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Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 5-may-2011 | 1,8-Naphthyridine-devired compounds and the use thereof in the treatment of neurodegenerative diseases | Ríos Salgado, Cristóbal; Romero Martínez, Alejandro; Egea, Javier; León, Rafael CSIC ORCID ; Villarroya Sánchez, Mercedes; García López, Manuela; García García, Antonio; Marco-Contelles, José CSIC ORCID; Soriano, Elena CSIC; Samadi, Abdelouahid CSIC ORCID; Chioua, Mourad CSIC ORCID | artículo |
closedAccess | | 2017 | 5-Amino-6,7,8,9-Tetrahydrobenzo[b][1,8]Naphthyridin-2(1H)-One: The first Example of a new Family of HuperTacrines for Alzheimer's Disease Therapy | Balmori, Alfonso; Chioua, Mourad CSIC ORCID ; Bellacasa, R. P. de la; Estrada-Tejedor, R.; Ismaili, Lhassane; Marco-Contelles, José CSIC ORCID; Borrell, J. I. | artículo |
openAccess | | 2023 | 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases | Knez, D.; Diez-Iriepa, Daniel CSIC; Chioua, Mourad CSIC ORCID ; Gottinger, A.; Denic, M.; Chantegreil, F.; Nachon, F.; Brazzolotto, X.; Skrzypczak-Wiercioch, A.; Meden, A.; Pišlar, A.; Kos, J.; Žakelj, S.; Stojan, J.; Sałat, K.; Serrano, Julia CSIC ORCID CVN; Fernandez, Ana P.; Sánchez-García, A.; Martínez-Murillo, Ricardo CSIC ORCID; Binda, C.; López-Muñoz, F.; Gobec, S.; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2011 | A practical two-step synthesis of imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines | Sucunza Sáez, David CSIC ORCID; Samadi, Abdelouahid CSIC ORCID; Chioua, Mourad CSIC ORCID ; Silva, Daniel; Yunta, Cristina CSIC; Infantes, L. CSIC ORCID; Carmo Carreiras, M.; Soriano, Elena CSIC; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2017 | A Simple and Ecofriendly One-Pot Synthesis of Highly Substituted 3-Cyanopyridine-Quinoline Hybrids via a Triphenyphosphine-Catalyzed Multicomponent Reaction Under Mild Conditions | Ladraa, S; Chioua, Mourad CSIC ORCID ; Belfaitah, A. | artículo |
| | 2020 | Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy | Bautista-Aguilera, Óscar M. CSIC ORCID; Ismaili, Lhassane; Chioua, Mourad CSIC ORCID ; Andrys, R.; Schmidt, Monika; Bzonek, Petr; Martínez-Grau, Angeles; Beadle, C. D.; Vetman, T.; López-Muñoz, Francisco; Iriepa, Isabel; Refouvelet, Bernard; Musilek, Kamil; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2020 | Automated Synthesis of New Quinoxalinetacrines | Bautista-Aguilera, Óscar M. CSIC ORCID; Ismaili, L.; Chioua, Mourad CSIC ORCID ; Iriepa, Isabel; Martínez-Grau, Angeles; Beadle, C. D.; Vetman, T.; López-Muñoz, Francisco; Marco-Contelles, José CSIC ORCID | artículo |
openAccess | | 31-mar-2020 | Characterization of a cholesteroNitrone (ISQ-201), a novel drug candidate for the treatment of ischemic stroke | Martínez-Alonso, Emma; Escobar-Peso, Alejandro CSIC ORCID; Ayuso, María I. CSIC ORCID; Gonzalo-Gobernado, Rafael CSIC ORCID; Chioua, Mourad CSIC ORCID ; Montoya, Juan J.; Montaner, Joan CSIC ORCID; Fernández, Israel; Marco-Contelles, José CSIC ORCID; Alcázar, Alberto | artículo |
closedAccess | | 2015 | CholesteroNitrones for Stroke | Ayuso, M. I.; Chioua, Mourad CSIC ORCID ; Martínez-Alonso, E.; Soriano, Elena CSIC; Montaner, Joan CSIC ORCID; Masjuán, J.; Hadjipavlou-Litina, Dimitra; Marco-Contelles, José CSIC ORCID; Alcázar, Alberto | artículo |
openAccess | | 1-jun-2011 | Compuestos derivados de 1,8-naftiridinas y su uso en el tratamiento de enfermedades neurodegenerativas | Romero Martínez, Alejandro; García García, Antonio; García López, Manuela; Egea, Javier; Chioua, Mourad CSIC ORCID ; Villarroya Sánchez, Mercedes; Soriano, Elena CSIC; León, Rafael CSIC ORCID ; Marco-Contelles, José CSIC ORCID; Ríos Salgado, Cristóbal; Samadi, Abdelouahid CSIC ORCID | solicitud de patente |
