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Open Access item Ubiquity and diversity of multidrug resistance genes in Lactococcus lactis strains isolated between 1936 and 1995

Authors:Flórez García, Ana Belén
González de los Reyes-Gavilán, Clara
Wind, Anette
Mayo Pérez, Baltasar
Margolles Barros, Abelardo
Keywords:Lactococcus lactis, Multidrug resistance, MDR-transporters
Issue Date:21-Aug-2006
Publisher:Federation of European Microbiological Societies
Citation:FEMS Microbiology Letters 263(1): 21-25 (2006)
Abstract:The presence and the nucleotide sequence of four multidrug resistance genes, lmrA, lmrP, lmrC, and lmrD, were investigated in 13 strains of Lactococcus lactis ssp. lactis, four strains of Lactococcus lactis ssp. cremoris, two strains of Lactococcus plantarum, and two strains of Lactococcus raffinolactis. Multidrug resistance genes were present in all L. lactis isolates tested. However, none of them could be detected in the strains belonging to the species L. raffinolactis and L. plantarum, suggesting a different set of multidrug resistance genes in these species. The analysis of the four deduced amino acid sequences established two different variants depending on the subspecies of L. lactis. Either lmrA, or lmrP, or both were found naturally disrupted in five strains, while full-length lmrD was present in all strains
URI:http://hdl.handle.net/10261/6804
ISSN:0378-1097
E-ISSNmetadata.dc.identifier.doi = DOI:1574-6968
???metadata.dc.identifier.doi???:10.1111/j.1574-6968.2006.00371.x
Appears in Collections:(IPLA) Artículos

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