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openAccess17 Naunyn Sch Arch Pharmacol THI preprint-1.pdf.jpg13-Apr-20172-Acetyl-5-tetrahydroxybutyl imidazole (THI) protects 661W cells against oxidative stressFabiani, Carlotta; Zulueta, Aida; Bonezzi, Fabiola Tecla; Casas, Josefina CSIC ORCID ; Ghidoni, Riccardo; Signorelli, Paola; Caretti, Annaartículo
closedAccess20102-Aminohydroxamic acid derivatives as inhibitors of Bacillus cereus phosphatidylcholine preferred phospholipase C PC-PLCBcGonzález-Bulnes, Patricia CSIC; González-Roura, Albert; Canals, Daniel CSIC ORCID; Delgado Cirilo, Antonio CSIC ORCID; Casas, Josefina CSIC ORCID ; Llebaria, Amadeu CSIC ORCIDartículo
openAccessC5MB00852B_postprint.pdf.jpg22-Apr-20163-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells.Ordóñez, Yadira F.; González, Jèssica; Bedia, Carmen CSIC ORCID; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
openAccessMar-2024A fluorogenic substrate for the detection of lipid amidases in intact cellsCasasampere, Mireia CSIC ORCID; Ung, Johnson; Iñáñez, Alejandro; Dufau, Carine; Tsuboi, Kazuhito; Casas, Josefina CSIC ORCID ; Tan, Su-Fern; Feith, David J.; Andrieu-Abadie, Nathalie; Segui, Bruno; Loughran, Thomas P.; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID artículo
openAccessA Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor.pdf.jpg17-Jan-2020A Mechanism-Based Sphingosine-1-phosphate Lyase InhibitorPons, Guillem; Riba, Daniel; Casasampere, Mireia CSIC ORCID; Izquierdo, Eduardo; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Rodríguez Ortega, Pilar G.; Montejo, Manuel; López González, Juan J.; Casas, Josefina CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCIDartículo
closedAccess2010Absorption and metabolization of cytoprotective epicatechin thio conjugates in rats.Selga, Ariadna CSIC; Vinardell, M. Pilar CSIC ORCID; Martín-Venegas, Raquel; Jáuregui, Olga; Casas, Josefina CSIC ORCID ; Torres, Josep Lluís CSIC ORCIDartículo
openAccess1-s2.0-S0006349512003311-main.pdf.jpg2012Accumulated bending energy elicits neutral sphingomyelinase activity in human red blood cellsLópez, David J. CSIC ORCID; Egido-Gabas, Meritxell; López-Montero, Iván; Busto, Jon V. CSIC; Casas, Josefina CSIC ORCID ; Garnier, Marie; Monroy, Francisco; Larijani, Banafshé CSIC ORCID; Goñi, Félix M. CSIC ORCID; Alonso, Alicia CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg19-Feb-2013Acid ceramidase as a therapeutic target in metastatic prostate cancerCamacho, Luz CSIC ORCID; Meca-Cortés, Óscar CSIC ORCID; Abad, José Luis CSIC ORCID ; García, Simón CSIC; Rubio, Nuria CSIC; Celià-Terrassa, Toni CSIC ORCID; Cingolani, Francesca CSIC; Blanco, Jerónimo CSIC ORCID; Delgado Cirilo, Antonio CSIC ORCID; Casas, Josefina CSIC ORCID ; Thomson, Timothy M. CSIC ORCID artículo
openAccessAcid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities.pdf.jpg1-Apr-2017Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System AbnormalitiesSikora, Jakub; Casas, Josefina CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Walkley, Steven U.artículo
closedAccess2011Acid Ceramidase Expression Modulates the Sensitivity of A375 Melanoma Cells to DacarbazineBedia, Carmen CSIC ORCID; Casas, Josefina CSIC ORCID ; Andrieu-Abadie, Nathalie; Fabriàs, Gemma CSIC ORCID ; Levade, Thierryartículo
