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openAccessC5MB00852B_postprint.pdf.jpg22-Apr-20163-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells.Ordóñez, Yadira F.; González, Jèssica; Bedia, Carmen CSIC ORCID; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio; Fabriàs, Gemma CSIC ORCID artículo
openAccess1985A convenient and stereoselective synthesis of (3Z,5Z)-5-fluoro-tetradecadien-1-yl acetate a fluorinated analog of the sex pheromone of the carpenterworm Prionoxistus robiniae (Peck)Alcázar, A.; Camps, Francesc; Coll Toledano, Josep; Fabriàs, Gemma CSIC ORCID ; Guerrero, Ángel CSIC ORCIDartículo
openAccessA Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor.pdf.jpg17-Jan-2020A Mechanism-Based Sphingosine-1-phosphate Lyase InhibitorPons, Guillem; Riba, Daniel; Casasampere, Mireia; Izquierdo, Eduardo; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Rodríguez Ortega, Pilar G.; Montejo, Manuel; López González, Juan J.; Casas, Josefina CSIC ORCID ; Delgado Cirilo, Antonioartículo
closedAccess2010A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber diseaseBedia, Carmen CSIC ORCID; Camacho, Luz CSIC ORCID; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Levade, Thierryartículo
openAccessAcid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities.pdf.jpg1-Apr-2017Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System AbnormalitiesSikora, Jakub; Casas, Josefina CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Walkley, Steven U.artículo
closedAccess2011Acid Ceramidase Expression Modulates the Sensitivity of A375 Melanoma Cells to DacarbazineBedia, Carmen CSIC ORCID; Casas, Josefina CSIC ORCID ; Andrieu-Abadie, Nathalie; Fabriàs, Gemma CSIC ORCID ; Levade, Thierryartículo
openAccess1-s2.0-S2213231721002111-main.pdf.jpgSep-2021Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulationTorres, Sandra CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Matías, Nuria CSIC; Insausti, Naroa CSIC ORCID; Castro, Fernanda; Casasempere, Mireia; Fabriàs, Gemma CSIC ORCID ; Casas, Josefina CSIC ORCID ; Enrich, Carlos; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
openAccess2125814_B1.pdf.jpg16-Nov-1999Ácidos grasos α-halogenados y sus derivados como inhibidores de la producción de feromonas sexuales de insectosCamps Díez, Francisco CSIC; Fabriàs, Gemma CSIC ORCID ; Hernanz Redondo, Davidpatente
openAccessActivity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiols.pdf.jpg1-Oct-2015Activity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiolsCasasampere, Mireia; Camacho, Luz CSIC ORCID; Casas, Josefina CSIC ORCID ; Cingolani, Francesca; Egido-Gabás, Meritxell CSIC; Abad, José Luis CSIC ORCID ; Bedia, Carmen CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
openAccess28-Apr-2019Activity-Based Imaging of Acid Ceramidase in Living CellsOrdóñez, Yadira F.; Abad, José Luis CSIC ORCID ; Aseeri, Mazen; Casas, Josefina CSIC ORCID ; Garcia, Virginie; Casasampere, Mireia; Schuchman, Edward H.; Levade, Thierry; Delgado Cirilo, Antonio; Triola Guillem, Gemma CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
openAccessES2396092A1.pdf.jpg19-Feb-2013Amidas de 2-amino-1,3-propanodioles y su uso como inhibidores de ceramidasasAbad, José Luis CSIC ORCID ; Camacho, Luz CSIC ORCID; Casas, Josefina CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Garrido, María; Thomson, Timothy M. CSIC ORCID ; Meca-Cortés, Óscar CSIC ORCID; Delgado Cirilo, Antoniosolicitud de patente
openAccessWO2013004871A1.pdf.jpg10-Jan-2013Amides of 2-amino-1,3-propanediols and use thereof as ceramidase inhibitorsAbad, José Luis CSIC ORCID ; Camacho, Luz CSIC ORCID; Casas, Josefina CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Garrido, María; Thomson, Timothy M. CSIC ORCID ; Meca-Cortés, Óscar CSIC ORCID; Delgado Cirilo, Antoniopatente
closedAccessBedia_Carmen_et_al.pdf.jpg8-Sep-2005Analogs of the dihydroceramide desaturase inhibitor GT11 modified at the amide function: synthesis and biological activitiesBedia, Carmen CSIC ORCID; Triola Guillem, Gemma CSIC ORCID; Casas, Josefina CSIC ORCID ; Llebaria, Amadeu CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
openAccess1983Anomalous formation of 1,1,4-tribromohex-1-en-3-one in the wittig reaction of 2-halopent-2-enals with dibromomethylene triphenylphosphoraneCamps, Francesc; Coll, J.; Fabriàs, Gemma CSIC ORCID ; Guerrero, Ángel CSIC ORCID; Riba, M.artículo
openAccess10-Oct-1994Behavior of the processionary moth to the sex pheromone and analogues in the laboratory. Search for a new minor component of the pheromoneQuero, Carmen CSIC ORCID ; Malo, E.; Fabriàs, Gemma CSIC ORCID ; Camps, Francesc; Guerrero, Ángel CSIC ORCIDactas de congreso
closedAccess20-May-2006Biosynthesis of 10,12-dienoic fatty acids by a bifunctional Delta11 desaturase in Spodoptera littoralisSerra, Montserrat; Piña, Benjamín CSIC ORCID ; Bujons Vilàs, Jordi; Camps Díez, Francisco CSIC; Fabriàs, Gemma CSIC ORCID artículo
openAccessCCR5 deficiency impairs CD4+ T-cell memory.pdf.jpg11-Jun-2020CCR 5 deficiency impairs CD 4+ T‐cell memory responses and antigenic sensitivity through increased ceramide synthesisMartín‐Leal, Ana; Blanco, Raquel; Casas, Josefina CSIC ORCID ; Sáez, María Eugenia; Rodríguez‐Bovolenta, Elena; de Rojas, Itziar; Drechsler, Carina; Real, Luis Miguel CSIC ORCID; Fabriàs, Gemma CSIC ORCID ; Ruíz, Agustín; Castro, Mario; Schame, Wolfgang WA; Alarcón, Balbino CSIC ORCID; Van Santen, Hisse M; Mañes, Santosartículo
openAccessVanSantenHM_CCR5deficiency.pdf.jpg11-Jun-2020CCR5 deficiency impairs CD4+ T-cell memory responses and antigenic sensitivity through increased ceramide synthesisMartín-Leal, Ana; Blanco, Raquel; Casas, Josefina CSIC ORCID ; Sáez, María Eugenia; Rodríguez-Bovolenta, Elena; de Rojas, Itziar; Drechsler, Carina; Real, Luis M.; Fabriàs, Gemma CSIC ORCID ; Ruíz, Agustín; Castro, Mario; Schamel, Wolfgang W.A.; Alarcón, Balbino CSIC ORCID; Van Santen, Hisse M; Mañes, Santosartículo
openAccess1-s2.0-S0022202X15354865-main.pdf.jpg2012Cellular changes that accompany shedding of human corneocytesLin, T.-K.; Crumrine, D.; Ackerman, L.D.; Santiago, J.-L.; Roelandt, T.; Uchida, Y.; Hupe, M.; Fabriàs, Gemma CSIC ORCID ; Abad, José Luis CSIC ORCID ; Rice, R.H.; Elias, P.M.artículo
closedAccess2011Ceramidases in hematological malignancies: senseless or neglected target?Fabriàs, Gemma CSIC ORCID ; Bedia, Carmen CSIC ORCID; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonioartículo