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Showing results 1 to 19 of 19
RightsPreviewIssue DateTitleAuthor(s)Type
openAccessACSChemNeurosci 2018.pdf.jpg9-Oct-2018A focused library of psychotropic analogs with neuroprotective and neuroregenerative potentialUliassi, Elisa; Peña-Altamira, Luis Emiliano; Morales, Aixa V. ; Massenzio, Francesca; Petralla, Sabrina; Rossi, Michele; Roberti, Marinella; Martínez-González, Loreto ; Martínez, Ana  ; Monti, B.; Bolognesi, Maria Lauraartículo
openAccessWO2018172587A1.pdf.jpg27-Sep-2018CDC-7-inhibitors compounds and use thereof for the treatment of neurological conditionsMartinez Gil, Ana ; Pérez, Daniel I.; Gil, Carmen  ; Martín-Requero, Ángeles  ; Rojas-Prats, Elisa; Martínez-González, Loreto ; Pérez, Concepciónsolicitud de patente
openAccessWO2020058558A1.pdf.jpg26-Mar-2020CDC7-Inhibiting purine derivatives and their use for the treatment of neurological conditionsMartínez, Ana  ; Gil, Carmen  ; Martín Requero, A.; Rojas-Prats, Elisa; Martínez-González, Loreto solicitud de patente
closedAccessaccesoRestringido.pdf.jpg2018Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitorsChierrito, Talita P. C.; Pedersoli-Mantoani, S.; Roca, Carlos; Sebastián-Pérez, Víctor; Martínez-González, Loreto ; Pérez, Daniel I.; Pérez, Concepción; Canales, A.; Cañada, F. Javier  ; Campillo, Nuria E.  ; Carvalho, Ivone; Martínez, Ana  artículo
openAccessES2686909A1.pdf.jpg22-Oct-2018Compuestos inhibidores de CDC-7 y su uso para el tratamiento de patologías neurológicasMartinez Gil, Ana ; Pérez, Daniel I.; Gil, Carmen  ; Martín-Requero, Ángeles  ; Rojas-Prats, Elisa; Martínez-González, Loreto ; Pérez, Concepciónsolicitud de patente
openAccessJEIMC_Sciú_2018.pdf.jpg1-Jan-2019Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3Sciú, María Lourdes; Sebastián-Pérez, Víctor; Martínez-González, Loreto ; Benitez, Rocio; Perez, Daniel I.; Pérez, Concepción; Campillo, Nuria E.  ; Martínez, Ana; Moyano, Elizabeth Lauraartículo
closedAccessaccesoRestringido.pdf.jpg2018Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function RegulatorsRoca, Carlos; Martínez-González, Loreto ; Daniel-Mozo, M.; Sastre, J. ; Infantes, L. ; Mansilla, A.; Chaves-Sanjuan, A.; Gonzalez-Rubio, Juana M; Gil, C ; Cañada, F. Javier  ; Martinez, A. ; Sánchez-Barrena, María José ; Campillo, Nuria E.  artículo
openAccessES2749743A1.pdf.jpg23-Mar-2020Derivados de purina inhibidores de CDC7 y su uso para el tratamiento de patologías neurológicasMartínez, Ana  ; Gil, Carmen  ; Martín-Requero, Ángeles  ; Rojas-Prats, Elisa; Martínez-González, Loreto solicitud de patente
openAccessmolecules-24-01307.pdf.jpg3-Apr-2019Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer’s DiseaseKohelová, Eliška; Peřinová, Rozálie; Maafi, Negar; Korábečný, Jan; Hulcová, Daniela; Maříková, Jana; Kučera, Tomáš; Martínez-González, Loreto ; Hrabinová, Martina; Vorčáková, Katarina; Nováková, Lucie; De Simone, Angela; Havelek, Radim; Cahlíková, Lucieartículo
openAccessNature Communications_Canal-Martín_2019.pdf.jpg26-Jun-2019Insights into real-time chemical processes in a calcium sensor protein-directed dynamic libraryCanal-Martín, Andrea; Sastre, Javier; Sánchez-Barrena, María José ; Canales, Ángeles ; Baldominos, Sara; Pascual, Naiara; Martínez-González, Loreto ; Molero, Dolores; Fernández-Valle, Encarnación; Sáez, Elena; Blanco-Gabella, Patricia; Gomez-Rubio, Elena; Martín-Santamaría, Sonsoles ; Sáiz, Almudena; Mansilla, A.; Cañada, F. Javier  ; Jiménez-Barbero, Jesús ; Martínez, Ana; Pérez-Fernández, Ruth  artículo