openAccess1-s2.0-S2213231721002111-main.pdf.jpgSep-2021Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulationTorres, Sandra CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Matías, Nuria CSIC; Insausti, Naroa CSIC ORCID; Castro, Fernanda; Casasempere, Mireia; Fabriàs, Gemma CSIC ORCID ; Casas, Josefina CSIC ORCID ; Enrich, Carlos; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
openAccessActivity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiols.pdf.jpg1-Oct-2015Activity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiolsCasasampere, Mireia CSIC ORCID; Camacho, Luz CSIC ORCID; Casas, Josefina CSIC ORCID ; Cingolani, Francesca CSIC; Egido-Gabás, Meritxell CSIC; Abad, José Luis CSIC ORCID ; Bedia, Carmen CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
openAccess28-Apr-2019Activity-Based Imaging of Acid Ceramidase in Living CellsOrdóñez, Yadira F.; Abad, José Luis CSIC ORCID ; Aseeri, Mazen; Casas, Josefina CSIC ORCID ; Garcia, Virginie; Casasampere, Mireia CSIC ORCID; Schuchman, Edward H.; Levade, Thierry; Delgado Cirilo, Antonio CSIC ORCID; Triola Guillem, Gemma CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
openAccessÁvilaJ_Adeno-associatedViral.pdf.jpg21-Aug-2019Adeno-associated viral vector serotype 9-based gene therapy for Niemann-Pick disease type ASamaranch, Lluís; Pérez-Cañamás, Azucena; Soto-Huelin, Beatriz; Sudhakar, Vivek; Jurado-Arjona, Jerónimo CSIC; Hadaczek, Piotr; Ávila, Jesús CSIC ORCID ; Bringas, John R.; Casas, Josefina CSIC ORCID ; Chen, Haifeng; He, Xingxuan; Schuchman, Edward Howard; Cheng, Seng H.; Forsayeth, John; Bankiewicz, Krystof S.; Ledesma, M. Dolores CSIC ORCIDartículo
openAccessAAV9-based gene therapy for Niemann-Pick disease type A.pdf.jpg21-Aug-2019Adeno-associated viral vector serotype 9-based gene therapy for Niemann-Pick disease type ASamaranch, Lluís; Pérez-Cañamás, Azucena; Soto-Huelin, Beatriz; Sudhakar, Vivek; Jurado-Arjona, Jerónimo CSIC; Hadaczek, Piotr; Ávila, Jesús CSIC ORCID ; Bringas, John R.; Casas, Josefina CSIC ORCID ; Chen, Haifeng; He, Xingxuan; Schuchman, Edward Howard; Cheng, Seng H.; Forsayeth, John R.; Bankiewicz, Krystof S.; Ledesma, M. Dolores CSIC ORCIDartículo
openAccessES2396092A1.pdf.jpg19-Feb-2013Amidas de 2-amino-1,3-propanodioles y su uso como inhibidores de ceramidasasAbad, José Luis CSIC ORCID ; Camacho, Luz CSIC ORCID; Casas, Josefina CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Garrido, María CSIC; Thomson, Timothy M. CSIC ORCID ; Meca-Cortés, Óscar CSIC ORCID; Delgado Cirilo, Antonio CSIC ORCIDsolicitud de patente
openAccessWO2013004871A1.pdf.jpg10-Jan-2013Amides of 2-amino-1,3-propanediols and use thereof as ceramidase inhibitorsAbad, José Luis CSIC ORCID ; Camacho, Luz CSIC ORCID; Casas, Josefina CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Garrido, María CSIC; Thomson, Timothy M. CSIC ORCID ; Meca-Cortés, Óscar CSIC ORCID; Delgado Cirilo, Antonio CSIC ORCIDpatente
closedAccess4-May-2007Aminocyclitols as Pharmacological Chaperones for Glucocerebrosidase, a Defective Enzyme in Gaucher DiseaseEgido-Gabás, Meritxell CSIC; Canals, Daniel CSIC ORCID; Casas, Josefina CSIC ORCID ; Llebaria, Amadeu CSIC ORCID; Delgado Cirilo, Antonio CSIC ORCIDartículo
closedAccessBedia_Carmen_et_al.pdf.jpg8-Sep-2005Analogs of the dihydroceramide desaturase inhibitor GT11 modified at the amide function: synthesis and biological activitiesBedia, Carmen CSIC ORCID; Triola Guillem, Gemma CSIC ORCID; Casas, Josefina CSIC ORCID ; Llebaria, Amadeu CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
openAccess22-Nov-2012Analysis of sphingolipids by UPLC-TOFCasas, Josefina CSIC ORCID actas de congreso