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openAccessG5K_JMB2007.pdf.jpg13-Apr-2007A Novel Two-domain Architecture Within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia coli Glutamate 5-kinaseMarco-Marín, Clara CSIC ORCID; Gil-Ortiz, Fernando CSIC ORCID; Pérez-Arellano, Isabel CSIC; Cervera, Javier; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
openAccess2023 Front Publ Health 11-1098965.pdf.jpg26-Jan-2023A SARS-CoV-2 full genome sequence of the B.1.1 lineage sheds light on viral evolution in Sicily in late 2020Padilla-Blanco, Miguel; Gucciardi, Francesca; Rubio, Vicente CSIC ORCID ; Lastra, Antonio; Lorenzo, Teresa; Ballester, Beatriz; González-Pastor, Andrea; Veses, Verónica; Macaluso, Giusi; Sheth, Chirag C.; Pascual-Ortiz, Marina; Maiques, Elisa CSIC ORCID; Rubio-Guerri, Consuelo; Purpari, Giuseppa; Guercio, Annalisaartículo
openAccess2016 Brain 139-e3 Author vers.pdf.jpgJan-2016ALDH18A1 gene mutations cause dominant spastic paraplegia SPG9: loss of function effect and plausibility of a dominant negative mechanismPanza, Emanuele; Escamilla-Honrubia, Juan Manuel; Marco-Marín, Clara CSIC ORCID; Gougeard, Nadine CSIC ORCID; De Michele, Giuseppe; Brescia Morra, Vincenzo; Liguori, Rocco; Salviati, Leonardo; Donati, Maria Alice; Cusano, Roberto; Pippucci, Tommaso; Ravazzolo, Roberto; Nemeth, Andrea H; Smithson, Sarah; Davies, Sally; Hurst, Jane A; Bordo, Domenico; Rubio, Vicente CSIC ORCID ; Seri, Marcoartículo
closedAccessaccesoRestringido.pdf.jpgOct-2019Arabidopsis ALIX Regulates Stomatal Aperture and Turnover of Abscisic Acid ReceptorsGarcía-León, Marta; Cuyas, Laura; El-Moneim, Diaa Abd; Rodriguez, Lesia; Belda-Palazón, Borja CSIC ORCID; Sánchez-Quant, Eva; Fernández, Yolanda; Roux, Brice; Zamarreño, Ángel M.; García-Mina, José María; Nussaume, Laurent; Rodríguez, Pedro L. CSIC ORCID; Paz-Ares, Javier CSIC ORCID; Leonhardt, Nathalie; Rubio, Vicente CSIC ORCID artículo
openAccessRUBIO,  Vicente.pdf.jpgSep-2019Arabidopsis CRL4 Complexes: Surveying Chromatin States and Gene ExpressionFonseca, Sandra; Rubio, Vicente CSIC ORCID artículo
openAccess2008 Curr Opin Struct Biol 18-673_vers_aut.pdf.jpgDec-2008Arginine and nitrogen storageLlácer, José Luis CSIC ORCID ; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2023Un ataque combinado químico, virológico, biofísico y estructural hace posible la obtención de nuevos inhibidores de entrada celular de SARS-CoV-2 y la caracterización de su mecanismo de inhibiciónGargantilla, Marta CSIC ORCID; Francés-Gómez, Clara CSIC ORCID; Adhav, Anmol CSIC ORCID; Forcada-Nadal, Alicia CSIC ORCID; Martínez-Gualda, Belén CSIC; Martí-Marí, Olaia CSIC ORCID; López-Redondo, Marisa CSIC; Melero, Roberto CSIC ORCID; Marco-Marín, Clara CSIC ORCID; IBV-Covid 19-Pipeline; Bravo, Jerónimo CSIC ORCID ; Llácer, José Luis CSIC ORCID ; Marina, Alberto CSIC ORCID ; Rubio, Vicente CSIC ORCID ; Geller, Ron CSIC ORCID comunicación de congreso
closedAccessaccesoRestringido.pdf.jpg2020Biochemical and Imaging Analysis of ALIX Function in Endosomal Trafficking of Arabidopsis Protein CargoesGarcía-León, Marta; Rubio, Vicente CSIC ORCID artículo
