Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/80242
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Programmed cell death in the development of the vertebrate inner ear |
Autor: | León, Yolanda CSIC ORCID; Sánchez-Galiano, Susana CSIC; Gorospe, Itziar | Fecha de publicación: | 2004 | Editor: | Springer Nature | Citación: | Apoptosis 9(3): 255-264 (2004) | Resumen: | Programmed cell death is known to be an essential process for accurate ontogeny during the normal development of the inner ear. The inner ear is a complex sensory organ responsible for equilibrium and sound detection in vertebrates. In all vertebrates, the inner ear develops from a single ectodermic patch on the surface of the embryo's head, which undergoes a series of morphological changes to give rise to the complex structure of the adult inner ear. Enlargement and morphogenesis of the inner ear primordium is likely to depend on cellular division, growth, migration, differentiation and apoptosis. Here we describe the regions of programmed cell death that contribute to the final morphological aspect of the adult inner ear. The few studies that focus on the molecules that control this process during inner ear development indicate that the molecules and intracellular signaling pathways activated during the apoptotic response in the inner ear are similar to the previously described for the nervous system. In this review, we will describe some of the growth factors and key pathways that regulate pro- and anti-apoptotic signals and how they cross talk to determine the apoptotic or survival fate of cells in the development of the inner ear. | URI: | http://hdl.handle.net/10261/80242 | DOI: | 10.1023/B:APPT.0000025802.07676.a5 | Identificadores: | doi: 10.1023/B:APPT.0000025802.07676.a5 issn: 1360-8185 e-issn: 1573-675X |
Aparece en las colecciones: | (IIBM) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
35
checked on 13-abr-2024
WEB OF SCIENCETM
Citations
30
checked on 24-feb-2024
Page view(s)
321
checked on 19-abr-2024
Download(s)
98
checked on 19-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.