closedAccessaccesoRestringido.pdf.jpg2017Interference of the complex between NCS-1 & Ric8a with phenothiazines regulates synaptic function & is an approach for fragile X syndromeMansilla, Alicia ; Chaves Sanjuán, Antonio; Campillo, Nuria E.  ; Semelidou, O.; Martínez-González, Loreto ; Infantes, L. ; Gonzalez-Rubio, Juana M.; Gil, Carmen  ; Conde, Santiago ; Skoulakis, E.M.C.; Ferrús, Alberto ; Martínez, Ana  ; Sánchez-Barrena, María José artículo
openAccessScientific Reports_Martínez-González_2020.pdf.jpg10-Mar-2020Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatmentMartínez-González, Loreto ; Rodríguez-Cueto, Carmen; Cabezudo, Diego; Bartolomé Robledo, Fernando ; Andrés-Benito, Pol; Ferrer, Isidro; Gil, Carmen  ; Martín-Requero, Ángeles  ; Fernández-Ruiz, Javier; Martínez, Ana  ; De Lago, E.artículo
openAccessNew protein-protein .pdf.jpg20-Jul-2019New protein-protein interaction modulators for the therapeutic regulation of synapse dysfunction in neurodevelopmental disorders and neurodegenerationMansilla, A.; Chaves-Sanjuan, A.; Roca, Carlos; Canal-Martín, Andrea; Daniel-Mozo, M.; Martínez-González, Loreto ; Infantes, L. ; Ferrús, Alberto ; Martínez, A.; Pérez-Fernández, Ruth  ; Campillo, Nuria E.  ; Sánchez-Barrena, María José comunicación de congreso
embargoedAccess14-Jul-2020Novel Curcumin-Diethyl Fumarate Hybrid as a dualistic GSK-3β inhibitor/Nrf2 inducer for the treatment of Parkinson’s diseaseDi Martino, Rita Maria Concetta; Pruccoli, Letizia; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Martínez, Ana  ; Pérez, Concepción; Martínez-González, Loreto ; Paglione, Maria; Di Schiavi, Elia; Seghetti, Francesca; Tarozzi, Andrea; Belluti, Federicaartículo
openAccessMolecular Neurobiology_Posa et al_2018 .pdf.jpg20-Jul-2018Recapitulation of pathological TDP-43 features in immortalized lymphocytes from sporadic ALS patientsPosa, Diana; Martínez-González, Loreto ; Bartolomé Robledo, Fernando ; Siranjeevi, Nagaraj; Porras, Gracia  ; Martínez, Ana  ; Martín-Requero, Ángeles  artículo
embargoedAccess15-Jan-2021Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosisRojas-Prats, Elisa; Martínez-González, Loreto ; Gonzalo-Consuegra, Claudia; Liachko, Nicole F.; Pérez, Concepción; Ramírez, David; Kraemer, Brian C.; Martín-Requero, Ángeles  ; Pérez, Daniel I.; Gil, Carmen  ; De Lago, E.; Martínez, Ana  artículo
closedAccessaccesoRestringido.pdf.jpg2018Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation InhibitorsGandini, A.; Bartolini, M.; Tedesco, D.; Martínez-González, Loreto ; Roca, Carlos; Campillo, Nuria E.  ; Zaldívar-Díez, Josefa; Pérez, Concepción; Zuccheri, G.; Miti, A.; Feoli, A.; Castellano, S.; Petralla, S.; Monti, B.; Rossi, M.; Moda, F.; Legname, G.; Martínez, Ana; Bolognesi, Maria Lauraartículo
openAccessCongreso Atenas p.121.pdf.jpgSep-2019TDP-43 modulation by CDC7 inhibitors as a therapeutic strategy for amyotrophic lateral sclerosisRojas-Prats, Elisa; Martínez-González, Loreto ; Liachko, Nicole F.; Kraemer, Brian C.; Gil, Carmen  ; Martín-Requero, Ángeles  ; Martínez, Ana  comunicación de congreso
embargoedAccessJournal of Neurochemistry_Vaca et al  postprint 2020.pdf.jpg17-Jul-2020Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and Amyotrophic Lateral Sclerosis (ALS)Vaca, Gabriela; Martínez-González, Loreto ; Fernandez, Ana; Rojas-Prats, Elisa; Porras, Gracia  ; Cuevas, Eva P. ; Gil, Carmen  ; Martínez, Ana  ; Martín-Requero, Ángeles  artículo