closedAccess | | 2015 | Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer’s disease | Chioua, Mourad CSIC ORCID ; Pérez, Marta M.; Bautista-Aguilera, Óscar M. CSIC ORCID; Yáñez, M.; López, M. G.; Romero, A.; Cacabelos, Ramón; Bellacasa, R. P. de la; Brogi, S.; Butini, S.; Borrell, J. I.; Marco-Contelles, José CSIC ORCID | artículo |
openAccess | | 24-mar-2016 | Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer's Disease Therapy | Boulebd, Houssem; Ismaili, L.; Bartolini, Manuela; Bouraiou, Abdelmalek; Andrisano, Vincenza; Martin, Hélène; Bonet, Alexandre; Moraleda, Ignacio; Iriepa, Isabel; Chioua, Mourad CSIC ORCID ; Belfaitah, Ali; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2015 | Isoxazolotacrines as non-toxic and selective butyrylcholinesterase inhibitors for Alzheimer's disease | Cherif, O.; Allouche, F.; Chabchoub, Fakher; Chioua, Mourad CSIC ORCID ; Soriano, Elena CSIC; Yáñez, Matilde; Cacabelos, Ramón; Romero, A.; López, M. G.; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2015 | α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: Synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties | Chioua, Mourad CSIC ORCID ; Sucunza, D.; Soriano, Elena CSIC; Hadjipavlou-Litina, Dimitra; Alcázar González, Alberto; Ayuso, I.; Oset-Gasque, María Jesús; Gonzalez, M. P.; Monjas, Leticia CSIC ORCID; Rodríguez-Franco, María Isabel CSIC ORCID ; Marco-Contelles, José CSIC ORCID; Marco-Contelles, José CSIC ORCID; Samadi, Abdelouahid CSIC ORCID | artículo |
openAccess | | 2014 | Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: Design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids | Bautista-Aguilera, Óscar M. CSIC ORCID; Esteban, Gerard; Chioua, Mourad CSIC ORCID ; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Soriano, Elena CSIC; Samadi, Abdelouahid CSIC ORCID; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2017 | Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases | Bautista-Aguilera, Óscar M. CSIC ORCID; Hagenow, S.; Palomino-Antolín, Alejandra; Farré-Alins, V.; Ismaili, L.; Joffrin, P. L.; Jimeno, M. Luisa CSIC ORCID; Soukup, Ondrej; Janockova, Jana; Kalinowski, A.; Proschak, E.; Iriepa, Isabel; Moraleda, I.; Schwed, J. S.; Romero, Alejandro CSIC ORCID; López-Muñoz, Francisco; Chioua, Mourad CSIC ORCID ; Egea, Javier; Ramsay, R. R.; Marco-Contelles, José CSIC ORCID; Stark, H. | artículo |
closedAccess | | 2014 | N-(furan-2-ylmethyl)-N-methylprop-2-yn-1-amine (F2MPA): A potential cognitive enhancer with MAO inhibitor properties | Di Giovanni, Giuseppe; García, Isela; Colangeli, Roberto; Pierucci, Massimo; Rivadulla, Marcos L.; Soriano, Elena CSIC; Chioua, Mourad CSIC ORCID ; Della Corte, Laura; Yáñez, Matilde; De Deurwaerdère, Phillippe; Fall, Yagamare; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2016 | N-Benzylpiperidine derivatives as α7 nicotinic receptor antagonists | Criado, Manuel CSIC ORCID; Mulet, José CSIC ORCID; Sala, Francisco CSIC ORCID; Sala, Salvador CSIC ORCID; Colmena, Inés CSIC; Gandía, Luis; Bautista-Aguilera, Oscar M.; Samadi, Abdelouahid CSIC ORCID; Chioua, Mourad CSIC ORCID ; Marco-Contelles, José CSIC ORCID | artículo |
closedAccess | | 2014 | N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor | Bautista-Aguilera, Óscar M. CSIC ORCID; Samadi, Abdelouahid CSIC ORCID; Chioua, Mourad CSIC ORCID ; Nikolic, K.; Filipic, S.; Agbaba, Danica; Soriano, Elena CSIC; Andrés, Lucía de CSIC; Rodríguez-Franco, María Isabel CSIC ORCID ; Alcaro, S.; Ramsay, R. R.; Ortuso, F.; Yáñez, Matilde; Marco-Contelles, José CSIC ORCID | artículo |
openAccess | | jul-2023 | Neuroprotective and Antioxidant Properties of CholesteroNitrone ChN2 and QuinolylNitrone QN23 in an Experimental Model of Cerebral Ischemia: Involvement of Necrotic and Apoptotic Cell Death | Chamorro, Beatriz; Izquierdo-Bermejo, Sara; Martín de Saavedra, María Dolores; López-Muñoz, Francisco; Chioua, Mourad CSIC ORCID ; Marco-Contelles, José CSIC ORCID; Oset-Gasque, María Jesús | artículo |