Showing results 1 to 20 of 31
next >
| Rights | Preview | Issue Date | Title | Author(s) | Type |
| openAccess |  | 5-May-2011 | 1,8-Naphthyridine-devired compounds and the use thereof in the treatment of neurodegenerative diseases | Ríos Salgado, Cristóbal; Romero Martínez, Alejandro; Egea Maiquez, Javier; León, Rafael ; Villarroya Sánchez, Mercedes; García López, Manuela; García García, Antonio; Marco-Contelles, José CSIC ORCID; Soriano, Elena CSIC ORCID; Samadi, Abdelouahid CSIC ORCID; Chioua, Mourad CSIC ORCID | artículo |
| closedAccess |  | 2012 | Benzothiazepine CGP37157 and its isosteric 2′-ethyl analogue provide neuroprotection and block cell calcium entry | González-Lafuente, Laura; Egea, Javier; León, Rafael ; Martínez-Sanz, F. J.; Monjas, Leticia CSIC ORCID; Pérez, Concepción; Merino, Cristina; García-De Diego. Antonio M.; Rodríguez-Franco, María Isabel CSIC ORCID ; García, Antonio G.; Villarroya, Mercedes; Lopez, Manuela G.; Ríos, Cristóbal de los | artículo |
| openAccess |  | 1-Jun-2011 | Compuestos derivados de 1,8-naftiridinas y su uso en el tratamiento de enfermedades neurodegenerativas | Romero Martínez, Alejandro; García García, Antonio; García López, Manuela; Egea Maiquez, Javier; Chioua, Mourad CSIC ORCID ; Villarroya Sánchez, Mercedes; Soriano, Elena CSIC ORCID; León, Rafael ; Marco-Contelles, José CSIC ORCID; Ríos Salgado, Cristóbal; Samadi, Abdelouahid CSIC ORCID | solicitud de patente |
| openAccess |  | 2017 | Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease | Gameiro, Isabel; Michalska, Patrycja; Tenti, Giammarco; Cores, Ángel; Buendía Abaitua, Izaskun; Rojo, Ana I. CSIC ORCID; Georgakopoulos, Nikolaos D.; Hernández, Jesús M. CSIC ORCID ; Ramos, María Teresa; Wells, Geoffrey; López, Manuela G.; Cuadrado, Antonio CSIC ORCID; Menéndez, Carlos; León, Rafael | artículo |
| openAccess |  | 2017 | Enzymatic and solid-phase synthesis of new donepezil-based L- and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia | Monjas, Leticia CSIC ORCID; Arce, Mariana P. CSIC; León, Rafael ; Egea, Javier; Pérez, Concepción; Villarroya, Mercedes; Lopez, Manuela G.; Gil, Carmen ; Conde, Santiago; Rodríguez-Franco, María Isabel CSIC ORCID | artículo |
| openAccess |  | Sep-2020 | Geochemical behavior of rare earth elements in acid drainages: Modeling achievements and limitations | Lozano, Alba; Ayora, Carlos CSIC ORCID; Macías, Francisco; Gimeno, María José; León, Rafael ; Auqué, Luis | artículo |
| closedAccess |  | 21-May-2020 | Impact of KPC Production and High-Level Meropenem Resistance on All-Cause Mortality of Ventilator-Associated Pneumonia in Association with Klebsiella pneumoniae | Rivera-Espinar, Francisco; Machuca, Isabel; Tejero, Rocío; Rodríguez, Jorge; Mula, Ana; Marfil-Pérez, Eduardo; Cano, Ángela; Gutiérrez-Gutiérrez, Belén; Rodríguez, Marina; Pozo, Juan Carlos; Fuente, Carmen de la; Rodríguez-Baño, Jesús; Martínez-Martínez, Luis; León, Rafael ; Torre-Cisneros, Julián | artículo |
| closedAccess |  | 2020 | Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization | Michalska, Patrycja; Buendía Abaitua, Izaskun; Duarte, Pablo; Fernández-Mendívil, Cristina; Negredo, Pilar; Cuadrado, Antonio CSIC ORCID; López, Manuela G.; León, Rafael | artículo |
| embargoedAccess |  | May-2021 | Mine waters as a secondary source of rare earth elements worldwide: The case of the Iberian Pyrite Belt | León, Rafael ; Macías, Francisco; Cánovas, Carlos R.; Pérez-López, Rafael; Ayora, Carlos CSIC ORCID; Nieto, José Miguel; Olías, Manuel | artículo |
| closedAccess |  | 2021 | Monoamine Oxidase Inhibitors: from classic to new clinical approaches | Cuadrado, Antonio CSIC ORCID; León, Rafael | capítulo de libro |
