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openAccessijms-25-00051-v3.pdf.jpgJan-20243′dNTP Binding Is Modulated during Primer Synthesis and Translesion by Human PrimPolVelázquez-Ruiz, Cristina; Blanco, Luis CSIC ORCID ; Martínez-Jiménez, María I. CSIC ORCID artículo
openAccessBlancoL_ACancer-Associated.pdf.jpg4-Feb-2019A cancer-associated point mutation disables the steric gate of human PrimPolDíaz-Talavera, Alberto CSIC ORCID; Calvo, Patricia A.; González-Acosta, Daniel; Díaz, Marcos; Sastre-Moreno, Guillermo; Blanco-Franco, Luis; Guerra, Susana; Martínez-Jiménez, María I. CSIC ORCID ; Méndez, Juan; Blanco, Luis CSIC ORCID artículo
openAccessBlancoL_A uniqueArginineCluster.pdf.jpg19-Jan-2021A unique arginine cluster in PolDIP2 enhances nucleotide binding and DNA synthesis by PrimPolKasho, Kazutoshi; Stojkovic, Gorazd; Velázquez-Ruiz, Cristina; Martínez-Jiménez, María I. CSIC ORCID ; Doimo, Mara; Laurent, Timothée; Berner, Andreas; Pérez-Rivera, Aldo E.; Jenninger, Luoise; Blanco, Luis CSIC ORCID ; Wanrooij, Sjoerdartículo
openAccessBlanco L Alternative solutions.pdf.jpg23-Feb-2015Alternative solutions and new scenarios for translesion DNA synthesis by human PrimPolMartínez-Jiménez, María I. CSIC ORCID ; García-Gómez, Sara CSIC; Bebenek, Katarzyna; Sastre-Moreno, Guillermo; Calvo, Patricia A.; Díaz-Talavera, Alberto CSIC ORCID; Kunkel, Thomas A.; Blanco, Luis CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg31-Aug-2014Characterization of the primase and polymerase activieties of human PrimPolMartínez-Jiménez, María I. CSIC ORCID ; García-Gómez, Sara CSIC; Chocrón, Sandra CSIC; Díaz-Talavera, Alberto CSIC ORCID; Calvo, Patricia A.; Blanco, Luis CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpg8-Sep-2011DNA polimerasa theta de Leishmania infantum: Localización y actividadFernández, A.; Alonso Ayala, Ana María; Martínez-Jiménez, María I. CSIC ORCID ; Blanco, Luis CSIC ORCID ; Larraga, Vicente CSIC ORCID póster de congreso
openAccessBlancoL_EngineeringHUmanPrimpol.pdf.jpg12-Jul-2017Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymeraseAgudo, Rubén CSIC ORCID; Calvo, Patricia A.; Martínez-Jiménez, María I. CSIC ORCID ; Blanco, Luis CSIC ORCID artículo
openAccessBlancoL_HumanPrimPolActivity.pdf.jpg10-Apr-2017Human PrimPol activity is enhanced by RPAMartínez-Jiménez, María I. CSIC ORCID ; Lahera, Antonio; Blanco, Luis CSIC ORCID artículo
openAccessBlancoL_PrimPol-mediatedRepriming.pdf.jpg24-Sep-2021Human primpol discrimination against dideoxynucleotides during primer synthesisCarvalho, Gustavo; Díaz-Talavera, Alberto CSIC ORCID; Calvo, Patricia A.; Blanco, Luis CSIC ORCID ; Martínez-Jiménez, María I. CSIC ORCID artículo
openAccessIdentification_of_West_Nile_virus.pdf.jpgApr-2023Identification of West Nile virus RNA-dependent RNA polymerase non-nucleoside inhibitors by real-time high throughput fluorescence screeningGarcía-Zarandieta, Marta; Quesada, Ernesto CSIC ORCID ; Martínez-Jiménez, María I. CSIC ORCID ; Newnes, Cristina V; Fernández-Cabello, Víctor CSIC; Saez-Alvarez, Yanira; Blázquez, Ana B.; Escribano-Romero, Estela; Saiz Calahorra, Juan Carlos; Del Aguila, Carmen; Martín-Acebes, M. A.; Peréz-Pérez, María-Jesús CSIC ORCID ; Agudo, Rubenartículo
