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openAccessG5K_JMB2007.pdf.jpg13-Apr-2007A Novel Two-domain Architecture Within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia coli Glutamate 5-kinaseMarco-Marín, Clara CSIC ORCID; Gil-Ortiz, Fernando CSIC ORCID; Pérez-Arellano, Isabel CSIC; Cervera, Javier; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
openAccess2016 Brain 139-e3 Author vers.pdf.jpgJan-2016ALDH18A1 gene mutations cause dominant spastic paraplegia SPG9: loss of function effect and plausibility of a dominant negative mechanismPanza, Emanuele; Escamilla-Honrubia, Juan Manuel; Marco-Marín, Clara CSIC ORCID; Gougeard, Nadine CSIC; De Michele, Giuseppe; Brescia Morra, Vincenzo; Liguori, Rocco; Salviati, Leonardo; Donati, Maria Alice; Cusano, Roberto; Pippucci, Tommaso; Ravazzolo, Roberto; Nemeth, Andrea H; Smithson, Sarah; Davies, Sally; Hurst, Jane A; Bordo, Domenico; Rubio, Vicente CSIC ORCID ; Seri, Marcoartículo
closedAccessaccesoRestringido.pdf.jpgOct-2019Arabidopsis ALIX Regulates Stomatal Aperture and Turnover of Abscisic Acid ReceptorsGarcía-León, Marta; Cuyas, Laura; El-Moneim, Diaa Abd; Rodriguez, Lesia; Belda-Palazón, Borja CSIC ORCID; Sánchez-Quant, Eva; Fernández, Yolanda; Roux, Brice; Zamarreño, Ángel M.; García-Mina, José María; Nussaume, Laurent; Rodriguez, Pedro L.; Paz-Ares, Javier; Leonhardt, Nathalie; Rubio, Vicente CSIC ORCID artículo
openAccessRUBIO,  Vicente.pdf.jpgSep-2019Arabidopsis CRL4 Complexes: Surveying Chromatin States and Gene ExpressionFonseca, Sandra; Rubio, Vicente CSIC ORCID artículo
openAccess2008 Curr Opin Struct Biol 18-673_vers_aut.pdf.jpgDec-2008Arginine and nitrogen storageLlácer, José Luis CSIC ORCID ; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2020Biochemical and Imaging Analysis of ALIX Function in Endosomal Trafficking of Arabidopsis Protein CargoesGarcía-León, Marta; Rubio, Vicente CSIC ORCID artículo
openAccess2022 Clin Genet 101-481.pdf.jpgMay-2022CIBERER: Spanish national network for research on rare diseases: A highly productive collaborative initiativeLuque, Juan; Mendes, Ingrid; Gómez, Beatriz; Morte, Beatriz CSIC ORCID; de Heredia, Miguel; Lopez Herreras, Enrique; Corrochano, Virginia; Bueren, Juan; Gallano, Pia; Artuch, Rafael; Fillat, Cristina; Pérez-Jurado, Luis A.; Montoliu, Lluís CSIC ORCID ; Carracedo, Angel; Millan, Jose M.; Webb, Susan M.; Palau, Francesc; CIBERER Network; Lapunzina, Pablo; Albiñana, Virginia CSIC; Arjona, Emilia CSIC ORCID ; Bernabéu, Carmelo CSIC ORCID ; Botella, Luisa M.; Pinto, Sheila CSIC; Rodríguez de Córdoba, Santiago ; Ruiz, Ángela; Antiñolo, Guillermo CSIC ORCID; Borrego, Salud CSIC ORCID; Bravo-Gil, Nereida; González-del Pozo, María; Méndez-Vidal, Cristina CSIC ORCID; Arbones, Maria L. CSIC ORCID ; Caparrós-Martín, José Antonio; Cediel, Rafael CSIC; Contreras, Julio CSIC; Estañ, María Cristina CSIC; Guerrero, Rosa; Jiménez-Estrada, Juan Andrés; Manguan-García, Cristina