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openAccessmBio-2017-Wagstaff-.pdf.jpg2-May-2017A polymerization-associated structural switch in FtsZ that enables treadmilling of model filamentsWagstaff, James M.; Tsim, Matthew; Oliva, María A. CSIC ORCID ; García-Sánchez, Alba; Kureisaite-Cizien, Danguole; Andreu, José Manuel CSIC ORCID ; Löwe, Janartículo
openAccessmBio-2017-Wagstaff-.pdf.jpg2019A Polymerization-Associated Structural Switch in FtsZ That Enables Treadmilling of Model FilamentsWagstaff, James M.; Tsim, Matthew; Oliva, María A. CSIC ORCID ; García-Sanchez, Alba; Kureisaite-Ciziene, Danguole; Andreu, José Manuel CSIC ORCID ; Löwe, Janartículo
openAccessacsomega_oliva_2023.pdf.jpg13-Jan-2023Alternative approaches to understand microtubule cap morphology and functionOliva, María A. CSIC ORCID ; Gago, Federico CSIC ORCID; Kamimura, Shinji; Díaz, José Fernando CSIC ORCID artículo
openAccessJ. Biol. Chem.-2003-Oliva-33562-70.pdf.jpg29-Aug-2003Assembly of archaeal cell division protein FtsZ and a GTPase-inactive mutant into double-stranded filamentsOliva, María A. CSIC ORCID ; Huecas, Sonia CSIC ORCID ; Palacios, Juan Manuel; Martín-Benito, Jaime CSIC ORCID; Valpuesta, José M. CSIC ORCID ; Andreu, José Manuel CSIC ORCID artículo
openAccessJ. Biol. Chem.-2011-Martin-Galiano-19789-803.pdf.jpg3-Jun-2011Bacterial Tubulin Distinct Loop Sequences and Primitive Assembly Properties Support its Origin from a Eukaryotic Tubulin AncestorMartín-Galiano, Antonio J. CSIC ORCID; Oliva, María A. CSIC ORCID ; Sanz, Laura CSIC ORCID; Anamitra, Bhattacharyya; Serna, Marina CSIC ORCID; Yébenes, Hugo CSIC ORCID; Valpuesta, José M. CSIC ORCID ; Andreu, José Manuel CSIC ORCID artículo
openAccesspostprint-Bacterial tubulin_MCB 2R.pdf.jpg2013Chapter 17-Purification and assembly of bacterial tubulin BtubA/B and constructs bearing eukaryotic tubulin sequencesAndreu, José Manuel CSIC ORCID ; Oliva, María A. CSIC ORCID capítulo de libro
openAccessJan-2023Chemical modulation of microtubule structure as a tool to target different diseasesEstévez-Gallego, Juan CSIC ORCID ; Álvarez-Bernad, Beatriz CSIC; Lucena-Agell, Daniel CSIC ORCID ; Bonato, Francesca CSIC ORCID; Giménez-Abián, Juan F. CSIC ; Blanco, Óscar; París, Rebeca; Fuertes, L.; Martínez, J. C.; Kamimura, Shinji; Gago, Federico CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID comunicación de congreso
openAccessALBA Synchrotron_Oliva_2022.pdf.jpgSep-2022Chemical modulation of microtubule structure in neurodegenerative diseasesOliva, María A. CSIC ORCID comunicación de congreso
openAccessStructure_Estévez-Gallego_2022.pdf.jpg5-Jan-2023Chemical modulation of microtubule structure through the laulimalide/peloruside siteEstévez-Gallego, Juan CSIC ORCID ; Álvarez-Bernad, Beatriz CSIC; Benet, Pera; Wullschleger, Christoph; Raes, Olivier; Menche, Dirk; Martínez, Juan Carlos; Lucena-Agell, Daniel CSIC ORCID ; Prota, Andrea E.; Bonato, Francesca CSIC ORCID; Bargsten, Katja; Cornelus, Jelle; Giménez-Abián, Juan F. CSIC ; Northcote, Peter; Steinmetz, Michel O.; Kamimura, Shinji; Altmann, Karl-Heinz; Paterson, Ian; Gago, Federico CSIC ORCID; Van der Eycken, Johan; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID artículo
openAccessijms-20-01392.pdf.jpg20-Mar-2019Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site LigandsBalaguer, Francisco de Asís CSIC ORCID; Mühlethaler, Tobias; Estévez-Gallego, Juan CSIC ORCID ; Calvo, Enrique; Giménez-Abián, Juan F. CSIC ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. CSIC ORCID ; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
openAccessPREPRINTCrystal_structures_of_taxane-tubulin_complexes_Imp.pdf.jpg2021Crystal structures of taxane-tubulin complexes: Implications for the mechanism of microtubule stabilization by TaxolProta, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Ma, Yuntao; Estévez-Gallego, Juan CSIC ORCID ; Roca, Carlos CSIC ORCID; Josa-Prado, Fernando CSIC ORCID; Goossens, Kenneth; Giménez-Abián, Juan F. CSIC ; Li, Shuo; Canales, Ángeles CSIC ORCID; Bargsten, Katja; Andreu, José Manuel CSIC ORCID ; Altmann, Karl-Heinz; Olieric, Natacha; Kamimura, Shinji; Mühlethaler, Tobias; Oliva, María A. CSIC ORCID ; Steinmetz, Michel O.; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID preprint
