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closedAccessaccesoRestringido.pdf.jpg16-Jan-2017A biophysical toolkit for molecular interactionsSantiveri, Clara M.; López-Méndez, Blanca; Huecas, Sonia CSIC ORCID ; Alfonso, Carlos CSIC ORCID ; Luque-Ortega, Juan Román CSIC ORCID ; Campos-Olivas, Ramónartículo
openAccessBodipy_Torre.pdf.jpgApr-2014A BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drugGarcía de la Torre, Beatriz; Hornillos, Valentín CSIC ORCID; Luque-Ortega, Juan Román CSIC ORCID ; Abengozar, M. A. CSIC; Amat-Guerri, Francisco CSIC; Ulises Acuña, A.; Rivas, Luis CSIC ORCID ; Andreu, Davidartículo
openAccesspgen_Alfonso, C._2014.pdf.jpg23-Oct-2014A complex genetic switch involving overlapping divergent promoters and DNA looping regulates expression of conjugation genes of a gram-positive plasmidRamachandran, Gayetri CSIC; Singh, Praveen Kumar CSIC ORCID; Luque-Ortega, Juan Román CSIC ORCID ; Yuste, Luis; Alfonso, Carlos CSIC ORCID ; Rojo, Fernando ; Wu, Ling Juan; Meijer, Wilfried J. J. CSIC ORCIDartículo
embargoedAccessCAN-RESEARCH_TEMPS_2021.pdf.jpg20-Aug-2021A novel mode of inhibiting SRC improves drug efficacy and tolerabilityTemps, Caroline; Lietha, Daniel CSIC ORCID ; Webb, Emily R.; Li, Xue-Feng; Dawson, John C.; Muir, Morwenna; Macleod, Kenneth G.; Valero, Teresa; Munro, Alison F.; Contreras-Montoya, Rafael; Luque-Ortega, Juan Román CSIC ORCID ; Fraser, Craig; Beetham, Henry; Schoenherr, Christina; Lopalco, Maria; Arends, Mark J.; Frame, Margaret C.; Qian, Bin-Zhi; Brunton, Valerie G.; Carragher, Neil O.; Unciti-Broceta, Asierartículo
closedAccess2009Amphibian antimicrobial peptides and Protozoa: Lessons from parasitesRivas, Luis CSIC ORCID ; Luque-Ortega, Juan Román CSIC ORCID ; Andreu, Davidartículo
openAccesspgen.ramachandran_2017.pdf.jpg16-Feb-2017Discovery of a new family of relaxases in Firmicutes bacteriaRamachandran, Gayetri CSIC; Miguel-Arribas, Andrés; Abia, David CSIC ORCID ; Singh, Praveen Kumar CSIC ORCID; Crespo, Isidro; Gago-Córdoba, César; Hao, Jian-An; Luque-Ortega, Juan Román CSIC ORCID ; Alfonso, Carlos CSIC ORCID ; Wu, Ling J.; Boer, Roeland CSIC ORCID; Meijer, Wilfried J. J. CSIC ORCIDartículo
openAccessJBC_Esperante_2021.pdf.jpgSep-2021Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregationEsperante, Sebastian; Varejão, Nathalia; Pinheiro, Francisca; Sant’Anna, Ricardo; Luque-Ortega, Juan Román CSIC ORCID ; Alfonso, Carlos CSIC ORCID ; Sora, Valentina; Papaleo, Elena; Rivas, Germán CSIC ORCID ; Reverter, David; Ventura, Salvadorartículo
openAccess2360548_A1.pdf.jpg7-Jun-2011Formulaciones de lipoaminoácidos catiónicos con menor poder hemolítico basadas en la formación de pares cataniónicosFernández-Reyes, María CSIC ORCID; Infante Martínez-Pardo, María Rosa; Luque-Ortega, Juan Román CSIC ORCID ; Pérez, Lourdes CSIC ORCID; Morán Bádenas, Carmen; Pons Pons, Ramon; Rivas, Luis CSIC ORCID ; Pinazo Gassol, Aurora; Lozano Valdés, Neus CSIC ORCIDsolicitud de patente
openAccessWO2011058210A1.pdf.jpg19-May-2011Formulations of cationic lipoamino acids with lower haemolytic power based on the formation of catanionic pairsPons Pons, Ramon; Pinazo Gassol, Aurora; Lozano Valdés, Neus CSIC ORCID; Rivas, Luis CSIC ORCID ; Fernández-Reyes, María CSIC ORCID; Luque-Ortega, Juan Román CSIC ORCID ; Pérez, Lourdes CSIC ORCID; Infante Martínez-Pardo, María Rosa; Morán Bádenas, Carmensolicitud de patente
