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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| openAccess |  | 26-nov-2020 | Glutathione metabolism is essential for self-renewal and chemoresistance of pancreatic cancer stem cells | Jagust, Petra; Alcalá, Sonia CSIC ORCID; Sainz, Bruno Jr. ; Heeschen, Christopher; Sancho, Patricia CSIC ORCID | artículo |
| openAccess |  | 2017 | Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling | Hohwieler, Meike; Illing, Anett; Hermann, Patrick C.; Mayer, Tobias; Stockmann, Marianne; Perkhofer, Lukas; Eiseler, Tim; Antony, Justin S.; Müller, Martin; Renz, Susanne; Kuo, Chao-Chung; Lin, Qiong; Sendler, Matthias; Breunig, Markus; Kleiderman, Susanne M.; Lechel, André; Zenker, Martin; Leichsenring, Michael; Rosendahl, Jonas; Zenke, Martin; Sainz, Bruno Jr. ; Mayerle, Julia; Costa, Ivan G.; Seufferlein, Thomas; Kormann, Michael; Wagner, Martin; Liebau, Stefan; Kleger, Alexander | artículo |
| openAccess |  | 4-jul-2020 | Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells | Cash, Timothy P.; Alcalá, Sonia CSIC ORCID; Rico-Ferreira, María del Rosario; Hernández Encinas, María Elena CSIC; García, Jennifer; Albarrán, María Isabel; Valle, Sandra; Muñoz, Javier ; Martínez-González, Sonia; Blanco-Aparicio, Carmen; Pastor, Joaquín; Serrano, Manuel; Sainz, Bruno Jr. | artículo |
| openAccess |  | 2020 | ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity | Alcalá, Sonia CSIC ORCID; Sancho, Patricia CSIC ORCID; Martinelli, Paola; Navarro, Diego CSIC; Pedrero García, Coral; Martin-Hijano, Laura; Valle, Sandra; Earl, Julie; Rodríguez-Serrano, Macarena; Ruiz-Cañas, Laura CSIC ORCID; Rojas, Katerin; Carrato, Alfredo; García-Bermejo, María Laura; Fernández-Moreno, Miguel Ángel CSIC ORCID; Hermann, Patrick C.; Sainz, Bruno Jr. | artículo |
| openAccess |  | 2022 | LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer | Delle Cave, Donatella; Buonaiuto, Silvia; Sainz, Bruno Jr. ; Fantuz, Marco; Mangini, María; Carrer, Alessandro; Domenico, Annalisa Di; Lavazzo, Tea Teresa; Andolfi, Gennaro; Cortina, Carme; Sevillano, Marta; Heeschen, Christopher; Colonna, Vincenza; Corona, Marco; Cucciardi, Antonio; Guida, Martina Di; Batlle, Eduard; Luca, Annachiara De; Lonardo, Enza | artículo |
| closedAccess |  | ene-2019 | Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice | Görgülü, Kivanc; Diakopoulos, Kalliope N.; Ai, Jiaoyu; Schoeps, Benjamin; Kabacaoglu, Derya; Karpathaki, Angeliki F.; Ciecielski, Katrin J.; Kaya-Aksoy, Ezgi; Ruess, Dietrich A.; Berninger, Alexandra; Kowalska, Marlena; Stevanovic, Marija; Wörmann, Sonja M.; Wartmann, Thomas; Zhao, Yue; Halangk, Walter; Voronina, Svetlana; Tepikin, Alexey; Schlitter, Anna Melissa; Steiger, Katja; Artati, Anna; Adamski, Jerzy; Aichler, Michaela; Walch, Axel; Jastroch, Martin; Hartleben, Götz; Mantzoros, Christos S.; Weichert, Wilko; Schmid, Roland M.; Herzig, Stephan; Krüger, Achim; Sainz, Bruno Jr. ; Lesina, Marina; Algül, Hana | artículo |