openAccessBlancoL_IdentifyingTheRole.pdf.jpg2020Identifying the role of PrimPol in TDF-induced toxicity and implications of its loss of function mutation in an HIV+ patientDuong, Vicent N.; Zhou, Lei; Martínez-Jiménez, María I. CSIC ORCID ; He, Linh; Cosme, Moises; Blanco, Luis CSIC ORCID ; Paintsil, Elijah; Anderson, Karenartículo
openAccessBlancoL_MechanismofDNArimer.pdf.jpg2019Mechanism of DNA primer synthesis by human PrimPolBlanco, Luis CSIC ORCID ; Clavo, Patricia A.; Díaz-Talavera, Alberto CSIC ORCID; Carvalho, Gustavo; Calero, Nieves; Velázquez-Ruiz, Cristina; Villadangos, Sabina; Guerra, Susana; Martínez-Jiménez, María I. CSIC ORCID ; Martínez-Carrón, Anaartículo
openAccessBlancoL_NAR_1366.pdf.jpg7-Oct-2011Molecular architecture of a multifunctional MCM complexSánchez-Berrondo, June; Mesa, Pablo; Ibarra, Arkaitz; Martínez-Jiménez, María I. CSIC ORCID ; Blanco, Luis CSIC ORCID ; Méndez, Juan; Boskovic, Jasminka; Montoya, Guillermoartículo
closedAccessaccesoRestringido.pdf.jpg23-May-2022Motif B and Lys297 are required to stabilize 3¿ incoming deoxynucleotides by human PrimPolVelázquez-Ruiz, Cristina; Martínez-Jiménez, María I. CSIC ORCID ; Blanco, Luis CSIC ORCID póster de congreso
openAccessBlancoL_Motif WFYYofHumanPrimPol.pdf.jpg12-Jul-2021Motif WFYY of human PrimPol is crucial to stabilize the incoming 3′-nucleotide during replication fork restartCalvo, Patricia A.; Martínez-Jiménez, María I. CSIC ORCID ; Díaz, Marcos; Stojkovic, Gorazd; Kasho, Kazutoshi; Guerra, Susana; Wanrooij, Sjoerd; Méndez, Juan; Blanco, Luis CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg9-Sep-2014Mutational Analysis and Characterization of WFYY Motif in human PrimPolCalvo, Patricia A.; Díaz, Marcos ; Martínez-Jiménez, María I. CSIC ORCID ; Mourón, Silvana; Guerra, Susana; Méndez, Juan; Blanco, Luis CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpg4-Sep-2012PrimPol a two in one enzyme: primase and bypass polymeraseGarcía-Gómez, Sara CSIC; Martínez-Jiménez, María I. CSIC ORCID ; Blanco, Luis CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpg24-Sep-2017PrimPol does not get along with dideoxynucleotidesCarvalho, Gustavo; Martínez-Jiménez, María I. CSIC ORCID ; Blanco, Luis CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpg3-Mar-2013PrimPol, a new human DNA primase/polymerase, is involved in translesion synthesis and recovery of stalled forks during nuclear DNA replicationMéndez, Juan; Mourón, Silvana; Rodríguez-Acebes, Sara; García-Gómez, Sara CSIC; Martínez-Jiménez, María I. CSIC ORCID ; Chocrón, Sandra CSIC; Blanco, Luis CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpg3-Sep-2013PrimPol, a new player in translesion synthesis during DNA replicationMartínez-Jiménez, María I. CSIC ORCID ; García-Gómez, Sara CSIC; Díaz-Talavera, Alberto CSIC ORCID; Calvo, Patricia A.; Blanco, Luis CSIC ORCID póster de congreso