closedAccessrestringido.pdf.jpg1-Jun-2008Human antimicrobial peptide histatin 5 is a cell-penetrating peptide targeting mitochondrial ATP synthesis in LeishmaniaLuque-Ortega, Juan Román CSIC ORCID ; van´t Hof, Wim; Veerman, Enno C.I.; Saugar, José María; Rivas, Luis CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2020Human importin α3 and its N-terminal truncated form, without the importin-β-binding domain, are oligomeric species with a low conformational stability in solutionDíaz-García, Clara; Hornos, Felipe; Giudici, A. Marcela; Cámara-Artigas, Ana; Luque-Ortega, Juan Román CSIC ORCID ; Arbe, Arantxa CSIC ORCID; Rizzuti, Bruno; Alfonso, Carlos CSIC ORCID ; Forwood, Jade K.; Iovanna, Juan L.; Gómez, Javier; Prieto, Manuel; Coutinho, Ana; Neira, José L.artículo
openAccessApr-2001In vivo monitoring of intracellular ATP levels in Leishmania donovani promastigotes as a rapid method to screen drugs targeting bioenergetic metabolismLuque-Ortega, Juan Román CSIC ORCID ; Rivero-Lezcano, Octavio Miguel; Croft, S.L.; Rivas, Luis CSIC ORCID artículo
openAccessNucleic Acids Research_Crespo_2020.pdf.jpg13-Jul-2020Inactivation of the dimeric RappLS20 anti-repressor of the conjugation operon is mediated by peptide-induced tetramerizationCrespo, Isidro; Bernardo, Nerea; Miguel-Arribas, Andrés; Singh, Praveen Kumar CSIC ORCID; Luque-Ortega, Juan Román CSIC ORCID ; Alfonso, Carlos CSIC ORCID ; Malfois, Marc; Meijer, Wilfried J. J. CSIC ORCID; Boer, Roeland CSIC ORCIDartículo
openAccessLUQUE-ORTEGA-JUAN-ROMAN-TESEO.pdf.jpg2-Mar-2011El metabolismo energético de Leishmania como diana de nuevas moléculas leishmanicidasLuque-Ortega, Juan Román CSIC ORCID tesis doctoral
openAccessApr-2007Miltefosine (hexadecylphosphocholine) inhibits cytochrome c oxidase in Leishmania donovani promastigotesLuque-Ortega, Juan Román CSIC ORCID ; Rivas, Luis CSIC ORCID artículo
openAccessMultiple LayeredControloftheConjugation.pdf.jpg18-Mar-2021Multiple Layered Control of the Conjugation Process of the Bacillus subtilis Plasmid pLS20Meijer, Wilfried J. J; Boer, D. Roeland; Ares, Saúl; Alfonso, Carlos CSIC ORCID ; Rojo, Fernando ; Luque-Ortega, Juan Román CSIC ORCID ; Wu, Ling Juanartículo
Luque-Ortega JMC2010_postprint.pdf.jpg2010New Benzophenone-derived bisphosphonium salts as leishmanicidal leads targeting mitochondria through inhibition of respiratory complex IILuque-Ortega, Juan Román CSIC ORCID ; Reuther, Peter; Rivas, Luis CSIC ORCID ; Dardonville, Christophe CSIC ORCID artículo
openAccessMeijerWJJ_NovelRegulatoryMechanism.pdf.jpg31-Oct-2018Novel regulatory mechanism of establishment genes of conjugative plasmidsVal-Calvo, Jorge; Luque-Ortega, Juan Román CSIC ORCID ; Crespo, Isidro; Miguel-Arribas, Andrés; Abia, David CSIC ORCID ; Sánchez-Hevia, Dione L.; Serrano, Ester; Gago-Córdoba, César; Ares, Saúl; Alfonso, Carlos CSIC ORCID ; Rojo, Fernando ; Wu, Ling Juan; Boer, Roeland CSIC ORCID; Meijer, Wilfried J. J. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg15-Aug-2017Recombinant vs native Anisakis haemoglobin (Ani s 13): Its appraisal as a new gold standard for the diagnosis of allergyGonzález-Fernández, Juan; Rivas, Luis CSIC ORCID ; Luque-Ortega, Juan Román CSIC ORCID ; Núñez-Ramírez, Rafael CSIC ; Campioli, Pamela; Gárate, Teresa; Perteguer, M. J.; Daschner, Alvaro; Cuéllar, Carmenartículo
closedAccessaccesoRestringido.pdf.jpg2007Synthesis and biological evaluation of fluorescent leishmanicidal analogues of hexadecylphosphocholine (Miltefosine) as probes of antiparasite mechanismsSaugar, José María; Delgado, Javier; Hornillos, Valentín CSIC ORCID; Luque-Ortega, Juan Román CSIC ORCID ; Amat-Guerri, Francisco CSIC; Acuña, A. Ulises CSIC; Rivas, Luis CSIC ORCID artículo