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Título: | Activation of protein kinase C from B lymphocytes by lipid A |
Autor: | Boscá, Lisardo CSIC ORCID CVN ; Díaz-Guerra, María José | Fecha de publicación: | 1988 | Editor: | Elsevier | Citación: | Biochemical and Biophysical Research Communications 152(1): 149-154 (1988) | Resumen: | The effect of lipid A, a residue of the lipopolysaccharide molecule, on protein kinase C from B lymphocytes has been studied. Lipid A activates and promotes the translocation of protein kinase C from the soluble to the particulate membrane fraction in a cell-free system reconstituted with purified enzyme and membranes isolated from B lymphocytes. These results demonstrate that the activating effect of lipopolysaccharide on protein kinase C from B cells is due to the lipid moieties of this molecule. | URI: | http://hdl.handle.net/10261/78664 | DOI: | 10.1016/S0006-291X(88)80692-2 | Identificadores: | doi: 10.1016/S0006-291X(88)80692-2 issn: 0006-291X e-issn: 1090-2104 |
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