openAccessijms-23-03448-v2.pdf.jpg22-Mar-2022Effect of Clinically Used Microtubule Targeting Drugs on Viral Infection and Transport FunctionOliva, María A. CSIC ORCID ; Tosat-Bitrian, Carlota CSIC ORCID ; Barrado-Gil, Lucía CSIC ORCID; Bonato, Francesca CSIC ORCID; Galindo Barreales, Inmaculada; Garaigorta, Urtzi ; Álvarez-Bernad, Beatriz CSIC; París-Ogáyar, Rebeca CSIC ORCID; Lucena-Agell, Daniel CSIC ORCID ; Giménez-Abián, Juan F. CSIC ; García-Dorival, Isabel; Urquiza, Jesús; Gastaminza, Pablo CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Palomo, Valle CSIC ORCID ; Alonso Martí, Covadongaartículo
openAccesspostprint_EMBO_25507_1_merged_1271683818.pdf.jpg16-Jun-2010Features critical for membrane binding revealedby DivIVA crystal structureOliva, María A. CSIC ORCID ; Halbedel, Sven; Dutow, Pavel; Leonard, Thomas A.; Veprintsev, Dmitry B.; Hamoen, L. W.; Löwe, Janartículo
closedAccessaccesoRestringido.pdf.jpg2005Folding, stability and polymerization properties of FtsZ chimeras with inserted tubulin loops involved in the interaction with the cytosolic chaperonin CCT and in microtubule formationBertrand, Sara; Barthelemy, Isabel; Oliva, María A. CSIC ORCID ; Carrascosa, José L. CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Valpuesta, José M. CSIC ORCID artículo
openAccessPNAS_Matthew_2020.pdf.jpg2-Mar-2021Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological siteMatthew, S.; Chen, Qi-Yin; Ratnayake, R.; Fermaintt, Charles S.; Lucena-Agell, Daniel CSIC ORCID ; Bonato, Francesca CSIC ORCID; Prota, Andrea E.; Lim, Seok Ting; Wang, Xiaomeng; Díaz, José Fernando CSIC ORCID ; Risinger, April L.; Paul, Valerie J.; Oliva, María A. CSIC ORCID ; Luesch, H.artículo
openAccessBioorganic Chemistry_Nemati_2021.pdf.jpg30-Jun-2021Identification of novel anti-cancer agents by the synthesis and cellular screening of a noscapine-based libraryNemati, Faezeh; Bischoff-Kont, Iris; Salehi, Peyman; Nejad-Ebrahimi, Samad; Mohebbi, Maryam; Bararjanian, Morteza; Hadian, Nasim; Hassanpour, Zahra; Jung, Yvonne; Schaerlaekens, Sofie; Lucena-Agell, Daniel CSIC ORCID ; Oliva, María A. CSIC ORCID ; Fürst, Robert; Nasiri, Hamid R.artículo
openAccessCancer Cell International_Keenan_2020.pdf.jpg2020N‑alkylisatin‑based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicityKeenan, Bryce; Finol-Urdaneta, Rocío; Hope, Ashleigh; Bremner, John B.; Kavallaris, Maria; Lucena-Agell, Daniel CSIC ORCID ; Oliva, María A. CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Vine, Kara L.artículo
openAccessII Jornadas Salud Global_Lucena Agell_Póster_ Valencia_ 2022.pdf.jpgOct-2022Pharmacological modulation of the interaction between tubulin and a SARS-CoV-2 proteinFuertes-Monge, Laura; Schaerlaekens, Sofie; Lucena-Agell, Daniel CSIC ORCID ; García-Dorival, Isabel; Cuesta-Geijo, Miguel Ángel CSIC ORCID; Barrado-Gil, Lucía CSIC ORCID; Galindo, Inmaculada; Alonso, Covadonga; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID póster de congreso
openAccessOlivaMATesis2005b.pdf.jpg17-Jun-2005Plegamiento y ensamblaje de la proteina de división celular FtsZ de Methanococcus jannaschii.Oliva, María A. CSIC ORCID tesis doctoral
openAccessjournal of medicinal chemistry_lucena-agell_2024.pdf.jpg31-Jan-2024PM534, an optimized target-protein interaction strategy through the colchicine site of tubulinLucena-Agell, Daniel CSIC ORCID ; Guillén, María José; Matesanz, Ruth CSIC ; Álvarez-Bernad, Beatriz CSIC; Hortigüela, Rafael CSIC ORCID; Avilés, Pablo; Martínez-Díez, Marta; Santamaría, Gema; Contreras, Julia CSIC; Plaza-Menacho, Iván; Giménez-Abián, Juan F. CSIC ; Oliva, María A. CSIC ORCID ; Cuevas, Carmen; Díaz, José Fernando CSIC ORCID artículo