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openAccess2017 Neuroreport 28-268.pdf.jpg22-Mar-20174-Phenylbutyric acid and metformin decrease sensitivity to pentylenetetrazol-induced seizures in a malin knockout model of Lafora disease.Sánchez-Elexpuru, Gentzane; Serratosa, José M.; Sanz, Pascual CSIC ORCID ; Sánchez, Marina P.artículo
openAccess2018 Epilepsy Res 145-169 Author copy.pdf.jpgSep-2018A novel EPM2A mutation yields a slow progression form of Lafora diseaseGarcía-Gimeno, María Adelaida CSIC ORCID; Rodilla-Ramirez, Pilar Natalia; Viana, Rosa CSIC ORCID ; Salas-Puig, Xavier; Brewer, M. Kathryn; Gentry, Matthew S.; Sanz, Pascual CSIC ORCID artículo
openAccessPlos One 2011.pdf.jpg30-Jun-2011A PTG Variant Contributes to a Milder Phenotype in Lafora DiseaseGuerrero, Rosa; Vernia, Santiago CSIC ORCID; Sanz, Raúl; Abreu-Rodríguez, Irene; Almaraz, Carmen; García-Hoyos, María; Michelucci, Roberto; Tassinari, Carlo Alberto; Riguzzi, Patrizia; Nobile, Carlo; Sanz, Pascual CSIC ORCID ; Serratosa, José M.; Gómez-Garre, Pilarartículo
openAccess2008 FEBS Letters 582-2650.pdf.jpg23-Jul-2008A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanismMoreno, Daniel; Knecht, Erwin; Viollet, Benoit; Sanz, Pascual CSIC ORCID artículo
openAccessprotein_kinase_Vernia.pdf.jpg27-Mar-2009AMP-activated protein kinase phosphorylates R5/PTG, the glycogen targeting subunit of the R5/PTG-PP1 holoenzyme and accelerates its downregulation by the laforin-malin complexVernia, Santiago CSIC ORCID; Solaz-Fuster, Maria Carmen CSIC; Gimeno-Alcañiz, José Vicente; Rubio, Teresa; García-Haro, Luisa CSIC; Foretz, Marc; Rodríguez de Córdoba, Santiago CSIC ORCID ; Sanz, Pascual CSIC ORCID artículo
openAccess2008 Curr Protein Pept Sci 9-478.pdf.jpgOct-2008AMP-activated protein kinase: structure and regulation.Sanz, Pascual CSIC ORCID artículo
openAccessAuthor copy MiMB 2018.pdf.jpg12-Apr-2018AMPK Protein Interaction Analyses by Yeast Two-HybridSanz, Pascual CSIC ORCID ; Viana, Rosa CSIC ORCID ; García-Gimeno, María Adelaida CSIC ORCIDartículo
openAccess2013 FEBS J 280-3723.pdf.jpg24-Jun-2013AMPKbeta subunits, more than just a scaffold in the formation of AMPK complexSanz, Pascual CSIC ORCID ; Rubio, Teresa; García-Gimeno, María Adelaida CSIC ORCIDartículo
openAccess2017 EMBO J 36-1946 Vers Aut.pdf.jpg3-Jul-2017AMPKα1-LDH pathway regulates muscle stem cell self-renewal by controlling metabolic homeostasis.Theret, Marine; Gsaier, Linda; Schaffer, Bethany; Juban, Gaëtan; Ben Larbi, Sabrina; Weiss-Gayet, Michèle; Bultot, Laurent; Collodet, Caterina; Foretz, Marc; Desplanches, Dominique; Sanz, Pascual CSIC ORCID ; Zang, Zizhao; Yang, Lin; Vial, Guillaume; Viollet, Benoit; Sakamoto, Kei; Brunet, Anne; Chazaud, Bénédicte; Mounier, Rémiartículo
openAccess13-Oct-2021An empirical pipeline for personalized diagnosis of Lafora disease mutationsBrewer, M. Kathryn; Machio-Castello, Maria; Viana, Rosa CSIC ORCID ; Wayne, Jeremiah L.; Kuchtová, Andrea; Simmons, Zoe R.; Sternbach, Sarah; Li, Sheng; García-Gimeno, María Adelaida CSIC ORCID; Serratosa, José M.; Sanz, Pascual CSIC ORCID ; Vander Kooi, Craig W.; Gentry, Matthew S.artículo