CSIC; Murillo-Cuesta, Silvia CSIC ORCID; Palencia-Campos, Adrián; Perona Abellón, Rosario CSIC ORCID; Rivera-Barahona, Ana CSIC; Rodríguez de la Rosa, Lourdes; Ruiz-Pérez, Victor L. CSIC ORCID; Sastre, Leandro CSIC ORCID; Valencia, María CSIC; Varela-Nieto, Isabel CSIC ORCID ; Cervera, Javier; Cima, Sergio de; Gougeard, Nadine CSIC; Heredia, Miguel CSIC; Llácer, José Luis CSIC ORCID ; Marco-Marín, Clara CSIC ORCID; Marina, Alberto CSIC ORCID ; Mollá, Belén CSIC ORCID; Moreno, Mireia; Pérez-Jiménez, Eva; Rubio, Vicente CSIC ORCID ; Sanz, Pascual CSIC ORCID ; Cortés-Rodríguez, Ana; Navas, Plácido CSIC ORCID; Sánchez Cuesta, Ana María; Santos-Ocaña, Carlos CSIC ORCID ; Fraga, Mario F.; Nieto, M. Ángela CSIC ORCID artículo de revisión
openAccess2013 Mol Genet Metab 110-181 Author vers.pdf.jpgSep-2013Citrin deficiency in a Romanian child living in Spain highlights the worldwide distribution of this defect and illustrates the value of nutritional therapyVitoria, Isidro; Dalmau, Jaime; Ribes, Carmen; Rausell, Dolores; García, Ana María; Lopez-Montiel, Javier; Rubio, Vicente CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg16-Jun-2020COP1 destabilizes DELLA proteins in ArabidopsisBlanco-Touriñán, Noel; Legris, Martina; Minguet, Eugenio G.; Costigliolo-Rojas, Cecilia; Nohales, María A.; Iniesto Sánchez, Elisa; García-León, Marta; Pacín, Manuel; Heucken, Nicole; Blomeier, Tim; Locascio, Antonella CSIC ORCID; Cerný, Martin; Esteve-Bruna, David; Díez-Díaz, Mónica; Brzobohatý, Břetislav; Frerigmann, Henning; Zurbriggen, Matías D.; Kay, Steve A.; Rubio, Vicente CSIC ORCID ; Blázquez, Miguel Ángel CSIC ORCID; Casal, Jorge J.; Alabadí, David CSIC ORCID artículo
openAccess5-Oct-2022CryoEM structures of the SARS-CoV-2 spike bound to antiviralsLópez-Redondo, María Luisa; Marco-Marín, Clara CSIC ORCID; Gougeard, Nadine CSIC; Forcada-Nadal, Alicia CSIC ORCID; Adhav, Anmol; Zamora-Caballero, Sara; Melero, Roberto CSIC ORCID; Hurtado, Ramón; Peréz-Pérez, María-Jesús CSIC ORCID ; Bravo Sicilia, Jerónimo; Rubio, Vicente CSIC ORCID ; Marina, Alberto CSIC ORCID ; Llacer Guerri, Jose Luisactas de congreso
closedAccessaccesoRestringido.pdf.jpg11-Sep-2014Crystal structures of human carbamoyl phosphate synthetase 1 (CPS1) shed light on domains functions, substrate tunnels and allosteric activation, and allow rationalization of inborn CPS1 deficiencyCima, Sergio de; Polo, Luis Mariano CSIC ORCID; Díez-Fernández, Carmen CSIC; Cervera, Javier; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpg17-Mar-2020CUL3BPM E3 ubiquitin ligases regulate MYC2, MYC3, and MYC4 stability and JA responsesChico, Jose Manuel; Lechner, Esther; Fernández-Barbero, G.; Canibano, Esther; García-Casado, Gloria; Franco-Zorrilla, José Manuel; Hammann, Philippe; Zamarreño, Ángel M.; García-Mina, José María; Rubio, Vicente CSIC ORCID ; Genschik, Pascal; Solano, Robertoartículo