openAccess2023 J Med Chem 66-10432.pdf.jpg10-Aug-2023C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) ProteinGargantilla, Marta CSIC ORCID; Francés-Gómez, Clara CSIC ORCID; Adhav, Anmol CSIC ORCID; Forcada-Nadal, Alicia CSIC ORCID; Martínez-Gualda, Belén CSIC; Martí-Marí, Olaia CSIC ORCID; López-Redondo, Marisa CSIC; Melero, Roberto CSIC ORCID; Marco-Marín, Clara CSIC ORCID; Gougeard, Nadine CSIC ORCID; Espinosa, Carolina; Rubio-Del-Campo, Antonio; Ruiz-Partida, Rafael; Hernández-Sierra, María del Pilar; Villamayor-Belinchón, Laura; Bravo, Jerónimo CSIC ORCID ; Llácer, José Luis CSIC ORCID ; Marina, Alberto CSIC ORCID ; Rubio, Vicente CSIC ORCID ; San-Félix, Ana CSIC ORCID ; Geller, Ron CSIC ORCID ; Peréz-Pérez, María-Jesús CSIC ORCID artículo
openAccess2022 Clin Genet 101-481.pdf.jpgMay-2022CIBERER: Spanish national network for research on rare diseases: A highly productive collaborative initiativeLuque, Juan M. CSIC; Mendes, Ingrid; Gómez, Beatriz; Morte, Beatriz CSIC ORCID; Heredia, Miguel CSIC; Lopez Herreras, Enrique; Corrochano, Virginia; Bueren, Juan; Gallano, Pia; Artuch, Rafael; Fillat, Cristina CSIC; Pérez-Jurado, Luis Alberto; Montoliu, Lluís CSIC ORCID ; Carracedo, Ángel; Millán, José María; Webb, Susan M.; Palau, Francesc; CIBERER Network; Lapunzina, Pablo; Albiñana, Virginia CSIC; Arjona, Emilia CSIC ORCID ; Bernabéu, Carmelo CSIC ORCID ; Botella, Luisa María CSIC ORCID ; Pinto, Sheila CSIC; Rodríguez de Córdoba, Santiago ; Ruiz, Ángela; Antiñolo, Guillermo CSIC ORCID; Borrego, Salud CSIC ORCID; Bravo-Gil, Nereida CSIC; González-del Pozo, María; Méndez-Vidal, Cristina CSIC ORCID; Arbones, Maria L. CSIC ORCID ; Caparrós-Martín, José A. CSIC; Cediel, Rafael CSIC; Contreras, Julio CSIC; Estañ, María Cristina CSIC; Guerrero-López, Rosa CSIC; Jiménez-Estrada, Juan Andrés CSIC; Manguan-García, Cristina CSIC ORCID; Murillo-Cuesta, Silvia CSIC ORCID; Palencia-Campos, Adrián CSIC; Perona Abellón, Rosario CSIC ORCID; Rivera-Barahona, Ana CSIC; Rodriguez-de la Rosa, Lourdes CSIC ORCID; Ruiz-Pérez, Victor L. CSIC ORCID; Sastre, Leandro CSIC ORCID; Valencia, María CSIC; Varela-Nieto, Isabel CSIC ORCID ; Cervera, Javier; Cima, Sergio de CSIC ORCID; Gougeard, Nadine CSIC ORCID; Heredia, Miguel CSIC; Llácer, José Luis CSIC ORCID ; Marco-Marín, Clara CSIC ORCID; Marina, Alberto CSIC ORCID ; Mollá, Belén CSIC ORCID; Moreno-Estellés, Mireia CSIC ORCID; Pérez-Jiménez, Eva CSIC ORCID; Rubio, Vicente CSIC ORCID ; Sanz, Pascual CSIC ORCID ; Cortés-Rodríguez, Ana; Navas, Plácido CSIC ORCID; Sánchez Cuesta, Ana María; Santos-Ocaña, Carlos CSIC ORCID ; Fraga, Mario F. CSIC ORCID; Nieto, M. Ángela CSIC ORCID artículo de revisión
openAccess2013 Mol Genet Metab 110-181 Author vers.pdf.jpgSep-2013Citrin deficiency in a Romanian child living in Spain highlights the worldwide distribution of this defect and illustrates the value of nutritional therapyVitoria, Isidro; Dalmau, Jaime; Ribes, Carmen; Rausell, Dolores; García, Ana María; Lopez-Montiel, Javier; Rubio, Vicente CSIC ORCID artículo
openAccessRGA-LIKE_2_Lee_Art_2022.pdf.jpgJul-2022CONSTITUTIVE PHOTOMORPHOGENIC 1 promotes seed germination by destabilizing RGA-LIKE 2 in ArabidopsisLee, Byoung-Doo; Yim, Yehyun; Cañibano, Esther; Kim, Suk-Hwan; García-León, Marta; Rubio, Vicente CSIC ORCID ; Fonseca, Sandra; Paek, Nam-Chonartículo
