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openAccessmBio-2017-Wagstaff-.pdf.jpg2-May-2017A polymerization-associated structural switch in FtsZ that enables treadmilling of model filamentsWagstaff, James M.; Tsim, Matthew; Oliva, María A. CSIC ORCID ; García-Sanchez, Alba; Kureisaite-Cizien, Danguole; Andreu, José Manuel CSIC ORCID ; Löwe, Janartículo
openAccessJ. Biol. Chem.-2003-Oliva-33562-70.pdf.jpg29-Aug-2003Assembly of archaeal cell division protein FtsZ and a GTPase-inactive mutant into double-stranded filamentsOliva, María A. CSIC ORCID ; Huecas, Sonia CSIC ORCID ; Palacios, Juan Manuel; Martín-Benito, Jaime; Valpuesta, José M. CSIC ORCID ; Andreu, José Manuel CSIC ORCID artículo
openAccessJ. Biol. Chem.-2011-Martin-Galiano-19789-803.pdf.jpg3-Jun-2011Bacterial Tubulin Distinct Loop Sequences and Primitive Assembly Properties Support its Origin from a Eukaryotic Tubulin AncestorMartín-Galiano, Antonio J.; Oliva, María A. CSIC ORCID ; Sanz, Laura; Anamitra, Bhattacharyya; Serna, Marina; Yébenes, Hugo; Valpuesta, José M. CSIC ORCID ; Andreu, José Manuel CSIC ORCID artículo
openAccessijms-20-01392.pdf.jpg20-Mar-2019Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site LigandsBalaguer, Francisco de Asís; Mühlethaler, Tobias; Estévez-Gallego, Juan CSIC ORCID ; Calvo, Enrique; Giménez-Abián, Juan F. CSIC ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. CSIC ORCID ; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2005Folding, stability and polymerization properties of FtsZ chimeras with inserted tubulin loops involved in the interaction with the cytosolic chaperonin CCT and in microtubule formationBertrand, Sara; Barthelemy, Isabel; Oliva, María A. CSIC ORCID ; Carrascosa, José L.; Andreu, José Manuel CSIC ORCID ; Valpuesta, José M. CSIC ORCID artículo
openAccessPNAS_Matthew_2020.pdf.jpg2-Mar-2021Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological siteMatthew, S.; Chen, Qi-Yin; Ratnayake, R.; Fermaintt, Charles S.; Lucena-Agell, Daniel CSIC ORCID ; Bonato, Francesca; Prota, Andrea E.; Lim, Seok Ting; Wang, Xiaomeng; Díaz, José Fernando CSIC ORCID ; Risinger, April L.; Paul, Valerie J.; Oliva, María A. CSIC ORCID ; Luesch, H.artículo
embargoedAccessBioorganic Chemistry_Nemati_2021.pdf.jpg30-Jun-2021Identification of novel anti-cancer agents by the synthesis and cellular screening of a noscapine-based libraryNemati, Faezeh; Bischoff-Kont, Iris; Salehi, Peyman; Nejad-Ebrahimi, Samad; Mohebbi, Maryam; Bararjanian, Morteza; Hadian, Nasim; Hassanpour, Zahra; Jung, Yvonne; Schaerlaekens, Sofie; Lucena-Agell, Daniel CSIC ORCID ; Oliva, María A. CSIC ORCID ; Fürst, Robert; Nasiri, Hamid R.artículo
openAccessCancer Cell International_Keenan_2020.pdf.jpg2020N‑alkylisatin‑based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicityKeenan, Bryce; Finol-Urdaneta, Rocío; Hope, Ashleigh; Bremner, John B.; Kavallaris, Maria; Lucena-Agell, Daniel CSIC ORCID ; Oliva, María A. CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Vine, Kara L.artículo
openAccessOlivaMATesis2005b.pdf.jpg17-Jun-2005Plegamiento y ensamblaje de la proteina de división celular FtsZ de Methanococcus jannaschii.Oliva, María A. CSIC ORCID tesis doctoral
openAccessJ. Biol. Chem.-2002-Andreu-43262-70.pdf.jpg8-Nov-2002Reversible unfolding of FtsZ cell division proteins from archaea and bacteria. Comparison with eukaryotic tubulin folding and assemblyAndreu, José Manuel CSIC ORCID ; Oliva, María A. CSIC ORCID ; Monasterio, Octavioartículo
