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Título: | How Institut Georges Lopez preservation solution protects nonsteatotic and steatotic livers against ischemia-reperfusion injury |
Autor: | Zaouali, Mohamed A. CSIC ORCID; Abdennebi, Hassen B.; Padrissa-Altés, Susagna CSIC; Alfany-Fernández, Isabel CSIC; Rimola, Antoni; Roselló-Catafau, Joan CSIC ORCID | Fecha de publicación: | 2011 | Editor: | Elsevier | Citación: | Transplantation Proceedings 43(1): 77-79 (2011) | Resumen: | The Institut Georges Lopez preservation solution (IGL-1) is a serum-free organ preservative that has been shown to protect steatotic livers against hepatic ischemia-reperfusion injury. Although several hypotheses have been proposed to explain the graft protection mechanisms induced by IGL-1 solution, they have not been fully investigated. This review assessed possible IGL-1 mechanisms responsible for the increased liver tolerance of ischemia-reperfusion injury with special emphasis on vasodilatator mediators such as nitric oxide, on oxidative stress prevention, on protection against mitochondrial damage, and finally on induction of cytoprotective factors. | Descripción: | El pdf es la versión post-print. | Versión del editor: | http://dx.doi.org/10.1016/j.transproceed.2010.12.026 | URI: | http://hdl.handle.net/10261/73548 | DOI: | 10.1016/j.transproceed.2010.12.026 | Identificadores: | doi: 10.1016/j.transproceed.2010.12.026 issn: 0041-1345 e-issn: 1873-2623 |
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How Institut Georges Lopez Preservation Solution Protects.pdf | 57,6 kB | Adobe PDF | Visualizar/Abrir |
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