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RightsPreviewIssue DateTitleAuthor(s)Type
openAccessmicromachines-09-00129-v2.pdf.jpg15-Mar-2018A label free disposable device for rapid Isolation of rare tumor cells from blood by ultrasoundsGonzález, Itziar; Earl, Julie; Fernández, Luis J.; Sainz, Bruno Jr. ; Pinto, Alberto CSIC ORCID ; Monge, Rosa; Alcalá, Sonia; Castillejo, Adela; Soto, José L.; Carrato, Alfredo
openAccesscanstemcell.pdf.jpg2016Cancer stem cells and macrophages: implications in tumor biology and therapeutic strategiesSainz, Bruno Jr. ; Carron, Emily; Vallespinós, Mireia; Machado, Heather L.artículo
openAccessCROH17ReviSUB.pdf.jpg2018Current perspectives on the crosstalk between lung cancer stem cells and cancer-associated fibroblastsAlguacil-Núñez, Cristina; Ferrer-Ortiz, Inés; García-Verdú, Elena; López-Pirez, Pilar; Llorente-Cortijo, Irene Maria; Sainz, Bruno Jr. artículo
openAccess92Cluster.pdf.jpg2016DNMT1 inhibition reprograms pancreatic cancer stem cells via upregulation of the miR-17-92 clusterZagorac, Sladjana; Alcalá, Sonia; Fraga, Mario F.; Heeschen, Christopher; Sainz, Bruno Jr. artículo
openAccessEMTcells.pdf.jpg2019EMT and stemness—key players in pancreatic cancer stem cellsRodriguez-Aznar, Eva; Wiesmüller, Lisa; Sainz, Bruno Jr. ; Hermann, Patrick C.artículo
openAccessExploiting _Valle_PV_Ar2020.pdf.jpg2020Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cellsValle, Sandra; Alcalá, Sonia; Martin-Hijano, Laura; Cabezas-Sainz, Pablo; Navarro, Diego CSIC; Ramos, Edurne; Yuste Pérez, Lourdes; Tiwary, Kanishka; Walter, Karolin; Ruiz-Cañas, Laura; Alonso-Nocelo, Marta; Rubiolo, Juan A.; González-Arnay, Emilio; Heeschen, Christopher; García-Bermejo, María Laura; Hermann, Patrick C.; Sánchez, Laura; Sancho, Patricia; Fernández-Moreno, Miguel Ángel CSIC ORCID; Sainz, Bruno Jr. artículo
openAccessGlutathione_Jagust_PV_Art2020.pdf.jpg26-Nov-2020Glutathione metabolism is essential for self-renewal and chemoresistance of pancreatic cancer stem cellsJagust, Petra; Alcalá, Sonia; Sainz, Bruno Jr. ; Heeschen, Christopher; Sancho, Patriciaartículo
openAccessacinar-ductal.pdf.jpg2017Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modellingHohwieler, Meike; Illing, Anett; Hermann, Patrick C.; Mayer, Tobias; Stockmann, Marianne; Perkhofer, Lukas; Eiseler, Tim; Antony, Justin S.; Müller, Martin; Renz, Susanne; Kuo, Chao-Chung; Lin, Qiong; Sendler, Matthias; Breunig, Markus; Kleiderman, Susanne M.; Lechel, André; Zenker, Martin; Leichsenring, Michael; Rosendahl, Jonas; Zenke, Martin; Sainz, Bruno Jr. ; Mayerle, Julia; Costa, Ivan G.; Seufferlein, Thomas; Kormann, Michael; Wagner, Martin; Liebau, Stefan; Kleger, Alexanderartículo
openAccessInduction_Cash_PV_Art2020.pdf.jpg4-Jul-2020Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem CellsCash, Timothy P.; Alcalá, Sonia; Rico-Ferreira, María del Rosario; Hernandez-Encinas, Elena; García, Jennifer; Albarrán, María Isabel; Valle, Sandra; Muñoz, Javier CSIC; Martínez-González, Sonia; Blanco-Aparicio, Carmen; Pastor, Joaquín; Serrano, Manuel; Sainz, Bruno Jr. artículo
openAccessisgplasti.pdf.jpg2020ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticityAlcalá, Sonia; Sancho, Patricia; Martinelli, Paola; Navarro, Diego CSIC; Pedrero García, Coral; Martin-Hijano, Laura; Valle, Sandra; Earl, Julie; Rodríguez-Serrano, Macarena; Ruiz-Cañas, Laura; Rojas, Katerin; Carrato, Alfredo; García-Bermejo, María Laura; Fernández-Moreno, Miguel Ángel CSIC ORCID; Hermann, Patrick C.; Sainz, Bruno Jr. artículo
openAccessMEKvivo.pdf.jpg2019MEK inhibition targets cancer stem cells and impedes migration of pancreatic cancer cells in vitro and in vivoWalter, Karolin; Tiwary, Kanishka; Trajkovic-Arsic, Marija; Hidalgo-Sastre, Ana; Dierichs, Laura; Liffers, Sven T.; Gu, Jiangning; Gout, Johann; Schulte, Lucas-Alexander; Münch, Jan; Seufferlein, Thomas; Sainz, Bruno Jr. ; Siveke, Jens T.; Rodriguez-Aznar, Eva; Hermann, Patrick C.artículo
openAccessmodelmicro.pdf.jpg2020Modeling cancer using zebrafish xenografts: Drawbacks for mimicking the human microenvironmentCabezas-Sainz, Pablo; Pensado-López, Alba; Sainz, Bruno Jr. ; Sánchez, Lauraartículo
openAccesskrasphospha.pdf.jpg2018Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphataseRuess, Dietrich A.; Heynen, Guus J.; Ciecielski, Katrin J.; Ai, Jiaoyu; Berninger, Alexandra; Kabacaoglu, Derya; Görgülü, Kivanc; Dantes, Zhara; Wörmann, Sonja M.; Diakopoulos, Kalliope N.; Karpathaki, Angeliki F.; Kowalska, Marlena; López-Alberca, María P.; Nazaré, Marc; Reichert, Maximilian; Saur, Dieter; Erkan, Mert M.; Hopt, Ulrich T.; Sainz, Bruno Jr. ; Birchmeier, Walter; Schmid, Roland M.; Lesina, Marina; Algül, Hanaartículo
openAccesspancreaentity.pdf.jpg2018Pancreatic cancer stem cells: A state or an entity?Hermann, Patrick C.; Sainz, Bruno Jr. artículo
openAccesspancrespon.pdf.jpg2020Pancreatic cancer-derived organoids – a disease modeling tool to predict drug responseFrappart, Pierre-Olivier; Walter, Karolin; Gout, Johann; Beutel, Alica K.; Morawe, Mareen; Arnold, Frank; Breunig, Markus; Barth, Thomas F. E.; Marienfeld, Ralf; Schulte, Lucas-Alexander; Ettrich, Thomas; Hackert, Thilo; Svinarenko, Michael; Rösler, Reinhild; Wiese, Sebastian; Wiese, Heike; Perkhofer, Lukas; Müller, Martin; Lechel, André; Sainz, Bruno Jr. ; Hermann, Patrick C.; Seufferlein, Thomas; Kleger, Alexanderartículo
openAccessPartial_Lerma_Postprint_2020.pdf.jpg2020Partial complementation between the immediate early proteins ICP4 of herpes simplex virus type 1 and IE180 of pseudorabies virusLerma, L.; Muñoz, A. L.; García Utrilla, R.; Sainz, Bruno Jr. ; Tabarés, E.; Gómez Sebastián, Silviaartículo
openAccesspathodisor.pdf.jpg2018Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorderFriederich, Marisa W.; Timal, Sharita; Powell, Christopher A.; Dallabona, Cristina; Kurolap, Alina; Palacios-Zambrano, Sara; Bratkovic, Drago; Derks, Terry G. J.; Bick, David; Bouman, Katelijne; Chatfield, Kathryn C.; Damouny-Naoum, Nadine; Dishop, Megan K.; Falik-Zaccai, Tzipora C.; Fares, Fuad; Fedida, Ayalla; Ferrero, Ileana; Gallagher, Renata C.; Garesse, Rafael CSIC ORCID; Gilberti, Micol; Gónzalez, Cristina; Gowan, Katherine; Habib, Clair; Halligan, Rebecca K.; Kalfon, Limor; Knight, Kaz; Lefeber, Dirk; Mamblona, Laura; Mandel, Hanna; Mory, Adi; Ottoson, John; Paperma, Tamar; Prujin, Ger J. M.; Rebelo-Guiomar, Pedro F.; Saada, Ann; Sainz, Bruno Jr. ; Salvemini, Hayley; Schoots, Mirthe H.; Smeitink, Jan A.; Szukszto, Maciej J.; Horst, Hendrik J. ter; Brandt, Frans van den; Spronsen, Francjan J. van; Veltman, Joris A.; Wartchow, Eric; Wintjes, Liesbeth T.; Zohar, Yaniv; Fernández-Moreno, Miguel Ángel CSIC ORCID; Baris, Hagit N.; Donnini, Claudia; Minczuk, Michal; Rodenburg, Richard J.; Van Hove, Johan L.K.artículo
openAccessreducells.pdf.jpg2017Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cellsLuciene da Silva, Istéfani; Montero, Lucía; Martín-Villar, Ester CSIC ORCID; Martín-Pérez, Jorge CSIC ORCID ; Sainz, Bruno Jr. ; Renart, Jaime CSIC ORCID; Toscano Simões, Renata; Soares Veloso, Emerson; Salviano Teixeira, Cláudia; Oliveira, Mônica C. de; Ferreira, Enio; Quintanilla, Miguel CSIC ORCIDartículo
openAccess2020Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancerGout, Johann; Perkhofer, Lukas; Morawe, Mareen; Arnold, Frank; Ihle, Michaela; Biber, Stephanie; Lange, Sebastian; Roger, Elodie; Kraus, Johann M.; Stifter, Katja; Hahn, Stephan A.; Zamperone, Andrea; Engleitner, Thomas; Müller, Martin; Walter, Karolin; Rodriguez-Aznar, Eva; Sainz, Bruno Jr. ; Hermann, Patrick C.; Hessmann, Elisabeth; Müller, Sebastian; Azoitei, Ninel; Lechel, André; Liebau, Stefan; Wagner, Martin; Simeone, Diane M.; Kestler, Hans A.; Seufferlein, Thomas; Wiesmüller, Lisa; Rad, Roland; Frappart, Pierre-Olivier; Kleger, Alexanderartículo
openAccesstargetlines.pdf.jpg2020Targeting MAD2 modulates stemness and tumorigenesis in human Gastric Cancer cell linesPajuelo-Lozano, Natalia; Alcalá, Sonia; Sainz, Bruno Jr. ; Perona Abellón, Rosario CSIC ORCID; Sánchez-Pérez, Isabelartículo