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RightsPreviewIssue DateTitleAuthor(s)Type
openAccessTlympho.pdf.jpg2007A new role of diacylglycerol kinase α on the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytesAlonso, Roberto ; Mazzeo, C. ; Mérida, Isabel ; Izquierdo, Manuel  artículo
closedAccessaccesoRestringido.pdf.jpgJan-2020Biological regulation of diacylglycerol kinases in normal and neoplastic tissues: New opportunities for cancer immunotherapyArranz Nicolás, Javier; Mérida, Isabel artículo de revisión
closedAccessaccesoRestringido.pdf.jpg2020Diacylglycerol Kinase Malfunction in Human Disease and the Search for Specific InhibitorsMérida, Isabel ; Arranz Nicolás, Javier; Torres Ayuso, Pedro; Ávila-Flores, Antoniacapítulo de libro
closedAccessaccesoRestringido.pdf.jpg14-Apr-2020Diacylglycerol kinase ¿ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapseMerino-Cortés, Sara V.; Gardeta, Sofía; Román-García, Sara; Martínez-Riaño, Ana; Pineau, Judith; Liébana, Rosa; Mérida, Isabel ; Lennon Dumenil, Ana-María; Pierobon, Paolo; Husson, Julien; Alarcón, Balbino ; Carrasco, Yolanda R.artículo
openAccessMAÑES, S. - Cancer Immun. Immunother. - 2018.pdf.jpgJun-2018Diacylglycerol kinase α inactivation is an integral component of the costimulatory pathway that amplifies TCR signalsArranz Nicolás, Javier; Ogando, Jesús; Soutar, Denise; Arcos Pérez, Raquel; Meraviglia Crivelli, Daniel; Mañes, Santos; Mérida, Isabel ; Ávila Flores, Antoniaartículo
openAccessDiacylglycerol kinase.pdf.jpg2014Diacylglycerol kinase α promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with SrcTorres Ayuso, Pedro; Daza-Martín, Manuel; Martín-Pérez, Jorge  ; Ávila-Flores, Antonia; Mérida, Isabel artículo
openAccess2011Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytesAlonso, Roberto ; Mazzeo, C. ; Rodríguez, María del Carmen ; Fraile-Ramos, Alberto; Calvo, Victor ; Ávila-Flores, Antonia; Mérida, Isabel ; Izquierdo, Manuel  artículo
closedAccess2005Diacylglycerol kinase α regulates the secretion of lethal exosomes bearing fas ligand during activation-induced cell death of T lymphocytesAlonso, Roberto ; Rodríguez, María del Carmen ; Pindado, José ; Merino Plaza, Ernesto; Mérida, Isabel ; Izquierdo, Manuel  artículo
openAccessDiacylglycerol_Arranz_PV_Art2020.pdf.jpg2020Diacylglycerol kinase ζ limits IL-2-dependent control of PD-1 expression in tumor-infiltrating T lymphocytesArranz Nicolás, Javier; Martin-Salgado, Miguel; Rodríguez-Rodríguez, Cristina; Liébana, Rosa; Moreno-Ortiz, María C.; Leitner, Judith; Steinberger, Peter; Ávila-Flores, Antonia; Mérida, Isabel artículo
closedAccessAntigen_receptor_signaling_Press_release.pdf.jpg28-Jun-2009Essential function for the GTPase TC21 in homeostatic antigen receptor signalingDelgado, Pilar ; Cubelos, Beatriz ; Calleja, Enrique; Martínez-Martín, Nuria ; Ciprés, Ángel; Mérida, Isabel ; Bustelo, Xosé R.  ; Alarcón, Balbino artículo
openAccessInterplay_González_Mancha_Art2020.pdf.jpg15-Jun-2020Interplay Between SNX27 and DAG Metabolism in the Control of Trafficking and Signaling at the ISGonzález-Mancha, Natalia; Mérida, Isabel artículo
openAccessproof-3.pdf.jpgMay-2008Lck-Dependent Tyrosine Phosphorylation of Diacylglycerol Kinase {alpha} Regulates Its Membrane Association in T CellsMerino Plaza, Ernesto; Ávila Flores, Juana Antonia; Shiriai, Yasuhito; Moraga, Ignacio; Saito, Naoaki; Mérida, Isabel artículo
openAccess206.pdf.jpgSep-1996Linomide prevents the lethal effect of anti-fas antibody and reduces fas-mediated ceramide production in mouse hepatocytesRedondo, Clara; Flores, Ignacio ; González García, Ana; Nagata, Shigekazu; Carrera, Ana C.; Mérida, Isabel ; Martínez-Alonso, Carlosartículo
openAccessWO2008148926A2.pdf.jpg11-Dec-2008Method for diagnosing immune system diseases and compounds that can be used to treat said diseasesMérida, Isabel ; Merino Plaza, Ernesto; Saito, Naoaki; Shiriai, Yasuhito; Kakehi, Tomoko; Matsubara, Takehiro; Ávila-Flores, Antoniapatente
openAccess2322422_B1.pdf.jpg6-Apr-2010Procedimiento de diagnóstico de enfermedades del sistema inmuneMérida, Isabel ; Merino Plaza, Ernesto; Saito, Naoaki; Shiriai, Yasuhito; Kakehi, Tomoko; Matsubara, Takehiro; Ávila-Flores, Antoniapatente
openAccessPKd1-2.pdf.jpg2015Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytesMazzeo, C. ; Calvo, Victor ; Alonso, Roberto ; Mérida, Isabel ; Izquierdo, Manuel  artículo
openAccessProtooncogenes.pdf.jpgOct-1993Protooncogene-encoded protein kinases in interleukin-2 signal transductionReed, John C.; Torigoe, Toshihiko; Turner, Bruce C.; Mérida, Isabel ; Gaulton, Glen; Saragovi, H. Uri; Rapp, Ulf R.; Taichman, Russellartículo
openAccessRole of Diacylglycerol.pdf.jpg2001Role of diacylglycerol kinase α in the attenuation of receptor signalingSanjuán, Miguel Ángel; Jones, David R.; Izquierdo, Manuel  ; Mérida, Isabel artículo
closedAccessrestringido.pdf.jpg15-Mar-2003T Cell activation in vivo targets diacylglycerolk kinase  to the membrane: A novel mechanism for ras attenuationSanjuan, Miguel; Pradet-Balade, Bérengère; Jones, David R.; Martínez, Carlos; Stone, James C.; García-Sanz, José A.  ; Mérida, Isabel artículo
openAccess1539.pdf.jpgDec-2007Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movementLacalle, Rosa Ana; Peregil, Rosa M.; Albar, Juan Pablo; Merino Plaza, Ernesto; Martínez-Alonso, Carlos; Mérida, Isabel ; Mañes, Santosartículo