Rights | Preview | Issue Date | Title | Author(s) | Type |
openAccess |  | 2018 | Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity | Bueno, Oskía; Tobajas, Gloria; Quesada, Ernesto; Estévez-Gallego, Juan ; Noppen, Sam; Camarasa Rius, María José ; Díaz, José Fernando ; Liekens, Sandra; Priego, Eva María ; Peréz-Pérez, María-Jesús | artículo |
|  | 20-Mar-2019 | Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands | Balaguer, Francisco de Asís; Mühlethaler, Tobias; Estévez-Gallego, Juan ; Calvo, Enrique; Giménez-Abián, Juan F. ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. ; Prota, Andrea E.; Díaz, José Fernando | artículo |
closedAccess |  | Jun-2019 | Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the aT5 loop | Bueno, Oskia; Gargantilla, Marta; Estévez-Gallego, Juan ; Martins, Solange; Díaz, José Fernando ; Camarasa Rius, María José ; Liekens, Sandra; Peréz-Pérez, María-Jesús ; Priego, Eva María  | artículo |
openAccess |  | 2018 | High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design | Bueno, Oskía; Estévez-Gallego, Juan ; Martins, S.; Prota, Andrea E.; Gago, Federico ; Gómez-SanJuan, Asier; Camarasa Rius, María José ; Barasoain, Isabel ; Steinmetz, Michel O.; Díaz, Fernando J.; Peréz-Pérez, María-Jesús ; Liekens, Sandra; Priego, Eva María  | artículo |
openAccess |  | 3-Jun-2017 | Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions. | Tang, Yong; Rodríguez-Salarichs, Javier; Estévez-Gallego, Juan ; Balaguer, Francisco de Asís; Redondo-Horcajo, Mariano ; Lucena-Agell, Daniel ; Barasoain, Isabel ; Díaz, José Fernando ; Fang, Wei-shuo S. | artículo |
openAccess |  | 2020 | On the Importance of the Thiazole Nitrogen in Epothilones: Semisynthesis and Microtubule-Binding Affinity of Deaza-Epothilone C | Edenharter, Adriana; Ryckewaert, Lucie; Cintulová, Daniela; Estévez-Gallego, Juan ; Díaz, José Fernando ; Altmann, Karl-Heinz | artículo |
openAccess |  | 10-Mar-2020 | Structural model for differential cap maturation at growing microtubule ends | Estévez-Gallego, Juan ; Josa-Prado, Fernando; Ku, Siou; Martínez Buey, Rubén ; Balaguer, Francisco de Asís; Prota, Andrea E.; Lucena-Agell, Daniel ; Kamma-Lorger, C.S.; Yagi, Toshiki; Iwamoto, Hiroyuki; Duchesne, Laurence; Barasoain, Isabel ; Steinmetz, Michel O.; Chrétien, Denis; Kamimura, Shinji; Díaz, José Fernando ; Oliva, María A. | artículo |
closedAccess |  | 2016 | Targeting the colchicine site in tubulin through cyclohexanedione derivatives | Canela, María-Dolores ; Bueno, O.; Noppen, Sam; Sáez-Calvo, Gonzalo; Estévez-Gallego, Juan ; Díaz, José Fernando ; Camarasa Rius, María José ; Liekens, Sandra; Peréz-Pérez, María-Jesús ; Priego, Eva María  | artículo |
openAccess |  | 12-Oct-2017 | Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sites | Field, Jessica J.; Pera, Benet ; Estévez-Gallego, Juan ; Rodríguez-Salarichs, Javier; Sáez-Calvo, Gonzalo; Andreu, José Manuel ; Díaz, José Fernando | artículo |