Virginia CSIC; Gallardo-Vara, Eunate CSIC ORCID; Rojas-P, Isabel de CSIC; Recio-Poveda, Lucía ; Aguado, Tania CSIC ORCID; Canto-Cano, Ana; Aguirre, Daniel T.; Serra, Marcelo M.; González-Peramato, Pilar; Martínez-Piñeiro, Luis; Cuesta, Ángel M. CSIC ORCID ; Botella, Luisa María CSIC ORCID artículo
openAccessBiochemical Journal_Botella_2009.pdf.jpg15-abr-2009TGF-beta regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3-Sp1-KLF6 interactionBotella, Luisa María CSIC ORCID ; Sanz-Rodríguez, Francisco CSIC ORCID; Komi, Yusuke; Fernandez-Lopez, Africa CSIC; Varela, Elisa; Garrido-Martin, Eva M. CSIC; Narla, Goutham; Friedman, Scott L.; Kojima, Soichiartículo
openAccessThe Endothelial Landscape_Rojas_PV_Art2021.pdf.jpg2021The endothelial landscape and its role in von hippel–lindau diseaseRojas-P, Isabel de CSIC; Albiñana, Virginia CSIC; Taranets, Lyudmyla; Recio-Poveda, Lucía ; Cuesta, Ángel M. CSIC ORCID ; Popov, Nikita; Kronenberger, Thales; Botella, Luisa María CSIC ORCID artículo
openAccessijms_cuesta_2022.pdf.jpg11-abr-2022The role of propranolol as a repurposed drug in rare vascular diseasesCuesta, Ángel M. CSIC ORCID ; Gallardo-Vara, Eunate CSIC ORCID; Casado-Vela, Juan CSIC ORCID CVN; Recio-Poveda, Lucía ; Botella, Luisa María CSIC ORCID ; Albiñana, Virginia CSICartículo
openAccessScientific Reports_Cuesta_2019.pdf.jpg11-jul-2019The β2-adrenergic receptor antagonist ICI-118,551 blocks the constitutively activated HIF signalling in hemangioblastomas from von Hippel-Lindau diseaseCuesta, Ángel M. CSIC ORCID ; Albiñana, Virginia CSIC; Gallardo-Vara, Eunate CSIC ORCID; Recio-Poveda, Lucía ; de Rojas, I.; Villar Gómez de las Heras, Karina; Aguirre, Daniel T.; Botella, Luisa María CSIC ORCID artículo
openAccessth_2007-97-2_7758.pdf.jpgfeb-2007Therapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT): Regulation of ALK-1/endoglin pathway in endothelial cellsFernandez-Lopez, Africa CSIC; Garrido-Martin, Eva M. CSIC; Sanz-Rodríguez, Francisco CSIC ORCID; Ramírez, José Ramón; Morales-Angulo, Carmelo; Zarrabeitia, Roberto; Pérez-Molino, Alfonso; Bernabéu, Carmelo CSIC ORCID ; Botella, Luisa María CSIC ORCID artículo
openAccessTH Open_Albiñana_2019 .pdf.jpg2019Topically applied etamsylate: a new orphan drugfor HHT-derived epistaxis (antiangiogenesisthrough FGF pathway inhibition)Albiñana, Virginia CSIC; Giménez-Gallego, Guillermo CSIC; García-Mato, Ángela CSIC ORCID; Palacios, Patricia; Recio-Poveda, Lucía ; Cuesta, Ángel M. CSIC ORCID ; Patier, José-Luis; Botella, Luisa María CSIC ORCID artículo