openAccess2018 Hum Mol Genet 27-1290 vers aut.pdf.jpg1-Apr-2018Astrocytes: new players in progressive myoclonus epilepsy of Lafora typeRubio-Villena, Carla CSIC; Viana, Rosa CSIC ORCID ; Bonet, Jose; García-Gimeno, María Adelaida CSIC ORCID; Casado, Marta CSIC ORCID ; Heredia, Miguel; Sanz, Pascual CSIC ORCID artículo
openAccess2021 Int J Mol Sci 22-5351.pdf.jpg19-May-2021Beneficial Effects of Metformin on the Central Nervous System, with a Focus on Epilepsy and Lafora DiseaseSanz, Pascual CSIC ORCID ; Serratosa, José Maria; Sánchez, Marina P.artículo de revisión
openAccess2008 J. Hum Genet 53-460.pdf.jpg6-Mar-2008Biochemical characterization of novel glucokinase mutations isolated from Spanish maturity onset diabetes of the young (MODY2) patientsEstalella, Itziar; García-Gimeno, María Adelaida CSIC ORCID; Marina, Alberto CSIC ORCID ; Castaño, Luis; Sanz, Pascual CSIC ORCID artículo
openAccess2020 Cannabis and Cannabinoid Research 05-150 vers autor.pdf.jpg5-Jun-2020Cannabidiol-Enriched Extract Reduced the Cognitive Impairment but Not the Epileptic Seizures in a Lafora Disease Animal ModelAso, Ester; Andrés-Benito, Pol; Grau-Escolano, Jordi; Caltana, Laura; Brusco, Alicia; Sanz, Pascual CSIC ORCID ; Ferrer, Isidroartículo
openAccess2111495_B1.pdf.jpg1-Nov-1998Cepa de levadura de panadería CECT10868 y cepa de panadería CECT10869. Su método de obtención por técnicas de ADN recombinante y su aplicación como levaduras de panaderíaSanz, Pascual CSIC ORCID ; Prieto Alamán, José Antonio CSIC ORCID; Pérez-González, José A.; Ramón, Daniel CSIC; Monfort Roig, Aureliapatente
openAccessES2623082B1.pdf.jpg10-Jul-2017Compuestos espiranicos derivados de oxindol-pirazolo[3,4-b]piridinona y sus usos terapéuticosCastro, Ana CSIC ORCID; Sanz, Pascual CSIC ORCID ; Quesada Sánchez, Sergio; García Gimeno, María Adelaida; Luque Garriga, Francisco Javier; Bidon-Chanal Badia, Axelpatente
openAccessES2623082A1.pdf.jpg10-Jul-2017Compuestos espiranicos derivados de oxindol-pirazolo[3,4-b]piridinona y sus usos terapéuticosCastro, Ana CSIC ORCID; Sanz, Pascual CSIC ORCID ; Quesada Sánchez, Sergio; García Gimeno, María Adelaida; Luque Garriga, Francisco Javier; Bidon-Chanal Badia, Axelsolicitud de patente
openAccesspicrender.pdf.jpg2-Apr-2007A conserved sequence immediatelly N-terminal to the bateman domains in AMP-activated protein kinase gamma subunits is required for the interaction with the beta subunitsViana, Rosa CSIC ORCID ; Towler, Mhairi; Pan, David A.; Carling, David; Viollet, Benoit; Hardie, D. Grahame; Sanz, Pascual CSIC ORCID artículo
closedAccessSep-2002Convergence of the TOR and the Snf1 protein kinase pathways in the regulation of the subcellular localization of Msn2, a transcriptional activator of STRE regulated genesMayordomo, Isabel; Estruch, Francisco; Sanz, Pascual CSIC ORCID artículo
openAccess2012 IUBMB life 64-801.pdf.jpg20-Jul-2012Deciphering the role of malin in the Lafora progressive myoclonus epilepsyRomá-Mateo, Carlos CSIC ORCID CVN; Sanz, Pascual CSIC ORCID ; Gentry, Matthew S.artículo