| openAccess |  | 2022 | Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma | Alonso-Nocelo, Marta; Ruiz-Cañas, Laura CSIC ORCID; Sancho, Patricia CSIC ORCID; Alcalá, Sonia CSIC ORCID; Pedrero García, Coral; Vallespinós, Mireia CSIC; López-Gil, Juan Carlos CSIC; Ochando, Marina; García-García, Elena; Trabulo, Sara María David; Martinelli, Paola; Sánchez-Tomero, Patricia; Sánchez-Palomo, Carmen; González-Santamaría, Patricia; Yuste Pérez, Lourdes CSIC; Wörmann, Sonja M.; Kabacaoglu, Derya; Earl, Julie; Martín, Alberto CSIC ORCID; Salvador, Fernando CSIC; Valle, Sandra; Martin-Hijano, Laura; Carrato, Alfredo; Erkan, Mert M.; García-Bermejo, María Laura; Hermann, Patrick C.; Algül, Hana; Moreno-Bueno, Gema CSIC ORCID; Heeschen, Christopher; García del Portillo, Francisco CSIC ORCID ; Cano, Amparo CSIC; Sainz, Bruno Jr. | artículo |
| openAccess |  | 2019 | MEK inhibition targets cancer stem cells and impedes migration of pancreatic cancer cells in vitro and in vivo | Walter, Karolin; Tiwary, Kanishka; Trajkovic-Arsic, Marija; Hidalgo-Sastre, Ana; Dierichs, Laura; Liffers, Sven T.; Gu, Jiangning; Gout, Johann; Schulte, Lucas-Alexander; Münch, Jan; Seufferlein, Thomas; Sainz, Bruno Jr. ; Siveke, Jens T.; Rodriguez-Aznar, Eva; Hermann, Patrick C. | artículo |
| openAccess |  | 2020 | Modeling cancer using zebrafish xenografts: Drawbacks for mimicking the human microenvironment | Cabezas-Sainz, Pablo; Pensado-López, Alba; Sainz, Bruno Jr. ; Sánchez, Laura | artículo |
| openAccess |  | 2018 | Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase | Ruess, Dietrich A.; Heynen, Guus J.; Ciecielski, Katrin J.; Ai, Jiaoyu; Berninger, Alexandra; Kabacaoglu, Derya; Görgülü, Kivanc; Dantes, Zhara; Wörmann, Sonja M.; Diakopoulos, Kalliope N.; Karpathaki, Angeliki F.; Kowalska, Marlena; López-Alberca, María P.; Nazaré, Marc; Reichert, Maximilian; Saur, Dieter; Erkan, Mert M.; Hopt, Ulrich T.; Sainz, Bruno Jr. ; Birchmeier, Walter; Schmid, Roland M.; Lesina, Marina; Algül, Hana | artículo |
| openAccess |  | 2018 | Pancreatic cancer stem cells: A state or an entity? | Hermann, Patrick C.; Sainz, Bruno Jr. | artículo |
| openAccess |  | 2020 | Pancreatic cancer-derived organoids – a disease modeling tool to predict drug response | Frappart, Pierre-Olivier; Walter, Karolin; Gout, Johann; Beutel, Alica K.; Morawe, Mareen; Arnold, Frank; Breunig, Markus; Barth, Thomas F. E.; Marienfeld, Ralf; Schulte, Lucas-Alexander; Ettrich, Thomas; Hackert, Thilo; Svinarenko, Michael; Rösler, Reinhild; Wiese, Sebastian; Wiese, Heike; Perkhofer, Lukas; Müller, Martin; Lechel, André; Sainz, Bruno Jr. ; Hermann, Patrick C.; Seufferlein, Thomas; Kleger, Alexander | artículo |
| openAccess |  | 2020 | Partial complementation between the immediate early proteins ICP4 of herpes simplex virus type 1 and IE180 of pseudorabies virus | Lerma, L.; Muñoz, A. L.; García Utrilla, R.; Sainz, Bruno Jr. ; Tabarés, E.; Gómez Sebastián, Silvia | artículo |
| openAccess |  | 2018 | Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder | Friederich, Marisa W.; Timal, Sharita; Powell, Christopher A.; Dallabona, Cristina; Kurolap, Alina; Palacios-Zambrano, Sara; Bratkovic, Drago; Derks, Terry G. J.; Bick, David; Bouman, Katelijne; Chatfield, Kathryn C.; Damouny-Naoum, Nadine; Dishop, Megan K.; Falik-Zaccai, Tzipora C.; Fares, Fuad; Fedida, Ayalla; Ferrero, Ileana; Gallagher, Renata C.; Garesse, Rafael CSIC ORCID; Gilberti, Micol; Gónzalez, Cristina; Gowan, Katherine; Habib, Clair; Halligan, Rebecca