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closedAccessaccesoRestringido.pdf.jpgFeb-2006A comparison of viral RNA-dependent RNA polymerasesFerrer-Orta, Cristina CSIC ; Arias, Armando CSIC ORCID CVN; Escarmís, Cristina ; Verdaguer, Núria CSIC ORCID artículo
openAccessAmulti_step_ProcessOfViralAdaptation.pdf.jpg2010A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escapeAgudo, Rubén CSIC; Ferrer-Orta, Cristina CSIC ; Arias, Armando CSIC ORCID CVN; Higuera, Ignacio de la CSIC ORCID; Perales, Celia CSIC ORCID; Pérez-Luque, Rosa CSIC ORCID ; Verdaguer, Núria CSIC ORCID ; Domingo, Esteban CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpgDec-2020Amino acid substitutions associated with treatment failure for Hepatitis C virus infectionSoria, María Eugenia; García-Crespo, Carlos; Martínez-González, Brenda; Vázquez-Sirvent, Lucía; Lobo-Vega, Rebeca; Ávila, Ana Isabel de; Gallego, Isabel CSIC ORCID; Chen, Qian; García-Cehic, Damir; Llorens-Revull, Meritxell; Briones, Carlos CSIC ORCID; Gómez, Jordi; Ferrer-Orta, Cristina CSIC ; Verdaguer, Núria CSIC ORCID ; Gregori, Josep; Rodríguez-Frías, Francisco; Buti, María; Esteban, Juan Ignacio; Domingo, Esteban CSIC ORCID; Quer, Josep; Perales, Celia CSIC ORCIDartículo
openAccesscis_trans_activities-Herod.pdf.jpg18-May-2016Both cis and trans activities of foot-and-mouth disease virus 3D polymerase are essential for viral RNA replicationHerod, Morgan R.; Ferrer-Orta, Cristina CSIC ; Loundras, Eleni-Anna; Ward, Joseph C.; Verdaguer, Núria CSIC ORCID ; Rowlands, David J.; Stonehouse, Nicola J.artículo
closedAccessaccesoRestringido.pdf.jpg2012Conformational changes in motif d of RdRPs as fidelity determinantVerdaguer, Núria CSIC ORCID ; Ferrer-Orta, Cristina CSIC artículo
openAccessMultifunctuional_poly-post-print.pdf.jpgOct-2018Contribution of a multifunctional polymerase region of foot-and-mouth disease virus to lethal mutagenesisHiguera, Ignacio de la CSIC ORCID; Ferrer-Orta, Cristina CSIC ; Moreno, Elena CSIC; Ávila, Ana Isabel de; Soria, María Eugenia; Singh, Kamalendra; Flavia Caridi,; Sobrino, Francisco; Sarafianos, Stefan G.; Perales, Celia CSIC ORCID; Verdaguer, Núria CSIC ORCID ; Domingo, Esteban CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg4-Oct-2021Coupled sterol synthesis and transport machineries at ER-endocytic contact sitesEncinar del Dedo, Javier CSIC ORCID ; Fernández-Golbano, Isabel María CSIC ORCID ; Pastor González, Laura; Meler, Paula; Ferrer-Orta, Cristina CSIC ; Rebollo, Elena CSIC ORCID ; Geli, María Isabel CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg14-Oct-2014Design, synthesis and X-Ray of Foot-and-mouth disease virus (Fluoro)uridylylated peptides linked to the genome (VPgpU and VPgpFU)Castro, Sonia de; Ferrer-Orta, Cristina CSIC ; Fernández-Cureses, Gloria CSIC; Verdaguer, Núria CSIC ORCID ; Domingo, Esteban CSIC ORCID; Camarasa Rius, María José CSIC ORCIDpóster de congreso
closedAccessaccesoRestringido.pdf.jpg18-Sep-2016(F)Uridylylated peptides linked to the viral Protein VPg1 of foot-and-mouth disease virusCamarasa Rius, María José CSIC ORCID; Castro, Sonia de; Ferrer-Orta, Cristina CSIC ; Verdaguer, Núria CSIC ORCID ; Gago, F.póster de congreso
openAccessmolecules-24-02360.pdf.jpg2019(F)uridylylated peptides linked to VPg1 of foot-and-mouth disease virus (FMDV): Design, synthesis and X-Ray crystallography of the complexes with FMDV RNA-Dependent RNA PolymeraseCastro, Sonia de; Ferrer-Orta, Cristina CSIC ; Mills, A.; Fernández-Cureses, Gloria CSIC; Gago, Federico CSIC ORCID; Verdaguer, Núria CSIC ORCID ; Camarasa Rius, María José CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg25-Jun-2013Mechanism for VPg inhibition by FUTP in foot-and-mouth disease virusCastro, Sonia de; Ferrer-Orta, Cristina CSIC ; Fernández-Cureses, Gloria CSIC; Verdaguer, Núria CSIC ORCID ; Domingo, Esteban CSIC ORCID; Camarasa Rius, María José CSIC ORCIDpóster de congreso
closedAccessaccesoRestringido.pdf.jpg3-Nov-2012Mechanism for VPg inhibition by FUTP in foot-and-mouth disease virusCastro, Sonia de; Ferrer-Orta, Cristina CSIC ; Fernández-Cureses, Gloria CSIC; Verdaguer, Núria CSIC ORCID ; Domingo, Esteban CSIC ORCID; Camarasa Rius, María José CSIC ORCIDpóster de congreso
openAccessMolecular_Higuera.pdf.jpg1-May-2017Molecular and functional bases of selection against a mutation bias in an RNA virusHiguera, Ignacio de la CSIC ORCID; Ferrer-Orta, Cristina CSIC ; Ávila, Ana Isabel de; Perales, Celia CSIC ORCID; Sierra, Macarena; Singh, Kamalendra; Sarafianos, Stefan G.; Dehouck, Yves; Bastolla, Ugo CSIC ORCID; Verdaguer, Núria CSIC ORCID ; Domingo, Esteban CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg23-Apr-2015Multifunctionality of a picornavirus polymerase domain: Nuclear localization signal and nucleotide recognitionFerrer-Orta, Cristina CSIC ; Higuera, Ignacio de la CSIC ORCID; Caridi, Flavia CSIC ORCID; Sánchez Aparicio, M. Teresa; Moreno, Elena CSIC; Perales, Celia CSIC ORCID; Singh, Kamalendra; Sarafianos, Stefan G.; Sobrino, Francisco; Domingo, Esteban CSIC ORCID; Verdaguer, Núria CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg11-Nov-2005Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA bindingArias, Armando CSIC ORCID CVN; Agudo, Rubén CSIC; Ferrer-Orta, Cristina CSIC ; Pérez-Luque, Rosa CSIC ORCID ; Airaksinen, Antero; Brocchi, Emiliana; Domingo, Esteban CSIC ORCID; Verdaguer, Núria CSIC ORCID ; Escarmís, Cristina artículo
closedAccessaccesoRestringido.pdf.jpg2010Mutation, quasispecies and lethal mutagenesisDomingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCID; Agudo, Rubén CSIC; Arias, Armando CSIC ORCID CVN; Escarmís, Cristina ; Ferrer-Orta, Cristina CSIC ; Verdaguer, Núria CSIC ORCID capítulo de libro
openAccessFerrer-Orta-Viruses-2015-v7-p4438.pdf.jpg6-Aug-2015RNA-dependent RNA polymerases of picornaviruses: From the structure to regulatory mechanismsFerrer-Orta, Cristina CSIC ; Ferrero, Diego CSIC ORCID ; Verdaguer, Núria CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2013Role of motif B loop in allosteric regulation of RNA-dependent RNA polymerization activityGarriga, Damià; Ferrer-Orta, Cristina CSIC ; Querol-Audí, Jordi CSIC; Oliva, Baldo; Verdaguer, Núria CSIC ORCID artículo
openAccessspectrum.00221-22.pdf.jpg29-Mar-2022SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease OutcomesMartínez-González, Brenda; Soria, María Eugenia; Vázquez-Sirvent, Lucía; Ferrer-Orta, Cristina CSIC ; Lobo-Vega, Rebeca; Mínguez, Pablo; Fuente, Lorena de la; Llorens, Carlos; Soriano, Beatriz; Ramos-Ruiz, Ricardo; Cortón, Marta; López-Rodríguez, Rosario; García-Crespo, Carlos; Gallego, Isabel CSIC ORCID; Ávila, Ana Isabel de; Gómez, Jordi; Enjuanes Sánchez, Luis CSIC ORCID ; Salar-Vidal, Llanos; Esteban, Jaime; Fernández-Roblas, Ricardo; Gadea, Ignacio; Ayuso, Carmen; Ruíz-Hornillos, Javier;; Verdaguer, Núria CSIC ORCID ; Domingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCIDartículo
openAccessSARS-CoV-2 Point Mutation and Deletion Spectra.pdf.jpg12-Jan-2022SARS-CoV-2 Point Mutation and Deletion Spectra, and Their Association with Different Disease OutcomeMartínez-González, Brenda; Soria, María Eugenia; Vázquez-Sirvent, Lucía; Ferrer-Orta, Cristina CSIC ; Lobo-Vega, Rebeca; Mínguez, Pablo; Fuente, Lorena de la; Llorens, Carlos; Soriano, Beatriz; Ramos-Ruiz, Ricardo; Cortón, Marta; López-Rodríguez, Rosario; García-Crespo, Carlos; Gallego, Isabel CSIC ORCID; Ávila, Ana Isabel de; Gómez, Jordi; Enjuanes Sánchez, Luis CSIC ORCID ; Salar-Vidal, Llanos; Esteban, Jaime; Fernández-Roblas, Ricardo; Gadea, Ignacio; Ayuso, Carmen; Ruíz-Hornillos, Javier; Verdaguer, Núria CSIC ORCID ; Domingo, Esteban CSIC ORCID; Perales, Celia CSIC ORCIDpreprint