English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/78961
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Título

Allelic status of chromosome 1 in neoplasms of the nervous system

AutorBello, M. Josefa; Leone, Paola E.; Nebreda, Paloma; Pestaña, Ángel ; Rey, Juan A.
Fecha de publicación1995
EditorElsevier
CitaciónCancer Genetics and Cytogenetics 83(2): 160-164 (1995)
ResumenBy using five highly polymorphic markers, the allelic status of chromosome 1 was established in a series of 236 tumors of the nervous system, including all major histologic subtypes: gliomas, meningiomas, neurinomas, neuroblastomas, medulloblastomas, etc. Loss of alleles at 1p was observed at significant frequencies in neuroblastomas (26% of cases), meningiomas (32%) and malignant gliomas (37%) (primarily oligodendrogliomas [94%]). This anomaly was also detected in two of 23 neurinomas, two of three neurofibrosarcomas, one primary lymphoma, and two metastatic tumors of the brain. The analysis of tumors displaying partial 1p deletions suggests the existence of two distinct regions, 1p36 and 1p35-p32, in which loci nonrandomly involved in the development of neurogenic neoplasms might be located.
URIhttp://hdl.handle.net/10261/78961
DOI10.1016/0165-4608(95)00064-V
Identificadoresdoi: 10.1016/0165-4608(95)00064-V
issn: 0165-4608
e-issn: 1873-4456
Aparece en las colecciones: (IIBM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
accesoRestringido.pdf15,38 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.