closedAccessaccesoRestringido.pdf.jpg16-Jun-2020COP1 destabilizes DELLA proteins in ArabidopsisBlanco-Touriñán, Noel; Legris, Martina; Minguet, Eugenio G.; Costigliolo-Rojas, Cecilia; Nohales, María-Ángeles CSIC ORCID; Iniesto Sánchez, Elisa CSIC ORCID; García-León, Marta; Pacín, Manuel; Heucken, Nicole; Blomeier, Tim; Locascio, Antonella CSIC ORCID; Cerný, Martin; Esteve-Bruna, David; Díez-Díaz, Mónica; Brzobohatý, Břetislav; Frerigmann, Henning; Zurbriggen, Matías D.; Kay, Steve A.; Rubio, Vicente CSIC ORCID ; Blázquez, Miguel Ángel CSIC ORCID; Casal, Jorge J.; Alabadí, David CSIC ORCID artículo
openAccess5-Oct-2022CryoEM structures of the SARS-CoV-2 spike bound to antiviralsLópez-Redondo, Marisa CSIC; Marco-Marín, Clara CSIC ORCID; Gougeard, Nadine CSIC ORCID; Forcada-Nadal, Alicia CSIC ORCID; Adhav, Anmol CSIC ORCID; Zamora-Caballero, Sara; Melero, Roberto CSIC ORCID; Hurtado, Ramón; Peréz-Pérez, María-Jesús CSIC ORCID ; Bravo Sicilia, Jerónimo; Rubio, Vicente CSIC ORCID ; Marina, Alberto CSIC ORCID ; Llacer Guerri, Jose Luiscomunicación de congreso
closedAccessaccesoRestringido.pdf.jpg11-Sep-2014Crystal structures of human carbamoyl phosphate synthetase 1 (CPS1) shed light on domains functions, substrate tunnels and allosteric activation, and allow rationalization of inborn CPS1 deficiencyCima, Sergio de CSIC ORCID; Polo, Luis Mariano CSIC ORCID; Díez-Fernández, Carmen CSIC; Cervera, Javier; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpg17-Mar-2020CUL3BPM E3 ubiquitin ligases regulate MYC2, MYC3, and MYC4 stability and JA responsesChico, Jose Manuel; Lechner, Esther; Fernández-Barbero, G.; Cañibano, Esther; García-Casado, Gloria; Franco-Zorrilla, José Manuel ; Hammann, Philippe; Zamarreño, Ángel M.; García-Mina, José María; Rubio, Vicente CSIC ORCID ; Genschik, Pascal; Solano, Roberto CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg6-Sep-2016Deciphering carbamoyl phosphate synthetase (CPS1) deficiency and urea cycle regulation by determining the structures of human CPS1 in the absence and in the presence of N-acetyl-L-glutamate.Cima, Sergio de CSIC ORCID; Polo, Luis Mariano CSIC ORCID; Díez-Fernández, Carmen CSIC; Martínez, Ana I.; Cervera, Javier; Fita, Ignacio CSIC ORCID ; Rubio, Vicente CSIC ORCID póster de congreso
openAccesssebbm2015_Juanma.pdf.jpg7-Sep-2015Deciphering the mechanism by which 1-pyrrolin-5-carboxylate synthetase defects associate with dominant and recessive human pathologiesEscamilla Honrubia, Juan Manuel CSIC ORCID; Marco-Marín, Clara CSIC ORCID; Gougeard, Nadine CSIC ORCID; Rubio, Vicente CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpg7-Jun-2021DET1-mediated COP1 regulation avoids HY5 activity over second-site gene targets to tune plant photomorphogenesisCañibano, Esther; Bourbousse, Clara; García-León, Marta; Garnelo Gómez, Borja; Wolff, Léa; García-Baudino, Camila; Lozano-Durán, Rosa; Barneche, Fredy; Rubio, Vicente CSIC ORCID ; Fonseca, Sandraartículo
openAccessDET1-mediated_Nassrallah_Art_2018.pdf.jpg2018DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasisNassrallah, Amr; Rougée, Martin; Bourbousse, Clara; Drevensek, Stephanie; Fonseca, Sandra; Iniesto Sánchez, Elisa CSIC ORCID; Ait-Mohamed, Ouardia; Deton-Cabanillas, Anne-Flore; Zabulon, Gerald; Ahmed, Ikhlak; Troebel, David S; Masson, Vanessa; Lombard, Berangere; Eeckhout, Dominique; Gevaert, Kris; Loew, Damarys; Genovesio, Auguste G; Breyton, Cecile; Jaeger, Geert De; Bowler, Chris; Rubio, Vicente CSIC ORCID artículo