English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/80917
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


Fatty acids intake and immune parameters in the elderly

Other TitlesIngesta de ácidos grasos y parámetros inmunes en ancianos
AuthorsGonzález, Sonia; López, Patricia ; Margolles Barros, Abelardo ; Suárez, Ana; Patterson, Ángeles M.; Cuervo, Adriana; González de los Reyes-Gavilán, Clara ; Gueimonde Fernández, Miguel
Issue Date2013
PublisherAula Médica Ediciones
CitationNutricion Hospitalaria 28(2): 474-478 (2013)
AbstractIntroduction: The rapid increase on life-expectancy represents a major challenge and economic burden for modern societies. Several studies have focused on the effects of polyunsaturated fatty acids (PUFA) upon the immune system; however less attention has been paid to the effects of monounsaturated fatty acids (MUFA). In this work we investigated the relationship of habitual consumption of different types of fatty acids with different immune parameters in the elderly. Subjects and methods: 40 institutionalized elderly (76-95 y) and 35 home-living middle-age subjects (57-65 y) were recruited. Dietary intakes of macronutrients, fiber and fatty acids, as well as immune parameters such as serum cytokines levels (IL-10, TNF-α, IL-8, IL-17, TGF-β and IL-12), phagocytic activity and cytotoxic NK activity, were determined. Results: Elderly subjects had a lower intake of total lipids. MUFA intake was significantly lower in the elderly group than in middle-age adults whilst the contrary was true for PUFA. MUFA intake in the elderly was found to be positively associated with IL-12 (β = 0.879) and TNF-α (β = 0.789) serum concentrations, whilst PUFA intake was inversely related to levels of IL-12 (β = -0.534). These associations were not observed in the middle-age group. Conclusion: MUFA intake may contribute to the pro-inflammatory status present in the elderly. It may be advisable to develop future nutrient recommendations specific for elderly taking into account immune parameters.
Publisher version (URL)http://dx.doi.org/10.3305/nh.2013.28.2.6183
Identifiersdoi: 10.3305/nh.2013.28.2.6183
issn: 0212-1611
e-issn: 1699-5198
Appears in Collections:(IPLA) Artículos
Files in This Item:
File Description SizeFormat 
fatty_acids_Gonzalez.pdf99,43 kBAdobe PDFThumbnail
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.