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RightsPreviewIssue DateTitleAuthor(s)Type
openAccessaccesoRestringido.pdf.jpg2018Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activityBueno, Oskía; Tobajas, Gloria; Quesada, Ernesto; Estévez-Gallego, Juan CSIC ORCID ; Noppen, Sam; Camarasa Rius, María José CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Liekens, Sandra; Priego, Eva María CSIC ORCID; Peréz-Pérez, María-Jesús CSIC ORCID artículo
openAccessijms-20-01392.pdf.jpg20-Mar-2019Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site LigandsBalaguer, Francisco de Asís; Mühlethaler, Tobias; Estévez-Gallego, Juan CSIC ORCID ; Calvo, Enrique; Giménez-Abián, Juan F. CSIC ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. CSIC ORCID ; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
closedAccessEJMC_Diphenyl_ether_derivatives_2019.pdf.jpgJun-2019Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the aT5 loopBueno, Oskia; Gargantilla, Marta; Estévez-Gallego, Juan CSIC ORCID ; Martins, Solange; Díaz, José Fernando CSIC ORCID ; Camarasa Rius, María José CSIC ORCID; Liekens, Sandra; Peréz-Pérez, María-Jesús CSIC ORCID ; Priego, Eva María CSIC ORCIDartículo
openAccessScientific reports(2018)4242.pdf.jpg2018High-affinity ligands of the colchicine domain in tubulin based on a structure-guided designBueno, Oskía; Estévez-Gallego, Juan CSIC ORCID ; Martins, S.; Prota, Andrea E.; Gago, Federico CSIC ORCID; Gómez-SanJuan, Asier; Camarasa Rius, María José CSIC ORCID; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Díaz, Fernando J.; Peréz-Pérez, María-Jesús CSIC ORCID ; Liekens, Sandra; Priego, Eva María CSIC ORCIDartículo
openAccess2017 Tang et al.pdf.jpg3-Jun-2017Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.Tang, Yong; Rodríguez-Salarichs, Javier; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.artículo
openAccessImportance_Edenharter_Art2020.pdf.jpg2020On the Importance of the Thiazole Nitrogen in Epothilones: Semisynthesis and Microtubule-Binding Affinity of Deaza-Epothilone CEdenharter, Adriana; Ryckewaert, Lucie; Cintulová, Daniela; Estévez-Gallego, Juan CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinzartículo
openAccesselife-Estévez-Gallego-2020.pdf.jpg10-Mar-2020Structural model for differential cap maturation at growing microtubule endsEstévez-Gallego, Juan CSIC ORCID ; Josa-Prado, Fernando; Ku, Siou; Martínez Buey, Rubén CSIC ORCID CVN; Balaguer, Francisco de Asís; Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Kamma-Lorger, C.S.; Yagi, Toshiki; Iwamoto, Hiroyuki; Duchesne, Laurence; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Chrétien, Denis; Kamimura, Shinji; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2016Targeting the colchicine site in tubulin through cyclohexanedione derivativesCanela, María-Dolores CSIC; Bueno, O.; Noppen, Sam; Sáez-Calvo, Gonzalo; Estévez-Gallego, Juan CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Camarasa Rius, María José CSIC ORCID; Liekens, Sandra; Peréz-Pérez, María-Jesús CSIC ORCID ; Priego, Eva María CSIC ORCIDartículo
openAccessJNP_2017 Field et al.pdf.jpg12-Oct-2017Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sitesField, Jessica J.; Pera, Benet CSIC; Estévez-Gallego, Juan CSIC ORCID ; Rodríguez-Salarichs, Javier; Sáez-Calvo, Gonzalo; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID artículo