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closedAccessrestringido.pdf.jpgJan-20083HMG-CoA reductasa inhibitor, simvastatin, inhibits cell cycle progression at the G1-S checkpoint in immortalized lymphocytes from Alzheimer´s disease patients independently of cholesterol lowering effectsSala, Simone G.; Muñoz, Úrsula CSIC; Bartolomé Robledo, Fernando CSIC ORCID CVN; Bermejo-Pareja, Félix; Martín-Requero, Ángeles CSIC ORCID artículo
closedAccessJun-2010A megalin polymorphism associated with promoter activity and Alzheimer's disease riskVargas, Teo; Bullido, María Jesús CSIC ORCID; Martínez, Ana CSIC ORCID ; Antequera, Desiree; Clarimón, Jordi; Rosich-Estrago, Marcel; Martín-Requero, Ángeles CSIC ORCID ; Mateo, Ignacio; Rodríguez-Rodríguez, Eloy; Vilella-Cuadrada, Elisabet; Frank, Ana; Lleó, Alberto; Molina-Porcel, Laura; Blesa, Rafael; Combarros, Onofre; Gómez-Isla, Teresa; Bermejo-Pareja, Félix; Valdivieso Amate, Fernando; Carro, Evaartículo
openAccessCNS postprint 2018.pdf.jpg7-May-2018Activation of the cannabinoid type 2 receptor by a novel indazole derivative normalizes the survival pattern of lymphoblasts from patients with late-onset alzheimer’s diseaseDel Cerro, Patricia; Alquézar, Carolina CSIC ORCID; Bartolomé Robledo, Fernando CSIC ORCID CVN; González-Naranjo, Pedro CSIC ORCID; Pérez, Concepción; Carro, Eva; Páez, Juan A. CSIC ORCID; Campillo, Nuria E. CSIC ORCID ; Martín-Requero, Ángeles CSIC ORCID artículo
openAccessAlquezar_NBA_2012_33_2.pdf.jpgFeb-2012Alterations in cell cycle-related proteins in lymphoblasts from carries of the c.709-1G>A PGRN mutation associated with FTLD-TDP dementiaAlquézar, Carolina CSIC ORCID; Esteras, Noemí; Bartolomé Robledo, Fernando CSIC ORCID CVN; Merino, José J.; Alzualde, Ainhoa; López de Munain, Adolfo; Martín-Requero, Ángeles CSIC ORCID artículo
openAccessEsteras_Current_Alzh_Res_2012_9_3.pdf.jpgMar-2012Altered calmodulin degradation and signaling in non-neuronal cells from Alzheimer’s disease patientsEsteras, Noemí; Muñoz, Úrsula CSIC; Alquézar, Carolina CSIC ORCID; Bartolomé Robledo, Fernando CSIC ORCID CVN; Bermejo-Pareja, Félix; Martín-Requero, Ángeles CSIC ORCID artículo
closedAccessrestringido.pdf.jpgSep-2012Altered cell cycle-related gene expression in brain and lymphocytes from a transgenic mouse model of Alzheimer´s disease [amyloid precursor protein/presenilin 1 (PS1)]Esteras, Noemí; Bartolomé Robledo, Fernando CSIC ORCID CVN; Alquézar, Carolina CSIC ORCID; Antequera, Desiree; Muñoz, Úrsula CSIC; Carro, Eva; Martín-Requero, Ángeles CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2005Altered transcriptional regulators in response to serum in immortalized lympozytes from Alzheimer disease patientsDe las Cuevas, Natividad; Muñoz, Úrsula CSIC; García-Hermida, Ofelia ; Martín-Requero, Ángeles CSIC ORCID artículo
openAccessScientific Reports_Bartolome F._2018.pdf.jpg1-Mar-2018Author Correction: Pathogenic p62/ SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substratesBartolomé Robledo, Fernando CSIC ORCID CVN; Esteras, Noemí; Martín-Requero, Ángeles CSIC ORCID ; Boutoleau-Bretonnière, Claire; Vercelletto, Martine; Gabelle, Audrey; Ber, Isabelle Le; Honda, Tadashi; Dinkova-Kostova, Albena T.; Hardy, John A.; Carro, Eva; Abramov, Andrey Yurevichcorrigenda
closedAccessaccesoRestringido.pdf.jpg2003Ca2+/calmodulin-dependent modulation of cell cycle elements, pRb and p27kip1 involved in the enhanced proliferation of lymphoblasts from patients with Alzheimer dementiaDe las Cuevas, Natividad; Urcelay, Elena; García-Hermida, Ofelia ; Saíz-Diaz, Rosa A.; Bermejo-Pareja, Félix; Sánchez Ayuso, Matilde CSIC ORCID ; Martín-Requero, Ángeles CSIC ORCID artículo
