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dc.contributor.authorVillar, Ana-Victoria-
dc.contributor.authorAlonso, Alicia-
dc.contributor.authorPañeda, Covadonga-
dc.contributor.authorVarela-Nieto, Isabel-
dc.contributor.authorBrodbeck, Urs-
dc.contributor.authorGoñi, Félix M.-
dc.date.accessioned2013-07-12T12:29:21Z-
dc.date.available2013-07-12T12:29:21Z-
dc.date.issued1999-
dc.identifierdoi: 10.1016/S0014-5793(99)01010-8-
dc.identifierissn: 0014-5793-
dc.identifiere-issn: 1873-3468-
dc.identifier.citationFEBS Letters 457(1): 71-74 (1999)-
dc.identifier.urihttp://hdl.handle.net/10261/79584-
dc.description.abstractLarge unilamellar vesicles consisting of phospholipids with or without cholesterol have been prepared containing GPI and/or gangliosides asymmetrically located in the outer leaflet of the bilayer. Such asymmetric distribution of GPI and gangliosides is found in 'rafts' and caveolae. Using these vesicles, GPI can be readily hydrolysed by phospholipases. Both cholesterol and ganglioside are seen to inhibit, in an additive way, the hydrolytic activity of GPI-specific phospholipase D. Copyright (C) 1999 Federation of European Biochemical Societies.-
dc.description.sponsorshipThis work was supported in part by funds from CICYT (Grant PB96/0171), the Basque Government (Grants EX98/28 and PI98/32), and the University of the Basque Country (G03/98). A.-V.V. is the recipient of a scholarship from the University of the Basque Country.-
dc.language.isoeng-
dc.publisherElsevier-
dc.rightsclosedAccess-
dc.titleTowards the in vitro reconstitution of caveolae. Asymmetric incorporation of glycosylphosphatidylinositol (GPI) and gangliosides into liposomal membranes-
dc.typeartículo-
dc.identifier.doi10.1016/S0014-5793(99)01010-8-
dc.date.updated2013-07-12T12:29:21Z-
dc.description.versionPeer Reviewed-
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