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dc.contributor.authorGarcillán-Barcia, M. Pilar-
dc.contributor.authorCruz, Fernando de la-
dc.contributor.authorCoque, Teresa M.-
dc.identifierdoi: 10.1128/AAC.01448-10-
dc.identifierissn: 0066-4804-
dc.identifiere-issn: 1098-6596-
dc.identifier.citationAntimicrobial Agents and Chemotherapy 55(5): 2451-2457 (2011)-
dc.descriptionet al.-
dc.description.abstractThe association of an IS440-sul3 platform with Tn21 class 1 integrons carried by IncI1 plasmids encoding extended-spectrum β-lactamases (ESBLs; mainly SHV-12 and CTX-M-14) among worldwide Escherichia coli clones of phylogroups A (ST10, ST23, and ST46), B1 (ST155, ST351, and ST359), and D/B2 (ST131) is reported. An in silico comparative analysis of sul3 elements available in the GenBank database shows the evolution of sul3 platforms by hosting different transposable elements facilitating the potential genesis of IS26 composite transposons and further insertion element-mediated promoted arrangements. Copyright © 2011, American Society for Microbiology. All Rights Reserved.-
dc.description.sponsorshipT.C. and M.P.G.-B. are supported by fellow research contracts from the Spanish Ministry of Science and Innovation (grant FI09/00901) and from Consejo Superior de Investigaciones Científicas (JAE-Doc), respectively. This study and the work done by the IRYCIS group were funded by research grants from the European Commission (LSHMCT-2008-223031 and KBBE-2008-2B-227258) and by the CIBERESP Network for Biomedical Research in Epidemiology and Public Health (Instituto Carlos III, Spanish Ministry of Science and Innovation; reference no. CB06/02/0053). Work completed in the FdlC laboratory was supported by grants BFU2008-00995/BMC (Spanish Ministry of Education), REIPI RD06/0008/1012 (RETICS research network, Instituto de Salud Carlos III, Spanish Ministry of Science and Innovation), and LSHM-CT-2005_019023 (European VI Framework Program). We also are grateful to the Spanish Network for the Study of Plasmids and Extrachromosomal Elements (REDEEX) for encouraging and funding cooperation among Spanish microbiologists working on the biology of mobile genetic elements (grant BFU 2008-0079-E/ BMC; Spanish Ministry of Science and Innovation).-
dc.publisherAmerican Society for Microbiology-
dc.titleAssociation of composite IS26-sul3 elements with highly transmissible IncI1 plasmids in extended-spectrum-β-lactamase-producing Escherichia coli clones from humans-
dc.description.versionPeer Reviewed-
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