openAccessalzrt219.pdf.jpg7-Nov-2013Calmodulin levels in blood cells as a potential biomarker of Alzheimer's diseaseEsteras, Noemí; Alquézar, Carolina CSIC ORCID; De la Encarnación, Ana; Villarejo, Alberto; Bermejo-Pareja, Félix; Martín-Requero, Ángeles CSIC ORCID artículo
openAccessEP3604310A1.pdf.jpg5-Feb-2020CDC-7-inhibitors compounds and use thereof for the treatment of neurological conditionsMartínez, Ana CSIC ORCID ; Pérez, Daniel I.; Gil, Carmen ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa; Martínez-González, Loreto CSIC ORCID CVN ; Pérez, Concepciónsolicitud de patente
openAccessWO2018172587A1.pdf.jpg27-Sep-2018CDC-7-inhibitors compounds and use thereof for the treatment of neurological conditionsMartinez Gil, Ana ; Pérez, Daniel I.; Gil, Carmen ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa; Martínez-González, Loreto CSIC ORCID CVN ; Pérez, Concepciónsolicitud de patente
openAccessUS2020093828A1.pdf.jpg26-Mar-2020CDC-7-inhibitors compounds and use thereof for the treatment of neurological conditionsMartínez, Ana CSIC ORCID ; Pérez, Daniel I.; Gil, Carmen ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa; Martínez-González, Loreto CSIC ORCID CVN; Pérez, Concepciónsolicitud de patente
closedAccessrestringido.pdf.jpgSep-2010Cell cycle and Alzheimer´s disease. Studies in non-neuronal cellsDe las Cuevas, Natividad; Muñoz, Úrsula CSIC; Bartolomé Robledo, Fernando CSIC ORCID CVN; Esteras, Noemí; Alquézar, Carolina CSIC ORCID; Martín-Requero, Ángeles CSIC ORCID artículo
closedAccessrestringido.pdf.jpgDec-2000Cloning and functional characterization of the 5´ regulatory region of the human mitochondrial glycerol-3-phosphate dehydrogenase gene. Lack of 3,5,3´-triiodothyronine responsiveness in adipose tissueUrcelay, Elena; Jareño, María A.; Menaya, Juan; Parrilla, Roberto L.; Sánchez Ayuso, Matilde CSIC ORCID ; Martín-Requero, Ángeles CSIC ORCID artículo
openAccessES2686909A1.pdf.jpg22-Oct-2018Compuestos inhibidores de CDC-7 y su uso para el tratamiento de patologías neurológicasMartinez Gil, Ana ; Pérez, Daniel I.; Gil, Carmen ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa; Martínez-González, Loreto CSIC ORCID CVN ; Pérez, Concepciónsolicitud de patente
openAccessES2686909B1.pdf.jpg22-Oct-2018Compuestos inhibidores de CDC-7 y su uso para el tratamiento de patologías neurológicasMartínez, Ana CSIC ORCID ; Pérez, Daniel I.; Gil, Carmen ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa; Martínez-González, Loreto CSIC ORCID CVN ; Pérez, Concepciónpatente
openAccessES2749743A1.pdf.jpg23-Mar-2020Derivados de purina inhibidores de CDC7 y su uso para el tratamiento de patologías neurológicasMartínez, Ana CSIC ORCID ; Gil, Carmen ; Martín-Requero, Ángeles CSIC ORCID ; Rojas-Prats, Elisa; Martínez-González, Loreto CSIC ORCID CVN solicitud de patente
openAccessijcep 2009, 2 (390-398).pdf.jpg1-Dec-2009Distinct regulation of cell cycle and survival in lymphocytes from patients with Alzheimer´s disease and amyotrophic lateral sclerosisBartolomé Robledo, Fernando CSIC ORCID CVN; Muñoz, Úrsula CSIC; Esteras, Noemí; Esteban, Jesús; Bermejo-Pareja, Félix; Martín-Requero, Ángeles CSIC ORCID artículo
openAccessEsteras_NBA_34_2013_1090-1100.pdf.jpgApr-2013Downregulation of ERK1/2 activity by CaMKII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer’s disease patientsEsteras, Noemí; Alquézar, Carolina CSIC ORCID; Bermejo-Pareja, Félix; Bialopiotrowicz, Emilia; Wojda, Urszula; Martín-Requero, Ángeles CSIC ORCID artículo