closedAccessaccesoRestringido.pdf.jpg6-Sep-2016Deciphering carbamoyl phosphate synthetase (CPS1) deficiency and urea cycle regulation by determining the structures of human CPS1 in the absence and in the presence of N-acetyl-L-glutamate.Cima, Sergio de; Polo, Luis Mariano CSIC ORCID; Díez-Fernández, Carmen CSIC; Martínez, Ana I.; Cervera, Javier; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID póster de congreso
openAccesssebbm2015_Juanma.pdf.jpg7-Sep-2015Deciphering the mechanism by which 1-pyrrolin-5-carboxylate synthetase defects associate with dominant and recessive human pathologiesEscamilla Honrubia, Juan Manuel CSIC ORCID; Marco-Marín, Clara CSIC ORCID; Gougeard, Nadine CSIC; Rubio, Vicente CSIC ORCID póster de congreso
openAccess2022 Front Vet Sci  09-826991.pdf.jpg12-Oct-2022Detection of SARS-CoV-2 in a dog with hemorrhagic diarrheaPadilla-Blanco, Miguel; Vega, Santiago; Enjuanes Sánchez, Luis CSIC ORCID ; Morey, Alfonso; Lorenzo, Teresa; Marin, Clara; Ivorra, Carmen; Maiques, Elisa; Rubio, Vicente CSIC ORCID ; Rubio-Guerri, Consueloartículo
openAccess2022 Eur J Med Chem 232-114206.pdf.jpg15-Mar-2022Discovery of 3H-pyrrolo[2,3-c]quinolines with activity against Mycobacterium tuberculosis by allosteric inhibition of the glutamate-5-kinase enzymePanciera, Michele; Lence, Emilio; Rodríguez, Ángela; Gracia, Begoña; Aínsa, José A.; Marco-Marín, Clara CSIC ORCID; Rubio, Vicente CSIC ORCID ; Duarte Correia, Carlos Roque; González-Bello, Concepciónartículo
openAccess2017 Environ Microbiol Rep 9 Vers Autor.pdf.jpg12-Apr-2017Effects of T-loop modification on the PII-signaling protein: Structure of uridylylated Escherichia coli GlnB bound to ATPPalanca, Carles CSIC; Rubio, Vicente CSIC ORCID artículo
openAccessepigenetic_switch_repressive_permissive_chromatin_response_cold_stress.pdf.jpg5-Jun-2018Epigenetic switch from repressive to permissive chromatin in response to cold stressPark, Junghoon; Lim, Chae Jin; Shen, Mingzhe; Park, Hee Jin; Cha, Joon-Yung; Iniesto, Elisa; Rubio, Vicente CSIC ORCID ; Mengiste, Tesfaye; Zhu, Jian-Kang; Bressan, Ray A.; Lee, Sang Yeol; Lee, Byeong-ha; Jin, Jing Bo; Pardo, José M. CSIC ORCID ; Kim, Woe-Yeon; Yun, Dae-Jinartículo
openAccess2016 Front Micb-07-01677.pdf.jpg28-Oct-2016Expandin Cyanobacterial Nitrogen Regulatory Network: The GntR-Like Regulator PlmA Interacts with the PII-PipX ComplexLabella, José I.; Obrebska, Anna; Espinosa, Javier; Salinas, Paloma; Forcada-Nadal, Alicia CSIC ORCID; Tremino-Agulló, Lorena CSIC ORCID; Rubio, Vicente CSIC ORCID ; Contreras, Asunciónartículo
openAccess2021 FEBS J 288-1142.pdf.jpgFeb-2021Functional and structural characterization of PII-like protein CutA does not support involvement in heavy metal tolerance and hints at a small-molecule carrying/signaling roleSelim, Khaled A.; Tremino-Agulló, Lorena CSIC ORCID; Marco-Marín, Clara CSIC ORCID; Alva, Vikram; Espinosa, Javier; Contreras, Asunción; Hartmann, Marcus D.; Forchhammer, Karl; Rubio, Vicente CSIC ORCID artículo