K.; Kalfon, Limor; Knight, Kaz; Lefeber, Dirk; Mamblona, Laura; Mandel, Hanna; Mory, Adi; Ottoson, John; Paperma, Tamar; Prujin, Ger J. M.; Rebelo-Guiomar, Pedro F.; Saada, Ann; Sainz, Bruno Jr. ; Salvemini, Hayley; Schoots, Mirthe H.; Smeitink, Jan A.; Szukszto, Maciej J.; Horst, Hendrik J. ter; Brandt, Frans van den; Spronsen, Francjan J. van; Veltman, Joris A.; Wartchow, Eric; Wintjes, Liesbeth T.; Zohar, Yaniv; Fernández-Moreno, Miguel Ángel CSIC ORCID; Baris, Hagit N.; Donnini, Claudia; Minczuk, Michal; Rodenburg, Richard J.; Van Hove, Johan L.K. | artículo |
| openAccess |  | 2017 | Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells | Luciene da Silva, Istéfani; Montero, Lucía; Martín-Villar, Ester CSIC ORCID; Martín-Pérez, Jorge CSIC ORCID ; Sainz, Bruno Jr. ; Renart, Jaime CSIC ORCID; Toscano Simões, Renata; Soares Veloso, Emerson; Salviano Teixeira, Cláudia; Oliveira, Mônica C. de; Ferreira, Enio; Quintanilla, Miguel CSIC ORCID | artículo |
| closedAccess |  | 6-feb-2018 | Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors | Djurec, Magdolna; Graña, Osvaldo; Lee, Albert; Troulé, Kevin; Espinet, Elisa; Cabras, Lavinia; Navas, Carolina; Blasco, María Teresa; Martín-Díaz, Laura; Burdiel, Miranda CSIC; Li, Jing; Liu, Zhaoqi; Vallespinós, Mireia CSIC; Sánchez-Bueno, Francisco; Sprick, Martin R.; Trumpp, Andreas; Sainz, Bruno Jr. ; Al-Shahrour, Fátima; Rabadán, Raúl; Guerra, Carmen CSIC; Barbacid, Mariano CSIC | artículo |
| openAccess |  | 2021 | Somatic Mutation Profiling in the Liquid Biopsy and Clinical Analysis of Hereditary and Familial Pancreatic Cancer Cases Reveals KRAS Negativity and a Longer Overall Survival | Earl, Julie; Barreto, Emma; Castillo, María E.; Fuentes, Raquel; Rodríguez-Garrote, Mercedes; Ferreiro, Reyes; Reguera, Pablo; Muñoz, Gloria; García-Seisdedos, David; Sainz, Bruno Jr. ; Malats, Núria; Carrato, Alfredo | artículo |
| openAccess | | 2020 | Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer | Gout, Johann; Perkhofer, Lukas; Morawe, Mareen; Arnold, Frank; Ihle, Michaela; Biber, Stephanie; Lange, Sebastian; Roger, Elodie; Kraus, Johann M.; Stifter, Katja; Hahn, Stephan A.; Zamperone, Andrea; Engleitner, Thomas; Müller, Martin; Walter, Karolin; Rodriguez-Aznar, Eva; Sainz, Bruno Jr. ; Hermann, Patrick C.; Hessmann, Elisabeth; Müller, Sebastian; Azoitei, Ninel; Lechel, André; Liebau, Stefan; Wagner, Martin; Simeone, Diane M.; Kestler, Hans A.; Seufferlein, Thomas; Wiesmüller, Lisa; Rad, Roland; Frappart, Pierre-Olivier; Kleger, Alexander | artículo |
| openAccess |  | 2022 | Targeting BPTF sensitizes pancreatic ductal adenocarcinoma to chemotherapy by repressing ABC-Transporters and impairing multidrug resistance (MDR) | Muñoz Velasco, Raúl; Jiménez Sánchez, Paula; García García, Ana; Blanco Martinez-Illescas, Raquel; Pastor Senovilla, Ángela; Lozano Yagüe, Marian; Trento, Alfonsina; García-Martin, Rosa María; Navarro, Diego CSIC; Sainz, Bruno Jr. ; Rodríguez Peralto, José Luis; Sánchez-Arévalo Lobo, Víctor J. | artículo |
| openAccess |  | 2020 | Targeting MAD2 modulates stemness and tumorigenesis in human Gastric Cancer cell lines | Pajuelo-Lozano, Natalia CSIC; Alcalá, Sonia CSIC ORCID; Sainz, Bruno Jr. ; Perona Abellón, Rosario CSIC ORCID; Sánchez-Pérez, Isabel CSIC ORCID | artículo |