| closedAccess |  | 2017 | Mortality Associated with Bacteremia Due to Colistin-Resistant Klebsiella pneumoniae with High-Level Meropenem Resistance: Importance of Combination Therapy without Colistin and Carbapenems | Machuca, Isabel; Gutiérrez-Gutiérrez, Belén; Gracia-Ahufinger, Irene; Rivera-Espinar, Francisco; Cano, Ángela; Guzmán-Puche, Julia; Pérez-Nadales, Elena; Natera, Clara; Rodríguez, Marina; León, Rafael ; Castón, Juan J.; Rodríguez-López, Fernando; Rodríguez-Baño, Jesús; Torre-Cisneros, Julián | artículo |
| openAccess |  | 2018 | Multitarget compounds for the treatment of neurodegenerative diseases: Nrf2-EpRE pathway as key target | Michalska, Patrycja; Buendía Abaitua, Izaskun; Duarte, Pablo; Luengo, Enrique; Fernández-Mendívil, Cristina; Morales-García, José A. CSIC ORCID; Pérez Castillo, Ana CSIC ORCID; García-López, Manuela; León, Rafael | comunicación de congreso |
| openAccess |  | 17-Jul-2020 | Multitarget Virtual Screening for Drug Repurposing in COVID19 | Sorzano, Carlos Óscar S.; Crisman, Enrique; Carazo, José M.; León, Rafael | artículo |
| closedAccess | | 2011 | N-Acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer’s disease | González Muñoz, Gema C.; Arce, Mariana P. CSIC; López, Beatriz; López, Beatriz; Romero, Alejandro CSIC ORCID; del Barrio, Laura; Martín de Saavedra, María Dolores; Egea, Javier; León, Rafael ; Villarroya, Mercedes; López, Manuela G.; García, Antonio G.; Conde, Santiago CSIC ORCID; Rodríguez-Franco, María Isabel CSIC ORCID | artículo |
| openAccess |  | 8-Jul-2019 | New neurogenic inducers with combined activities in key targets related to Alzheimer¿s disease | Herrera-Arozamena, Clara; Estrada-Valencia, M.; Pérez, C.; Viña, D.; Michalska, P.; León, Rafael ; López, M. G.; Morales-García, J. A.; Perez-Castillo, Amalia; Rodríguez-Franco, María Isabel CSIC ORCID | comunicación de congreso |
| openAccess | | 4-Nov-2019 | Non conventional targets for the treatment of Alzheimer's disease | López, M. G.; Luengo, E.; Trigo, P.; Fernández-Mendívil, Cristina; Franco, F.; Sastre, Eric del; Cuadrado, A.; Rodríguez-Franco, María Isabel CSIC ORCID ; León, Rafael | comunicación de congreso |
| closedAccess |  | 2013 | Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia | Lorrio, Silvia; Gómez-Rangel, Vanessa; Negredo, Pilar; Egea, Javier; León, Rafael ; Romero, Alejandro CSIC ORCID; Dal-Cim, Tharine.; Villarroya, Mercedes; Rodríguez-Franco, María Isabel CSIC ORCID ; Conde, Santiago CSIC ORCID; Arce, Mariana P. CSIC; Roda, José María; García, Antonio G.; López, Manuela G. | artículo |
| closedAccess |  | 2017 | Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices | Punzón, Eva; García-Alvarado, F.; Maroto, Marcos; Fernández-Mendívil, Cristina; Michalska, P.; García-Álvarez, Isabel; Arranz-Tagarro, J. A.; Buendía, Izaskun; López, M. G.; León, Rafael ; Gandía, Luis; Fernández-Mayoralas, Alfonso CSIC ORCID ; García, Antonio G. | artículo |
| openAccess |  | 3-Jul-2019 | Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury | Rubio-Navarro, Alfonso; Vázquez-Carballo, Cristina; Guerrero-Hue, Melania; García-Caballero, Cristina; Herencia, Carmen; Gutiérrez, Eduardo; Yuste, Claudia; Sevillano, Ángel; Praga, Manuel; Egea, Javier; Cannata, Pablo; Cortegano, Isabel CSIC ORCID; Andrés, Belén de; Gaspar, María Luisa; Cadenas, Susana; Michalska, Patrycja; León, Rafael ; Ortiz, Alberto; Egido, Jesús; Moreno, Juan Antonio | artículo |
| closedAccess |  | 2013 | Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease | León, Rafael ; Garcia, Antonio G.; Marco-Contelles, José CSIC ORCID | artículo |