openAccessSegrosome Complex Formation during DNA Trafficking.pdf.jpg9-Sep-2016Segrosome Complex Formation during DNA Trafficking in Bacterial Cell DivisionOliva, María A. CSIC ORCID artículo
openAccess2017BIOPHYSJ.pdf.jpg17-Oct-2017Self-organization of FtsZ polymers in solution reveals spacer role of the disordered C-terminal tailHuecas, Sonia CSIC ORCID ; Ramírez-Aportela, Erney; Vergonos, A.; Núñez-Ramírez, Rafael CSIC ; Llorca, Óscar; Díaz, José Fernando CSIC ORCID ; Juan-Rodríguez, David; Oliva, María A. CSIC ORCID ; Castellen, Patricia; Andreu, José Manuel CSIC ORCID artículo
openAccessacs.jmedchem_Oliva_2020.pdf.jpg13-Jul-2020Structural basis of noscapine activation for tubulin bindingOliva, María A. CSIC ORCID ; Prota, Andrea E.; Rodríguez-Salarichs, Javier; Wenxin, Gu; Bennani, Y. L.; Jiménez-Barbero, Jesús CSIC ORCID; Bargsten, Katja; Canales, Ángeles CSIC ORCID; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID artículo
openAccesselife-Estévez-Gallego-2020.pdf.jpg10-Mar-2020Structural model for differential cap maturation at growing microtubule endsEstévez-Gallego, Juan CSIC ORCID ; Josa-Prado, Fernando; Ku, Siou; Martínez Buey, Rubén CSIC ORCID CVN; Balaguer, Francisco de Asís; Prota, Andrea E.; Lucena-Agell, Daniel CSIC ORCID ; Kamma-Lorger, C.S.; Yagi, Toshiki; Iwamoto, Hiroyuki; Duchesne, Laurence; Barasoain, Isabel CSIC ; Steinmetz, Michel O.; Chrétien, Denis; Kamimura, Shinji; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2005Structure of bacterial tubulin BtubA/B: Evidence for horizontal gene transferSchlieper, Daniel; Oliva, María A. CSIC ORCID ; Andreu, José Manuel CSIC ORCID ; Löwe, Janartículo
openAccessChem. Science_2016.pdf.jpg21-Oct-2016The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitorsArtola, Marta; Ruiz-Avila, Laura B.; Ramírez-Aportela, Erney; Araújo-Bazán, Lidia CSIC ORCID ; Oliva, María A. CSIC ORCID ; Martín-Galiano, Antonio J.; Chacón, Pablo CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Huecas, Sonia CSIC ORCID artículo
openAccessThe TubR-centromere complex adopts....pdf.jpg20-Jun-2018The TubR-centromere complex adopts a double-ring segrosome structure in Type III partition systemsMartín-García, Bárbara; Martín-González, Alejandro; Carrasco, Carolina; Ruíz-Quero, Rubén; Díaz-Orejas, Ramón CSIC; Aicart-Ramos, Clara; Moreno-Herrero, Fernando; Oliva, María A. CSIC ORCID ; Hernández-Arriaga, A.M. CSIC ORCID artículo
openAccesssrep2017.pdf.jpg23-Feb-2017TubZ filament assembly dynamics requires the flexible C-terminal tailFuentes-Perez, M. E.; Núñez-Ramírez, Rafael CSIC ; Martín-González, Alejandro; Juan-Rodríguez, David; Llorca, Óscar; Moreno-Herrero, Fernando; Oliva, María A. CSIC ORCID artículo
openAccessantagonistic_microtubule_drugs_kill_cancer_cells.pdf.jpg6-Aug-2020Two antagonistic microtubule targeting drugs act synergistically to kill cancer cellsPeronne, Lauralie; Denarier, Eric; Rai, Ankit; Prudent, Renaud; Vernet, Audrey; Suzanne, Peggy; Ramirez-Rios, Sacnicté; Michallet, Sophie; Guidetti, Mélanie; Vollaire, Julien; Lucena-Agell, Daniel CSIC ORCID ; Ribba, Anne-Sophie; Josserand, Véronique; Coll, Jean-Luc; Dallemagne, Patrick; Díaz, J. Fernando; Oliva, María A. CSIC ORCID ; Sadoul, Karin; Akhmanova, Anna; Andrieux, Annie; Lafanechère, Laurenceartículo